Transgenic simulation of human heart failure-like L-type Ca2+-channels: implications for fibrosis and heart rate in mice. (Q37422609)

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2 February 2020

title

Transgenic simulation of human heart failure-like L-type Ca2+-channels: implications for fibrosis and heart rate in mice (English)

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2 February 2020

0 references

4

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2 February 2020

Jan Matthes

10

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2 February 2020

author name string

Nadine Beetz

1

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2 February 2020

Lutz Hein

2

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2 February 2020

Janos Meszaros

3

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Frederico Barreto

5

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2 February 2020

Marcel Meissner

6

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2 February 2020

Uta C Hoppe

7

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Arnold Schwartz

8

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Stefan Herzig

9

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publication date

20 July 2009

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2 February 2020

published in

Cardiovascular Research

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volume

84

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issue

3

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page(s)

396-406

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Ca2+- and mitochondrial-dependent cardiomyocyte necrosis as a primary mediator of heart failure

2 February 2020

cites work

1 reference

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Increased expression of the auxiliary beta(2)-subunit of ventricular L-type Ca(2)+ channels leads to single-channel activity characteristic of heart failure

23 August 2017

1 reference

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Role of beta-adrenergic receptor signaling and desensitization in heart failure: new concepts and prospects for treatment

23 August 2017

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The L-type calcium channel in the heart: the beat goes on

23 August 2017

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Heart failure -- a challenge to our current concepts of excitation-contraction coupling

23 August 2017

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Voltage-gated Ca2+ currents in the human pathophysiologic heart: a review

23 August 2017

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Novel functional properties of Ca(2+) channel beta subunits revealed by their expression in adult rat heart cells

23 August 2017

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Functional regulation of L-type calcium channels via protein kinase A-mediated phosphorylation of the beta(2) subunit

23 August 2017

1 reference

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Direct inhibition of cardiac hyperpolarization-activated cyclic nucleotide-gated pacemaker channels by clonidine

23 August 2017

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Cardiac L-type calcium channel beta-subunits expressed in human heart have differential effects on single channel characteristics

14 September 2017

1 reference

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Adenovirus-mediated inducible gene expression in vivo by a hybrid ecdysone receptor

14 September 2017

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L-type calcium channel abundance and function with cardiac hypertrophy and failure: a review

28 September 2017

1 reference

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Ca2+ currents in compensated hypertrophy and heart failure.

28 September 2017

1 reference

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Reduced effects of BAY K 8644 on L-type Ca2+ current in failing human cardiac myocytes are related to abnormal adrenergic regulation

28 September 2017

1 reference

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L-type Ca2+ channel density and regulation are altered in failing human ventricular myocytes and recover after support with mechanical assist devices

26 June 2018

1 reference

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Role of CaVbeta subunits, and lack of functional reserve, in protein kinase A modulation of cardiac CaV1.2 channels

26 June 2018

1 reference

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Heterozygous alpha 2C-adrenoceptor-deficient mice develop heart failure after transverse aortic constriction.

2 September 2018

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Gene therapy to inhibit the calcium channel beta subunit: physiological consequences and pathophysiological effects in models of cardiac hypertrophy

2 September 2018

1 reference

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Ca2+ influx-induced sarcoplasmic reticulum Ca2+ overload causes mitochondrial-dependent apoptosis in ventricular myocytes

2 September 2018

1 reference

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Creation of a genetic calcium channel blocker by targeted gem gene transfer in the heart

2 September 2018

1 reference

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Single-channel gating and regulation of human L-type calcium channels in cardiomyocytes of transgenic mice

2 September 2018

1 reference

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Feedback inhibition of catecholamine release by two different alpha2-adrenoceptor subtypes prevents progression of heart failure

2 September 2018

1 reference

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L-type calcium current in catecholamine-induced cardiac hypertrophy in the rat

2 September 2018

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12 December 2020

Increased availability and open probability of single L-type calcium channels from failing compared with nonfailing human ventricle

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12 December 2020

Cardiac-specific overexpression of the alpha(1) subunit of the L-type voltage-dependent Ca(2+) channel in transgenic mice. Loss of isoproterenol-induced contraction

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12 December 2020

A Ca(2+)-dependent transgenic model of cardiac hypertrophy: A role for protein kinase Calpha

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12 December 2020

Identifiers

DOI

10.1093/CVR/CVP251

1 reference

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2 February 2020

1 reference

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2 February 2020

PubMed publication ID

19620129

1 reference