Development and use of sulodexide in vascular diseases: implications for treatment (Q37427653)

20 August 2017

1 reference

18 November 2019

Development and use of sulodexide in vascular diseases: implications for treatment (English)

1 reference

20 August 2017

1 reference

18 November 2019

1 reference

18 November 2019

Sergio Coccheri

1

1 reference

20 August 2017

Ferdinando Mannello

series ordinal

2

1 reference

20 August 2017

language of work or name

English

0 references

publication date

24 December 2013

3 references

Drug Design, Development and Therapy

20 August 2017

17 June 2019

18 November 2019

3 references

20 August 2017

17 June 2019

18 November 2019

8

1 reference

20 August 2017

49-65

1 reference

Creative Commons Attribution-NonCommercial

20 August 2017

2 references

17 June 2019

18 November 2019

on focus list of Wikimedia project

ScienceSource

0 references

cites work

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Treatment of 5/6 nephrectomy rats with sulodexide: a novel therapy for chronic renal failure

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Sulodexide in the treatment of chronic venous disease

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Sulodexide fails to demonstrate renoprotection in overt type 2 diabetic nephropathy

23 August 2017

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Anti-proteinuric effect of sulodexide in immunoglobulin a nephropathy

23 August 2017

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The care of patients with varicose veins and associated chronic venous diseases: clinical practice guidelines of the Society for Vascular Surgery and the American Venous Forum

23 August 2017

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23 August 2017

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23 August 2017

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Effect of sulodexide on endothelial glycocalyx and vascular permeability in patients with type 2 diabetes mellitus

23 August 2017

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Vascular Dermatan Sulfate and Heparin Cofactor II

23 August 2017

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Sulodexide ameliorates early but not late kidney disease in models of radiation nephropathy and diabetic nephropathy

23 August 2017

1 reference

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Heparan sulfate proteoglycans: structure, protein interactions and cell signaling

23 August 2017

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Comparative anticoagulant and platelet modulatory effects of enoxaparin and sulodexide

23 August 2017

1 reference

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Management of tinnitus: oral treatment with melatonin and sulodexide.

23 August 2017

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Aspirin in the primary and secondary prevention of vascular disease: collaborative meta-analysis of individual participant data from randomised trials

23 August 2017

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Chondroitin sulphate: a complex molecule with potential impacts on a wide range of biological systems

23 August 2017

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The structure of glycosaminoglycans and their interactions with proteins.

23 August 2017

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The biological role of chondroitin sulfate in cancer and chondroitin-based anticancer agents

23 August 2017

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Antithrombotic therapy for venous thromboembolic disease: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition).

23 August 2017

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Pathogenesis of primary chronic venous disease: Insights from animal models of venous hypertension

23 August 2017

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The role of sulodexide in the treatment of diabetic nephropathy

23 August 2017

1 reference

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Approaches to prevention of cardiovascular complications and events in diabetes mellitus

23 August 2017

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Sulodexide: a renewed interest in this glycosaminoglycan

23 August 2017

1 reference

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23 August 2017

Chronic venous disease

1 reference

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The post-thrombotic syndrome: progress and pitfalls

23 August 2017

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Chronic venous disease and the leukocyte-endothelium interaction: from symptoms to ulceration

23 August 2017

1 reference

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Unfractionated heparin, low molecular weight heparins, and pentasaccharide: basic mechanism of actions, pharmacology, and clinical use.

23 August 2017

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Revision of the CEAP classification for chronic venous disorders: consensus statement

23 August 2017

1 reference

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The effect of insulin and sulodexide (Vessel Due F) on diabetic foot syndrome: pilot study in elderly patients

23 August 2017

1 reference

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Hemorheology and tissue oxygenation in hypertensives with lipoidoproteinosis and peripheral occlusive arterial disease (POAD) treated with sulodexide and pravastatine and evaluated with laser assisted optical rotational red cell analyzer [...]

