Insight into the structure, function, and biosynthesis of factor VIII through recombinant DNA technology (Q37424095)

20 August 2017

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title

Insight into the structure, function, and biosynthesis of factor VIII through recombinant DNA technology (English)

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20 August 2017

R J Kaufman

1

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20 August 2017

publication date

1 September 1991

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20 August 2017

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20 August 2017

volume

63

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20 August 2017

issue

3

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20 August 2017

page(s)

155-165

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Interaction of factor VIII-von Willebrand Factor with phospholipid vesicles

20 August 2017

cites work

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https://api.crossref.org/works/10.1007%2FBF01703248

Reduction of endogenous GRP78 levels improves secretion of a heterologous protein in CHO cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF01703248

The size of human factor VIII heterodimers and the effects produced by thrombin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF01703248

Coamplification and coexpression of human tissue-type plasminogen activator and murine dihydrofolate reductase sequences in Chinese hamster ovary cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF01703248

Effect of von Willebrand factor coexpression on the synthesis and secretion of factor VIII in Chinese hamster ovary cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF01703248

The interaction between human blood-coagulation factor VIII and von Willebrand factor. Characterization of a high-affinity binding site on factor VIII.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF01703248

Intracellular maturation and transport of the SV5 type II glycoprotein hemagglutinin-neuraminidase: specific and transient association with GRP78-BiP in the endoplasmic reticulum and extensive internalization from the cell surface.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF01703248

Hemophilia in the Talmud and Rabbinic Writings

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF01703248

Complex regulation of heat shock- and glucose-responsive genes in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF01703248

Membrane and lipid involvement in blood coagulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF01703248

Inactivation of factor VIII by activated protein C and protein S

21 January 2018

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12 December 2020

Interaction of heavy chain binding protein (BiP/GRP78) with adenine nucleotides

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12 December 2020

Factor IX is activated in vivo by the tissue factor mechanism

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12 December 2020

Use of recombinant antihemophilic factor in the treatment of two patients with classic hemophilia

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12 December 2020

Thrombin activation of factor VIII: the effect of inhibitors

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12 December 2020

Coordinate binding of factor Va and factor Xa to the unstimulated platelet

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12 December 2020

Purification and characterization of factor VIII 1,689-Cys: a nonfunctional cofactor occurring in a patient with severe hemophilia A.

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12 December 2020

Ultrastructural localization of factor VIII procoagulant antigen in human liver hepatocytes

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12 December 2020

Retroviral-mediated transfer and amplification of a functional human factor VIII gene

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12 December 2020

The effect of thrombin on the complex between factor VIII and von Willebrand factor

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12 December 2020

Protein dissociation from GRP78 and secretion are blocked by depletion of cellular ATP levels

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12 December 2020

Association of the factor VIII light chain with von Willebrand factor

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12 December 2020

The activation and inactivation of human factor VIII by thrombin: effect of inhibitors of thrombin

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12 December 2020

Studies of a mechanism inhibiting the initiation of the extrinsic pathway of coagulation

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12 December 2020

The role of phospholipid and factor VIIIa in the activation of bovine factor X

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12 December 2020

Purified human factor VIII procoagulant protein: comparative hemostatic response after infusions into hemophilic and von Willebrand disease dogs

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12 December 2020

Rat gene encoding the 78-kDa glucose-regulated protein GRP78: its regulatory sequences and the effect of protein glycosylation on its expression.

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12 December 2020

Purification of human factor VIII:C and its characterization by Western blotting using monoclonal antibodies

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12 December 2020

The binding of 35S-labeled recombinant factor VIII to activated and unactivated human platelets.

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12 December 2020

Generation of active coagulation factor VIII from isolated subunits

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12 December 2020

Human factor VIIIa subunit structure. Reconstruction of factor VIIIa from the isolated A1/A3-C1-C2 dimer and A2 subunit

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12 December 2020

Mutations of factor VIII cleavage sites in hemophilia A.

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12 December 2020

Proteolytic processing of human factor VIII. Correlation of specific cleavages by thrombin, factor Xa, and activated protein C with activation and inactivation of factor VIII coagulant activity

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12 December 2020

The active site of blood coagulation factor Xa. Its distance from the phospholipid surface and its conformational sensitivity to components of the prothrombinase complex

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12 December 2020

Localization of factor VIIIC: antigen in guinea-pig tissues and isolated liver cell fractions.

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12 December 2020

Blood coagulation factors V and VIII: structural and functional similarities and their relationship to hemorrhagic and thrombotic disorders

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12 December 2020

Hemophilia: role of organ homografts

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12 December 2020

Properties of the factor Xa binding site on human platelets

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12 December 2020

Factor VIII binds to von Willebrand factor via its Mr-80,000 light chain

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12 December 2020

A large region (approximately equal to 95 kDa) of human factor VIII is dispensable for in vitro procoagulant activity

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12 December 2020

Antihemophilic globulin assay following plasma infusions in hemophilia

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12 December 2020

Sequence and expression of the discoidin I gene family in Dictyostelium discoideum

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12 December 2020

The relationship of N-linked glycosylation and heavy chain-binding protein association with the secretion of glycoproteins

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12 December 2020

Inactivation of human factor VIII by activated protein C. Cofactor activity of protein S and protective effect of von Willebrand factor

