Neuroprotective and cardioprotective conopeptides: an emerging class of drug leads. (Q37427566)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19333868%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

review article

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title

Neuroprotective and cardioprotective conopeptides: an emerging class of drug leads (English)

1 reference

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25 January 2020

3

Baldomero M Olivera

1 reference

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25 January 2020

1

Vernon D Twede

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25 January 2020

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19333868%20AND%20SRC:MED&resulttype=core&format=json

George Miljanich

2

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25 January 2020

Grzegorz Bulaj

series ordinal

4

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25 January 2020

publication date

1 March 2009

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Current Opinion in Drug Discovery and Development

25 January 2020

published in

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25 January 2020

volume

12

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25 January 2020

issue

2

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25 January 2020

page(s)

231-239

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Structure, dynamics, and selectivity of the sodium channel blocker mu-conotoxin SIIIA.

25 January 2020

cites work

1 reference

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Powerful antinociceptive effects of the cone snail venom-derived subtype-selective NMDA receptor antagonists conantokins G and T.

23 August 2017

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Conantokin-L, a new NMDA receptor antagonist: determinants for anticonvulsant potency.

23 August 2017

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Intrathecal CGX-1007 is neuroprotective in a rat model of focal cerebral ischemia

23 August 2017

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Conantokin G is an NR2B-selective competitive antagonist of N-methyl-D-aspartate receptors

23 August 2017

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The block of Shaker K+ channels by kappa-conotoxin PVIIA is state dependent

23 August 2017

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kappa-Conotoxin PVIIA is a peptide inhibiting the shaker K+ channel

23 August 2017

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A selective N-type calcium channel antagonist protects against neuronal loss after global cerebral ischemia

23 August 2017

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A sleep-inducing peptide from Conus geographus venom

23 August 2017

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Conantokin-T. A gamma-carboxyglutamate containing peptide with N-methyl-d-aspartate antagonist activity

23 August 2017

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Treatment with the snail peptide CGX-1007 reduces DNA damage and alters gene expression of c-fos and bcl-2 following focal ischemic brain injury in rats

23 August 2017

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The binding of kappa-Conotoxin PVIIA and fast C-type inactivation of Shaker K+ channels are mutually exclusive

6 September 2017

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The amino acid residue at sequence position 5 in the conantokin peptides partially governs subunit-selective antagonism of recombinant N-methyl-D-aspartate receptors

14 September 2017

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A novel conus peptide ligand for K+ channels

28 September 2017

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Improvement in mitochondrial dysfunction as a new surrogate efficiency measure for preclinical trials: dose-response and time-window profiles for administration of the calcium channel blocker Ziconotide in experimental brain injury

26 June 2018

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Effects of an N-type calcium channel antagonist (SNX 111; Ziconotide) on calcium-45 accumulation following fluid-percussion injury

26 June 2018

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Continuing postischemic neuronal death in CA1: influence of ischemia duration and cytoprotective doses of NBQX and SNX-111 in rats.

26 June 2018

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Expression of N-methyl-D-aspartate receptor subunit mRNA in the human brain: mesencephalic dopaminergic neurons

26 June 2018

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26 June 2018

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Time-course and treatment response with SNX-111, an N-type calcium channel blocker, in a rodent model of focal cerebral ischemia using diffusion-weighted MRI.

26 June 2018

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26 June 2018

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26 June 2018

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26 June 2018

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2 September 2018

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2 September 2018

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A novel conotoxin inhibitor of Kv1.6 channel and nAChR subtypes defines a new superfamily of conotoxins.

2 September 2018

1 reference

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Structural and functional diversities among mu-conotoxins targeting TTX-resistant sodium channels.

2 September 2018

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Effects of delayed intrathecal infusion of an NMDA receptor antagonist on ischemic injury and peri-infarct depolarizations.

2 September 2018

1 reference

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Postischemic administration of CGX-1051, a peptide from cone snail venom, reduces infarct size in both rat and dog models of myocardial ischemia and reperfusion

2 September 2018

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Novel conotoxins from Conus striatus and Conus kinoshitai selectively block TTX-resistant sodium channels.

2 September 2018

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Electrostatic recognition and induced fit in the kappa-PVIIA toxin binding to Shaker potassium channel.

2 September 2018

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Conkunitzin-S1 is the first member of a new Kunitz-type neurotoxin family. Structural and functional characterization

2 September 2018

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Identification of a novel pharmacophore for peptide toxins interacting with K+ channels.

2 September 2018

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Neuroprotection in the rat lateral fluid percussion model of traumatic brain injury by SNX-185, an N-type voltage-gated calcium channel blocker

2 September 2018

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KappaM-conotoxin RIIIK, structural and functional novelty in a K+ channel antagonist

2 September 2018

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Identification of a mammalian target of kappaM-conotoxin RIIIK.

2 September 2018

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CGX-1051, a peptide from Conus snail venom, attenuates infarction in rabbit hearts when administered at reperfusion

2 September 2018

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Neurobehavioral protection by the neuronal calcium channel blocker ziconotide in a model of traumatic diffuse brain injury in rats

2 September 2018

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In vitro and in vivo characterization of conantokin-R, a selective NMDA receptor antagonist isolated from the venom of the fish-hunting snail Conus radiatus.

2 September 2018

1 reference

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NMDA-receptor antagonist requirements in conantokin-G.

2 September 2018

1 reference

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Mitochondrial dysfunction after experimental traumatic brain injury: combined efficacy of SNX-111 and U-101033E.

2 September 2018

1 reference

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Expression of N-methyl-D-aspartate receptor subunit mRNAs in the human brain: striatum and globus pallidus.

2 September 2018

1 reference

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SNX-111, a novel, presynaptic N-type calcium channel antagonist, is neuroprotective against focal cerebral ischemia in rabbits.

2 September 2018

1 reference

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Sympatholysis after neuron-specific, N-type, voltage-sensitive calcium channel blockade: first demonstration of N-channel function in humans.

2 September 2018

1 reference

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The omega-conopeptide SNX-111, an N-type calcium channel blocker, dramatically ameliorates brain damage due to transient focal ischaemia.

2 September 2018

1 reference

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Bioavailability of Ziconotide in brain: influx from blood, stability, and diffusion

2 September 2018

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12 December 2020

Neuroprotective efficacy and therapeutic window of the high-affinity N-methyl-D-aspartate antagonist conantokin-G: in vitro (primary cerebellar neurons) and in vivo (rat model of transient focal brain ischemia) studies

1 reference

12 December 2020

Single amino acid substitutions in kappa-conotoxin PVIIA disrupt interaction with the shaker K+ channel

1 reference

12 December 2020

Strategy for rapid immobilization of prey by a fish-hunting marine snail

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12 December 2020

Polyamine-like actions of peptides derived from conantokin-G, an N-methyl-D-aspartate (NMDA) antagonist

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12 December 2020

A selective N-type Ca(2+)-channel blocker prevents CA1 injury 24 h following severe forebrain ischemia and reduces infarction following focal ischemia

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12 December 2020

A selective N-type calcium channel antagonist reduces extracellular glutamate release and infarct volume in focal cerebral ischemia

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12 December 2020

The neuroprotective effects of intrathecal administration of the selective N-type calcium channel blocker ziconotide in a rat model of spinal ischemia

1 reference

12 December 2020

Identifiers

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19333868%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

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