Biology of insulin-like factor 3 in human reproduction. (Q37426207)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19329805%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

review article

1 reference

title

Biology of insulin-like factor 3 in human reproduction (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19329805%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

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1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19329805%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

Ravinder Anand-Ivell

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19329805%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

author name string

Richard Ivell

series ordinal

1

1 reference

20 August 2017

Ravinder Anand-Ivell

series ordinal

2

1 reference

20 August 2017

publication date

28 March 2009

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19329805%20AND%20SRC:MED&resulttype=core&format=json

Human Reproduction Update

25 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19329805%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

volume

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19329805%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

issue

4

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25 January 2020

page(s)

463-476

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19329805%20AND%20SRC:MED&resulttype=core&format=json

Expression of the insulin-like peptide 3 (INSL3) hormone-receptor (LGR8) system in the testis.

25 January 2020

cites work

1 reference

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Peripheral INSL3 concentrations decline with age in a large population of Australian men.

21 January 2018

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Relaxin signalling in THP-1 cells uses a novel phosphotyrosine-dependent pathway

21 January 2018

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Insulin-like factor 3 levels in amniotic fluid of human male fetuses.

21 January 2018

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Relaxin signalling links tyrosine phosphorylation to phosphodiesterase and adenylyl cyclase activity

21 January 2018

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Relaxin-like factor gene is highly expressed in the bovine ovary of the cycle and pregnancy: sequence and messenger ribonucleic acid analysis

21 January 2018

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International Union of Pharmacology LVII: recommendations for the nomenclature of receptors for relaxin family peptides

21 January 2018

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Insulin-like factor 3 serum levels in 135 normal men and 85 men with testicular disorders: relationship to the luteinizing hormone-testosterone axis

21 January 2018

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The effects of gonadotropin suppression and selective replacement on insulin-like factor 3 secretion in normal adult men.

21 January 2018

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Insulin-like factor 3 levels in cord blood and serum from children: effects of age, postnatal hypothalamic-pituitary-gonadal axis activation, and cryptorchidism

21 January 2018

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Insulin-like factor 3 levels in second-trimester amniotic fluid

21 January 2018

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T222P mutation of the insulin-like 3 hormone receptor LGR8 is associated with testicular maldescent and hinders receptor expression on the cell surface membrane

21 January 2018

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The mode of interaction of the relaxin-like factor (RLF) with the leucine-rich repeat G protein-activated receptor 8.

21 January 2018

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The relaxin-like factor is a hormone

21 January 2018

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Solution structure of a conformationally restricted fully active derivative of the human relaxin-like factor

21 January 2018

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Structural organization of the porcine and human genes coding for a Leydig cell-specific insulin-like peptide (LEY I-L) and chromosomal localization of the human gene (INSL3)

21 January 2018

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Analogs of insulin-like peptide 3 (INSL3) B-chain are LGR8 antagonists in vitro and in vivo.

21 January 2018

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Analytical and physiological factors affecting the interpretation of serum testosterone concentration in men.

21 January 2018

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Novel mutations involving the INSL3 gene associated with cryptorchidism

21 January 2018

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No association between T222P/LGR8 mutation and cryptorchidism in the Moroccan population

21 January 2018

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Insulin-like factor 3 gene mutations in testicular dysgenesis syndrome: clinical and functional characterization.

21 January 2018

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Mutations in the insulin-like factor 3 receptor are associated with osteoporosis

21 January 2018

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Genetic alterations associated with cryptorchidism

21 January 2018

1 reference

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Relaxin family peptide receptors Rxfp1 and Rxfp2: mapping of the mRNA and protein distribution in the reproductive tract of the male rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMP011

A novel circulating hormone of testis origin in humans

21 January 2018

1 reference

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Role of hormones, genes, and environment in human cryptorchidism

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMP011

Insulin-like factor 3: a new circulating hormone related to luteinizing hormone-dependent ovarian hyperandrogenism in the polycystic ovary syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMP011

Relaxin signalling in primary cultures of human myometrial cells.

21 January 2018

1 reference

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Relaxin-like factor (RLF) mRNA expression in the fallow deer

21 January 2018

1 reference

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Cellular localization of human relaxin-like factor in the cyclic endometrium and placenta

21 January 2018

1 reference

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Seasonal expression of INSL3 and Lgr8/Insl3 receptor transcripts indicates variable differentiation of Leydig cells in the roe deer testis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMP011

Dynamic changes in the expression of relaxin-like factor (INSL3), cholesterol side-chain cleavage cytochrome p450, and 3beta-hydroxysteroid dehydrogenase in bovine ovarian follicles during growth and atresia

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMP011

The molecular basis of cryptorchidism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMP011

Differentiation-dependent expression of 17beta-hydroxysteroid dehydrogenase, type 10, in the rodent testis: effect of aging in Leydig cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMP011

Immunoexpression of the relaxin receptor LGR7 in breast and uterine tissues of humans and primates

21 January 2018

1 reference

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Diverse signalling mechanisms used by relaxin in natural cells and tissues: the evolution of a "neohormone".