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879015

Chronic venous disorders of the leg: epidemiology, outcomes, diagnosis and management. Summary of an evidence-based report of the VEINES task force. Venous Insufficiency Epidemiologic and Economic Studies

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879015

Prevalence of varicose veins and chronic venous insufficiency in men and women in the general population: Edinburgh Vein Study

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879015

Review of pharmacodynamics, pharmacokinetics, and therapeutic properties of sulodexide

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879015

A new mechanism of action of sulodexide in diabetic nephropathy: inhibits heparanase-1 and prevents FGF-2-induced renal epithelial-mesenchymal transition.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879015

Use of sulodexide in patients with peripheral vascular disease

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879015

Nephroprotective action of glycosaminoglycans: why the pharmacological properties of sulodexide might be reconsidered

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879015

Protective effect of sulodexide on podocyte injury in adriamycin nephropathy rats

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879015

The epidemiology of peripheral arterial disease: importance of identifying the population at risk

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879015

Vascular dementia Italian sulodexide study (VA.D.I.S.S.). Clinical and biological results.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879015

Inhibition of neointimal proliferation of rat carotid artery by sulodexide

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879015

Induction of experimental arterial occlusive thrombi in rats

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879015

Double-blind multicenter trial on a new medium molecular weight glycosaminoglycan. Current therapeutic effects and perspectives for clinical use.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879015

Sulodexide improves renal function through reduction of vascular endothelial growth factor in type 2 diabetic rats.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879015

Extended treatment of venous thromboembolism

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879015

Sulodexide may alleviate neointimal hyperplasia by inhibiting angiopoietin‑2 in an arteriovenous fistula model

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879015

Sulodexide prevents peripheral nerve damage in streptozotocin induced diabetic rats.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879015

Effect of sulodexide on aortic vasodilation capacity and associated morphological changes in rats with streptozotocin-induced diabetes

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879015

Full-length TFPI release by heparinoid sulodexide

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879015

Efficacy of low-dose oral sulodexide in the management of diabetic nephropathy.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879015

Intravenous and oral sulodexide versus coagulation activation markers in humans.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879015

[Renal protective effects of sulodexide in diabetic rats and its anti-oxidative mechanism].

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879015

Sulodexide suppresses inflammation in human endothelial cells and prevents glucose cytotoxicity

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879015

Effect of sulodexide on plasma transforming growth factor-beta1 in healthy volunteers.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879015

Sulodexide improves endothelial dysfunction in streptozotocin-induced diabetes in rats.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879015

Distribution and prevalence of reflux in the superficial and deep venous system in the general population--results from the Bonn Vein Study, Germany.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879015

Effects of sulodexide in patients with type 2 diabetes and persistent albuminuria

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879015

Wound bed score and its correlation with healing of chronic wounds.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879015

A study on the safety, efficacy, and efficiency of sulodexide compared with acenocoumarol in secondary prophylaxis in patients with deep venous thrombosis

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879015

Prevention of recurrent deep venous thrombosis with sulodexide: the SanVal registry

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879015

Additive thrombin inhibition by fast moving heparin and dermatan sulfate explains the anticoagulant effect of sulodexide, a natural mixture of glycosaminoglycans

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879015

Sulodexide in the treatment of intermittent claudication. Results of a randomized, double-blind, multicentre, placebo-controlled study

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879015

Randomised, double blind, multicentre, placebo controlled study of sulodexide in the treatment of venous leg ulcers.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879015

Oral sulodexide reduces albuminuria in microalbuminuric and macroalbuminuric type 1 and type 2 diabetic patients: the Di.N.A.S. randomized trial

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879015

Predictive value of D-dimer test for recurrent venous thromboembolism after anticoagulation withdrawal in subjects with a previous idiopathic event and in carriers of congenital thrombophilia

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879015

Treatment of venous leg ulcers with sulodexide

2 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879015

Sulodexide for Kidney Protection in Type 2 Diabetes Patients With Microalbuminuria: A Randomized Controlled Trial