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12 December 2020

Reconstitution of human factor VIII from isolated subunits

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12 December 2020

Synthesis, processing, and secretion of recombinant human factor VIII expressed in mammalian cells

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12 December 2020

An Hsp70-like protein in the ER: identity with the 78 kd glucose-regulated protein and immunoglobulin heavy chain binding protein

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12 December 2020

Structure of human factor VIII

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12 December 2020

Proteolytic requirements for thrombin activation of anti-hemophilic factor (factor VIII)

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12 December 2020

Cofactor proteins in the assembly and expression of blood clotting enzyme complexes

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12 December 2020

Stabilization of thrombin-activated porcine factor VIII:C by factor IXa phospholipid

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12 December 2020

Liver transplantation in hemophilia A

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12 December 2020

Detection of factor X activation in humans

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12 December 2020

Liver transplantation in a hemophiliac

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12 December 2020

Distribution of factor VIII mRNA and antigen in human liver and other tissues

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12 December 2020

Deficiency of protein C in congenital thrombotic disease

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12 December 2020

Molecular cloning of a cDNA encoding human antihaemophilic factor

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12 December 2020

Heterogeneity in the tyrosine sulfation of Chinese hamster ovary cell produced recombinant FVIII.

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12 December 2020

The presence of malfolded proteins in the endoplasmic reticulum signals the induction of glucose-regulated proteins

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12 December 2020

The lipoprotein-associated coagulation inhibitor that inhibits the factor VII-tissue factor complex also inhibits factor Xa: insight into its possible mechanism of action

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12 December 2020

Factor V is a substrate for the transamidase factor XIIIa

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12 December 2020

Generation of prothrombin-converting activity and the exposure of phosphatidylserine at the outer surface of platelets

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12 December 2020

An immunogenic region within residues Val1670-Glu1684 of the factor VIII light chain induces antibodies which inhibit binding of factor VIII to von Willebrand factor

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12 December 2020

Heavy chain binding protein recognizes incompletely disulfide-bonded forms of vesicular stomatitis virus G protein

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12 December 2020

Stoichiometry of the porcine factor VIII-von Willebrand factor association

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12 December 2020

Structure-function relationships of factor VIII elucidated through recombinant DNA technology

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12 December 2020

Characterization of recombinant human factor VIII

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12 December 2020

Construction and characterization of an active factor VIII variant lacking the central one-third of the molecule

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12 December 2020

Survival of 125iodine-labeled Factor VIII in normals and patients with classic hemophilia. Observations on the heterogeneity of human Factor VIII

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12 December 2020

HEMOPHILIA. II. SOME PROPERTIES OF A SUBSTANCE OBTAINED FROM NORMAL HUMAN PLASMA EFFECTIVE IN ACCELERATING THE COAGULATION OF HEMOPHILIC BLOOD.

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12 December 2020

Proteolytic inactivation of human factor VIII procoagulant protein by activated human protein C and its analogy with factor V.

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12 December 2020

Plasma factor VIII synthesis and control as revealed by canine organ transplantation

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12 December 2020

Subunit structure of thrombin-activated porcine factor VIII

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12 December 2020

Differential proteolytic activation of factor VIII-von Willebrand factor complex by thrombin

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12 December 2020

Expression, purification, and characterization of recombinant gamma-carboxylated factor IX synthesized in Chinese hamster ovary cells

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12 December 2020

Thrombin proteolysis of purified factor viii procoagulant protein: correlation of activation with generation of a specific polypeptide.

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12 December 2020

Stabilization of factor VIII in plasma by the von Willebrand factor. Studies on posttransfusion and dissociated factor VIII and in patients with von Willebrand's disease

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12 December 2020

Human factor VIII procoagulant activity and phospholipid interaction

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12 December 2020

Increased synthesis of secreted proteins induces expression of glucose-regulated proteins in butyrate-treated Chinese hamster ovary cells

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12 December 2020

Characterization of the human factor VIII procoagulant protein with a heterologous precipitating antibody

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12 December 2020

Expression of active human factor VIII from recombinant DNA clones

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12 December 2020

The effect of plasma von Willebrand factor on the binding of human factor VIII to thrombin-activated human platelets

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12 December 2020

Protein C deficiency in a Dutch family with thrombotic disease

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12 December 2020

Factor Va-dependent binding of factor Xa to human platelets

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12 December 2020

Expression and characterization of human antithrombin III synthesized in mammalian cells

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12 December 2020

Localization of a factor VIII binding domain on a 34 kilodalton fragment of the N-terminal portion of von Willebrand factor

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12 December 2020

Response to infusions of polyelectrolyte fractionated human factor VIII concentrate in human haemophilia A and von Willebrand's disease

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12 December 2020

A major factor VIII binding domain resides within the amino-terminal 272 amino acid residues of von Willebrand factor

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12 December 2020

A canine model of hemophilic (factor VIII:C deficiency) bleeding

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12 December 2020

Subunit structure of thrombin-activated human factor VIIIa

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12 December 2020

Monoclonal antibodies to porcine factor VIII coagulant and their use in the isolation of active coagulant protein

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12 December 2020

Identifiers

DOI

10.1007/BF01703248

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20 August 2017

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