Curcumin eliminates oxidized LDL roles in activating hepatic stellate cells by suppressing gene expression of lectin-like oxidized LDL receptor-1. (Q37438687)

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scientific article published on 07 September 2009

Language	Label	Description	Also known as
English	Curcumin eliminates oxidized LDL roles in activating hepatic stellate cells by suppressing gene expression of lectin-like oxidized LDL receptor-1.	scientific article published on 07 September 2009

Statements

scholarly article

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

Curcumin eliminates oxidized LDL roles in activating hepatic stellate cells by suppressing gene expression of lectin-like oxidized LDL receptor-1. (English)

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

0 references

author name string

Qiaohua Kang

1

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

Anping Chen

2

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

publication date

7 September 2009

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

Laboratory Investigation

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

89

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

11

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

1275-1290

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

Association between circulating oxidized low-density lipoprotein and incidence of the metabolic syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783367

23 August 2017

Mechanisms of hepatic fibrogenesis

1 reference

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23 August 2017

Activation of peroxisome proliferator-activated receptor-gamma by curcumin blocks the signaling pathways for PDGF and EGF in hepatic stellate cells

1 reference

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Wnt signaling inside the nucleus

1 reference

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The first five years of the Wnt targetome

1 reference

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The lectin-like oxidized low-density-lipoprotein receptor: a pro-inflammatory factor in vascular disease

1 reference

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23 August 2017

Wnt antagonism inhibits hepatic stellate cell activation and liver fibrosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783367

23 August 2017

De novo synthesis of glutathione is a prerequisite for curcumin to inhibit hepatic stellate cell (HSC) activation

1 reference

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WNT/beta-catenin signaling in liver health and disease

1 reference

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Oxidative stress biology and cell injury during type 1 and type 2 diabetes mellitus

1 reference

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23 August 2017

Disruption of transforming growth factor-beta signaling by curcumin induces gene expression of peroxisome proliferator-activated receptor-gamma in rat hepatic stellate cells

1 reference

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23 August 2017

Anti-adipogenic regulation underlies hepatic stellate cell transdifferentiation

1 reference

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23 August 2017

Functional interaction between peroxisome proliferator-activated receptor gamma and beta-catenin

1 reference

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23 August 2017

Gene expression profile of quiescent and activated rat hepatic stellate cells implicates Wnt signaling pathway in activation

1 reference

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23 August 2017

Endothelial scavenger receptors

1 reference

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The epidemiology of nonalcoholic fatty liver disease in adults

1 reference

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23 August 2017

Lectin-like, oxidized low-density lipoprotein receptor-1 (LOX-1): a critical player in the development of atherosclerosis and related disorders

1 reference

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The inhibitory mechanism of curcumin and its derivative against beta-catenin/Tcf signaling

1 reference

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Functional genomic analysis of the Wnt-wingless signaling pathway

1 reference

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Regulation of PPARgamma activity during adipogenesis

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23 August 2017

1 reference

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Biological properties of curcumin-cellular and molecular mechanisms of action

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Quantitative reverse transcription-polymerase chain reaction to study mRNA decay: comparison of endpoint and real-time methods

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23 August 2017

Scavenger receptors and oxidized low density lipoproteins

1 reference

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23 August 2017

The expression of the lectin-like oxidized low-density lipoprotein receptor (LOX-1) on human vascular smooth muscle cells and monocytes and its down-regulation by lovastatin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783367

23 August 2017

UV irradiation activates JNK and increases alphaI(I) collagen gene expression in rat hepatic stellate cells

1 reference

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An endothelial receptor for oxidized low-density lipoprotein

1 reference

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Cloning, characterization, and expression of the transforming growth factor-beta type I receptor promoter in fetal rat bone cells

1 reference

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Isolation and characterization of the mouse PDGF beta-receptor promoter

1 reference

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Reduced uptake of oxidized low density lipoproteins in monocyte-derived macrophages from CD36-deficient subjects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783367

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Natural derivatives of curcumin attenuate the Wnt/beta-catenin pathway through down-regulation of the transcriptional coactivator p300.

1 reference

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14 September 2017

Curcumin: potential for hepatic fibrosis therapy?

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Pioglitazone inhibits LOX-1 expression in human coronary artery endothelial cells by reducing intracellular superoxide radical generation

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Peroxisome-proliferator-activated receptor gamma suppresses Wnt/beta-catenin signalling during adipogenesis.

