Absolute quantification of aldehyde oxidase protein in human liver using liquid chromatography-tandem mass spectrometry (Q37444937)

20 August 2017

Absolute quantification of aldehyde oxidase protein in human liver using liquid chromatography-tandem mass spectrometry (English)

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liquid chromatography-tandem mass spectrometry

20 August 2017

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John T Barr

1

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20 August 2017

Jeffrey P Jones

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2

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20 August 2017

Carolyn A Joswig-Jones

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3

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20 August 2017

Dan A Rock

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4

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20 August 2017

language of work or name

English

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publication date

19 September 2013

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20 August 2017

Molecular Pharmaceutics

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20 August 2017

10

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20 August 2017

10

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20 August 2017

3842-3849

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describes a project that uses

20 August 2017

liquid chromatography-tandem mass spectrometry

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Targeted quantitation of proteins by mass spectrometry.

inferred from title

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3883672

Predicting intrinsic clearance for drugs and drug candidates metabolized by aldehyde oxidase

23 August 2017

1 reference

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Evidence for substrate-dependent inhibition profiles for human liver aldehyde oxidase

23 August 2017

1 reference

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Aldehyde oxidase functions as a superoxide generating NADH oxidase: an important redox regulated pathway of cellular oxygen radical formation

23 August 2017

1 reference

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The impact of single nucleotide polymorphisms on human aldehyde oxidase

23 August 2017

1 reference

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Characterization of aldehyde oxidase enzyme activity in cryopreserved human hepatocytes

23 August 2017

1 reference

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Aldehyde Oxidase: An Enzyme of Emerging Importance in Drug Discovery

23 August 2017

1 reference

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In vitro-in vivo correlation for intrinsic clearance for drugs metabolized by human aldehyde oxidase

23 August 2017

1 reference

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Characterization of the magnitude and mechanism of aldehyde oxidase-mediated nitric oxide production from nitrite

23 August 2017

1 reference

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Purification and mechanism of human aldehyde oxidase expressed in Escherichia coli

23 August 2017

1 reference

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Small-interference RNA-mediated knock-down of aldehyde oxidase 1 in 3T3-L1 cells impairs adipogenesis and adiponectin release

23 August 2017

1 reference

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Aldehyde oxidase 1 is highly abundant in hepatic steatosis and is downregulated by adiponectin and fenofibric acid in hepatocytes in vitro.

23 August 2017

1 reference

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Mammalian molybdo-flavoenzymes, an expanding family of proteins: structure, genetics, regulation, function and pathophysiology

23 August 2017

1 reference

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Metabolism of retinaldehyde and other aldehydes in soluble extracts of human liver and kidney

23 August 2017

1 reference

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Analysis of aldehyde oxidase and xanthine dehydrogenase/oxidase as possible candidate genes for autosomal recessive familial amyotrophic lateral sclerosis

23 August 2017

1 reference

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Increasing recognition of the importance of aldehyde oxidase in drug development and discovery

23 August 2017

1 reference

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The enzymic oxidation of pyridoxal by liver aldehyde oxidase

23 August 2017

1 reference

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Development of a highly sensitive method using liquid chromatography-multiple reaction monitoring to quantify membrane P-glycoprotein in biological matrices and relationship to transport function

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3883672

Preparation of aldehyde oxidase in its native and deflavo forms. Comparison of spectroscopic and catalytic properties.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3883672

Simultaneous absolute protein quantification of carboxylesterases 1 and 2 in human liver tissue fractions using liquid chromatography-tandem mass spectrometry

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3883672

Simultaneous absolute protein quantification of transporters, cytochromes P450, and UDP-glucuronosyltransferases as a novel approach for the characterization of individual human liver: comparison with mRNA levels and activities.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3883672

Case report of extensive metabolism by aldehyde oxidase in humans: pharmacokinetics and metabolite profile of FK3453 in rats, dogs, and humans.

2 September 2018

1 reference

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Species-specific metabolism of SGX523 by aldehyde oxidase and the toxicological implications

2 September 2018

1 reference

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In silico and in vitro pharmacogenetics: aldehyde oxidase rapidly metabolizes a p38 kinase inhibitor

2 September 2018

1 reference

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The multi-hit process and the antagonistic roles of tumor necrosis factor-alpha and adiponectin in non alcoholic fatty liver disease.

2 September 2018

1 reference

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Role of mammalian cytosolic molybdenum Fe-S flavin hydroxylases in hepatic injury

2 September 2018

1 reference

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Efficient and specific trypsin digestion of microgram to nanogram quantities of proteins in organic-aqueous solvent systems

2 September 2018

1 reference

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Quantitation of human glutathione S-transferases in complex matrices by liquid chromatography/tandem mass spectrometry with signature peptides

2 September 2018

1 reference

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Involvement of the narJ and mob gene products in distinct steps in the biosynthesis of the molybdoenzyme nitrate reductase in Escherichia coli

2 September 2018

1 reference

12 December 2020

Analysis of human alcohol- and aldehyde-metabolizing isozymes by electrophoresis and isoelectric focusing

1 reference

12 December 2020

Purification of rabbit liver aldehyde oxidase by affinity chromatography on benzamidine sepharose 6B

1 reference

12 December 2020

Ethanol-induced iron mobilization: role of acetaldehyde-aldehyde oxidase generated superoxide

1 reference

12 December 2020

Inter-species variation in the metabolism and inhibition of N-[(2'-dimethylamino)ethyl]acridine-4-carboxamide (DACA) by aldehyde oxidase

1 reference

12 December 2020

Identifiers

DOI

10.1021/MP4003046

1 reference

20 August 2017

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20 August 2017

PubMed publication ID

24006961

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