2 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879015

Glycosaminoglycan origin and structure revealed by multivariate analysis of NMR and CD spectra

3 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879015

Impaired fibrinolytic response to increased thrombin activation in type 1 diabetes mellitus: effects of the glycosaminoglycan sulodexide

3 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879015

Interaction between glycosaminoglycans, platelets, and leukocytes

3 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879015

Bleeding complications of oral anticoagulant treatment: an inception-cohort, prospective collaborative study (ISCOAT). Italian Study on Complications of Oral Anticoagulant Therapy

3 December 2018

1 reference

12 December 2020

Prevention of thrombus formation and growth by antithrombin III and heparin cofactor II-dependent thrombin inhibitors: importance of heparin cofactor II

1 reference

12 December 2020

Lowering of plasma viscosity by the oral administration of the glycosaminoglycan sulodexide in patients with peripheral vascular disease

1 reference

12 December 2020

Antithrombotic and thrombolytic activity of sulodexide in rats

1 reference

12 December 2020

Controlled clinical trial on the efficacy and safety of oral sulodexide in patients with peripheral occlusive arterial disease

1 reference

12 December 2020

Comparative pharmacologic profile of a glycosaminoglycan mixture, Sulodexide, and a chemically modified heparin derivative, Suleparoide

1 reference

12 December 2020

Pharmacological actions of sulodexide

1 reference

12 December 2020

Dermatan sulphate for the prevention of postoperative venous thromboembolism in patients with cancer. DOS (Dermatan sulphate in Oncologic Surgery) Study Group

1 reference

12 December 2020

Game not over for sulodexide

1 reference

12 December 2020

Pharmacological treatment in patients with chronic venous disease

1 reference

12 December 2020

A placebo-controlled, double-blind study of mesoglycan in the treatment of chronic venous ulcers

1 reference

12 December 2020

Effect of heparin-like compounds on the in vitro proliferation and protein synthesis of various cell types

1 reference

12 December 2020

Organ glycosaminoglycan distribution after intravenous and oral administration in rats

1 reference

12 December 2020

Human pharmacokinetics of glycosaminoglycans using deuterium-labeled and unlabeled substances: evidence for oral absorption

1 reference

12 December 2020

Antithrombotic activity of a glycosaminoglycan (sulodexide) in rats

1 reference

12 December 2020

Meta-analysis of some results of clinical trials on sulodexide therapy in peripheral occlusive arterial disease

1 reference

12 December 2020

Surrogate versus clinical end points and venture capital companies: the doubts of a clinician

1 reference

12 December 2020

Discounting the efficacy of sulodexide in diabetic nephropathy is premature

1 reference

12 December 2020

Antithrombotic activity of dermatan sulphates, heparins and their combination in an animal model of arterial thrombosis

1 reference

12 December 2020

Sulodexide induces hepatocyte growth factor release in humans

1 reference

12 December 2020

Double-blind, double-dummy, randomized, multi-centre clinical assessment of the efficacy, tolerability and dose-effect relationship of sulodexide in chronic venous insufficiency

1 reference

12 December 2020

Sulodexide and the microcirculatory component in microphlebopathies

1 reference

12 December 2020

IPO-V2: a prospective, multicenter, randomized, comparative clinical investigation of the effects of sulodexide in preventing cardiovascular accidents in the first year after acute myocardial infarction

1 reference

12 December 2020

Sulodexide for diabetic nephropathy: another one bites the dust

1 reference

12 December 2020

Glycosaminoglycan sulodexide inhibition of MMP-9 gelatinase secretion and activity: possible pharmacological role against collagen degradation in vascular chronic diseases

1 reference

12 December 2020

Identifiers

DOI

10.2147/DDDT.S6762

1 reference

20 August 2017

1 reference

20 August 2017

PubMed publication ID

24391440

1 reference