Spironolactone attenuates experimental uremic cardiomyopathy by antagonizing marinobufagenin (Q37438192)

20 August 2017

Spironolactone attenuates experimental uremic cardiomyopathy by antagonizing marinobufagenin (English)

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20 August 2017

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Jiang Tian

1

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20 August 2017

Amjad Shidyak

2

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20 August 2017

Sankaridrug M Periyasamy

3

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20 August 2017

Steven Haller

4

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20 August 2017

Mohamed Taleb

5

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20 August 2017

Nasser El-Okdi

6

1 reference

20 August 2017

Jihad Elkareh

7

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20 August 2017

Shalini Gupta

8

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20 August 2017

Sabry Gohara

9

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20 August 2017

Olga V Fedorova

10

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20 August 2017

Christopher J Cooper

11

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20 August 2017

Zijian Xie

12

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20 August 2017

Deepak Malhotra

13

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20 August 2017

Alexei Y Bagrov

14

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20 August 2017

Joseph I Shapiro

15

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20 August 2017

language of work or name

English

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publication date

2 November 2009

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20 August 2017

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20 August 2017

54

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20 August 2017

6

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20 August 2017

1313-1320

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Marinobufagenin induces increases in procollagen expression in a process involving protein kinase C and Fli-1: implications for uremic cardiomyopathy

20 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783263

Hypertrophy and fibrosis in the cardiomyopathy of uremia--beyond coronary heart disease

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783263

Endogenous sodium pump inhibitors and age-associated increases in salt sensitivity of blood pressure in normotensives

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783263

Partial nephrectomy as a model for uremic cardiomyopathy in the mouse

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783263

Significance of late gadolinium enhancement in cardiovascular magnetic resonance imaging (CMR).

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783263

Aldosterone blockade: an emerging strategy for abrogating progressive renal disease

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783263

Minireview: aldosterone and the cardiovascular system: genomic and nongenomic effects

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783263

Effect of MR blockade on collagen formation and cardiovascular disease with a specific emphasis on heart failure

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783263

Aldosterone-induced organ damage: plasma aldosterone level and inappropriate salt status

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783263

Mineralocorticoid receptors and pathophysiological roles for aldosterone in the cardiovascular system.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783263

Cardiac fibrosis as a cause of diastolic dysfunction

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783263

Aldosterone and myocardial fibrosis in heart failure

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783263

Induction of cardiac fibrosis by aldosterone

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783263

The effect of spironolactone on morbidity and mortality in patients with severe heart failure. Randomized Aldactone Evaluation Study Investigators

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783263

Parathyroid hormone, vitamin D, and cardiovascular disease in chronic renal failure.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783263

Antagonism of the renin-angiotensin-aldosterone system and collagen metabolism in cardiac fibroblasts.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783263

Role of aldosterone in the remnant kidney model in the rat.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783263

Species differences in the metabolism and disposition of spironolactone

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783263

Identification of a pool of non-pumping Na/K-ATPase

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783263

Steroids, hypertension and cardiac fibrosis

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783263

Cardiac effects of antikaliuretic diuretics-clinical and biochemical investigation (author's transl)

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783263

Looking beyond the dogma of genomic steroid action: insights and facts of the 1990s

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783263

Spironolactone improves carotid artery fibrosis and distensibility in rat post-ischaemic heart failure

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783263

Aldosterone, salt and cardiac fibrosis

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783263

Cardiac disease in chronic uremia: pathogenesis

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783263

Increase in the basal tone of guinea pig thoracic aorta induced by ouabain is inhibited by spironolactone canrenone and potassium canrenoate

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783263

Rapid effects of mineralocorticoids on sodium-proton exchanger: genomic or nongenomic pathway?

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783263

Effect of spironolactone on left ventricular mass and aortic stiffness in early-stage chronic kidney disease: a randomized controlled trial.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783263

Mineralocorticoid receptor antagonism attenuates cardiac hypertrophy and prevents oxidative stress in uremic rats

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783263

Effects of spironolactone during an angiotensin II receptor blocker treatment on the left ventricular mass reduction in hypertensive patients with concentric left ventricular hypertrophy

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783263

Central role for the cardiotonic steroid marinobufagenin in the pathogenesis of experimental uremic cardiomyopathy

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783263

Salt loading induces redistribution of the plasmalemmal Na/K-ATPase in proximal tubule cells

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783263

Antiproteinuric effects of mineralocorticoid receptor blockade in patients with chronic renal disease

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783263

Mechanisms for aldosterone and spironolactone-induced positive inotropic actions in the rat heart

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783263

Effect of canrenone on the digitalis site of Na+/K(+)-ATPase in human placental membranes and in erythrocytes.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783263

Therapeutic benefit of spironolactone in experimental chronic cyclosporine A nephrotoxicity.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783263

Rapid effects of aldosterone and spironolactone in the isolated working rat heart

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783263

Temporal differences in fibroblast proliferation and phenotype expression in response to chronic administration of angiotensin II or aldosterone.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783263

Canrenone as a partial agonist at the digitalis receptor site of sodium-potassium-activated adenosine triphosphatase.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783263

Effectiveness of spironolactone added to an angiotensin-converting enzyme inhibitor and a loop diuretic for severe chronic congestive heart failure (the Randomized Aldactone Evaluation Study [RALES])

2 September 2018

1 reference

12 December 2020

Effect of chronic renal failure on cardiac contractile function, calcium cycling, and gene expression of proteins important for calcium homeostasis in the rat

1 reference

12 December 2020

Mode of spirolactone action: competitive inhibition of aldosterone binding to kidney mineralocorticoid receptors

1 reference

12 December 2020

Digitoxin poisoning: prevention by spironolactone

1 reference

12 December 2020

Conversion of spironolactone to canrenone and disposition kinetics of spironolactone and canrenoate-potassium in rats

1 reference

12 December 2020

Spironolactone- and Canrenone-Induced Changes in Hepatic (Na+, K+)ATPase Activity, Surface Membrane Cholesterol and Phospholipid, and Fluorescence Polarization in the Rat

1 reference

12 December 2020

The interaction of canrenone with the Na+,K+ pump in human red blood cells

1 reference

12 December 2020

Collagen metabolism in cultured adult rat cardiac fibroblasts: response to angiotensin II and aldosterone

1 reference

12 December 2020

Aldosterone and cardiac fibrosis: in vitro studies

1 reference

12 December 2020

Does Aldosterone-lnduced Cardiac Fibrosis Involve Direct Effects on Cardiac Fibroblasts?

1 reference

12 December 2020

Cardioprotective mechanisms of spironolactone associated with the angiotensin-converting enzyme/epidermal growth factor receptor/extracellular signal-regulated kinases, NAD(P)H oxidase/lectin-like oxidized low-density lipoprotein receptor-1, and Rho

1 reference

12 December 2020

Combined treatment with valsartan and spironolactone prevents cardiovascular remodeling in renovascular hypertensive rats

1 reference

12 December 2020

Enhanced aldosterone signaling in the early nephropathy of rats with metabolic syndrome: possible contribution of fat-derived factors

1 reference

12 December 2020

Marinobufagenin stimulates fibroblast collagen production and causes fibrosis in experimental uremic cardiomyopathy

1 reference

12 December 2020

Long-term mineralocorticoid receptor blockade reduces fibrosis and improves cardiac performance and coronary hemodynamics in elderly SHR

1 reference

12 December 2020

10.1161/HYPERTENSIONAHA.109.140038

Identifiers

DOI

1 reference

20 August 2017

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20 August 2017

PubMed publication ID

19884563

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