1 reference

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A dominant-negative peroxisome proliferator-activated receptor gamma (PPARgamma) mutant is a constitutive repressor and inhibits PPARgamma-mediated adipogenesis

1 reference

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28 September 2017

Lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1) transcriptional regulation by Oct-1 in human endothelial cells: implications for atherosclerosis

1 reference

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26 June 2018

PPARgamma regulates adipocyte cholesterol metabolism via oxidized LDL receptor 1

1 reference

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26 June 2018

Activation of PPARgamma is required for curcumin to induce apoptosis and to inhibit the expression of extracellular matrix genes in hepatic stellate cells in vitro

1 reference

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1 reference

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26 June 2018

Peroxisome proliferator-activated receptors and hepatic stellate cell activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783367

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Oxidized LDL and malondialdehyde-modified LDL in patients with acute coronary syndromes and stable coronary artery disease

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Expression of platelet-derived growth factor and its receptors in normal human liver and during active hepatic fibrogenesis

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26 June 2018

Screening for liver fibrosis by using a noninvasive biomarker in patients with diabetes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783367

2 September 2018

Canonical Wnt signaling maintains the quiescent stage of hepatic stellate cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783367

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Curcumin protects the rat liver from CCl4-caused injury and fibrogenesis by attenuating oxidative stress and suppressing inflammation

1 reference

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Metabolic syndrome is associated with severe fibrosis in chronic viral hepatitis and non-alcoholic steatohepatitis

1 reference

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2 September 2018

Curcumin suppresses the expression of extracellular matrix genes in activated hepatic stellate cells by inhibiting gene expression of connective tissue growth factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783367

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Systemic levels of lipid peroxidation and its metabolic and dietary correlates in patients with nonalcoholic steatohepatitis

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2 September 2018

Mechanistic role of cytochrome P450 monooxygenases in oxidized low-density lipoprotein-induced vascular injury: therapy through LOX-1 receptor antagonism?

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2 September 2018

Activation of peroxisome proliferator-activated receptor-gamma contributes to the inhibitory effects of curcumin on rat hepatic stellate cell growth

1 reference

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Beta-catenin-mediated transactivation and cell-cell adhesion pathways are important in curcumin (diferuylmethane)-induced growth arrest and apoptosis in colon cancer cells

1 reference

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2 September 2018

Oxidized low-density lipoproteins bind to the scavenger receptor, CD36, of hepatic stellate cells and stimulate extracellular matrix synthesis

1 reference

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PPARgamma ligands inhibit TNF-alpha-induced LOX-1 expression in cultured endothelial cells.

1 reference

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2 September 2018

Elevated levels of oxidized low density lipoprotein show a positive relationship with the severity of acute coronary syndromes

1 reference

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1 reference

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Lectin-Like Oxidized Low-Density Lipoprotein Receptor-1-Mediated Autophagy in Human Granulosa Cells as an Alternative of Programmed Cell Death

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21 January 2018

Non-alcoholic steatohepatitis: another disease of affluence

1 reference

https://pubmed.ncbi.nlm.nih.gov/19736547

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The interruption of the PDGF and EGF signaling pathways by curcumin stimulates gene expression of PPARgamma in rat activated hepatic stellate cell in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/19736547

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Wnt signaling enhances the activation and survival of human hepatic stellate cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19736547

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inverse relationship between circulating oxidized low density lipoprotein (oxLDL) and anti-oxLDL antibody levels in healthy subjects

1 reference

https://pubmed.ncbi.nlm.nih.gov/19736547

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Peroxisome proliferator-activated receptor gamma transcriptional regulation is involved in platelet-derived growth factor-induced proliferation of human hepatic stellate cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19736547

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Upregulation of endothelial receptor for oxidized LDL (LOX-1) by oxidized LDL and implications in apoptosis of human coronary artery endothelial cells: evidence from use of antisense LOX-1 mRNA and chemical inhibitors

1 reference

https://pubmed.ncbi.nlm.nih.gov/19736547

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ligands of peroxisome proliferator-activated receptor γ modulate profibrogenic and proinflammatory actions in hepatic stellate cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19736547

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1038/LABINVEST.2009.93

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

ResearchGate publication ID

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