21 January 2018

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Cryptorchidism: an indicator of testicular dysgenesis?

21 January 2018

1 reference

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Paracrine regulation of mammalian oocyte maturation and male germ cell survival

21 January 2018

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Cloning, expression, and functional characterization of relaxin receptor (leucine-rich repeat-containing g protein-coupled receptor 7) splice variants from human fetal membranes

21 January 2018

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Expression of relaxin-like factor is down-regulated in human testicular Leydig cell neoplasia.

21 January 2018

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Canine relaxin-like factor: unique molecular structure and differential expression within reproductive tissues of the dog.

21 January 2018

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Molecular remodeling of members of the relaxin family during primate evolution

21 January 2018

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INSL3 ligand-receptor system in the equine testis

21 January 2018

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Murine relaxin-like factor promoter: functional characterization and regulation by transcription factors steroidogenic factor 1 and DAX-1.

21 January 2018

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The role of insulin 3, testosterone, Müllerian inhibiting substance and relaxin in rat gubernacular growth

21 January 2018

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INSL3/Leydig insulin-like peptide activates the LGR8 receptor important in testis descent

21 January 2018

1 reference

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Antagonistic effects of testosterone and the endocrine disruptor mono-(2-ethylhexyl) phthalate on INSL3 transcription in Leydig cells

21 January 2018

1 reference

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Intraadrenal adrenocorticotropin production in a case of bilateral macronodular adrenal hyperplasia causing Cushing's syndrome.

21 January 2018

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Identification of Relaxin-3/INSL7 as an Endogenous Ligand for the Orphan G-protein-coupled Receptor GPCR135

21 January 2018

1 reference

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Relaxin-3 in GABA projection neurons of nucleus incertus suggests widespread influence on forebrain circuits via G-protein-coupled receptor-135 in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMP011

Expression of insulin-like factor 3 protein in the rat testis during fetal and postnatal development and in relation to cryptorchidism induced by in utero exposure to di (n-Butyl) phthalate

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMP011

Splice variants of the relaxin and INSL3 receptors reveal unanticipated molecular complexity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMP011

Cryptorchidism in mice mutant for Insl3

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMP011

The leucine-rich repeat-containing G protein-coupled receptor 8 gene T222P mutation does not cause cryptorchidism

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMP011

The expression of the RLF/INSL3 gene is reduced in Leydig cells of the aging rat testis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMP011

Age at surgery for undescended testis and risk of testicular cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMP011

The orphan nuclear receptor NR4A1 regulates insulin-like 3 gene transcription in Leydig cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMP011

Characterization of novel splice variants of LGR7 and LGR8 reveals that receptor signaling is mediated by their unique low density lipoprotein class A modules

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMP011

Directed overexpression of insulin in Leydig cells causes a progressive loss of germ cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMP011

Reproductive hormone reference intervals for healthy fertile young men: evaluation of automated platform assays

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMP011

Testicular dysgenesis syndrome: an increasingly common developmental disorder with environmental aspects

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMP011

Cooperative binding of insulin-like Peptide 3 to a dimeric relaxin family peptide receptor 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMP011

The aging male hypothalamic-pituitary-gonadal axis: pulsatility and feedback

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMP011

Epidemiology and pathogenesis of cryptorchidism

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMP011

Serum insulin-like factor 3 levels during puberty in healthy boys and boys with Klinefelter syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMP011

The evolution of the relaxin peptide family and their receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMP011

Evolution of the relaxin-like peptide family

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMP011

Differential splicing and expression of the relaxin-like factor gene in reproductive tissues of the marmoset monkey (Callithrix jacchus).

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMP011

Bioactivity of recombinant prorelaxin from the marmoset monkey

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMP011

Transcription of the Leydig insulin-like gene is mediated by steroidogenic factor-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMP011

Targeted disruption of the Insl3 gene causes bilateral cryptorchidism

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMP011

Elevated End-of-Treatment Serum INSL3 Is Associated With Failure to Completely Suppress Spermatogenesis in Men Receiving Male Hormonal Contraception

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMP011

Changes in Serum Insulin-Like Factor 3 during Normal Male Puberty

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMP011

21 January 2018

Identifiers

DOI

10.1093/HUMUPD/DMP011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19329805%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

1 reference