Adult neural stem cells expressing IL-10 confer potent immunomodulation and remyelination in experimental autoimmune encephalitis (Q37452238)

20 August 2017

Adult neural stem cells expressing IL-10 confer potent immunomodulation and remyelination in experimental autoimmune encephalitis (English)

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20 August 2017

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Jingxian Yang

1

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20 August 2017

Zhilong Jiang

2

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20 August 2017

Denise C Fitzgerald

3

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20 August 2017

Cungen Ma

4

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20 August 2017

Shuo Yu

5

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20 August 2017

Hongmei Li

6

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20 August 2017

Zhao Zhao

7

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20 August 2017

Yonghai Li

8

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20 August 2017

Bogoljub Ciric

9

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20 August 2017

Mark Curtis

10

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20 August 2017

Abdolmohamad Rostami

11

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20 August 2017

Guang-Xian Zhang

12

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20 August 2017

language of work or name

English

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publication date

2 November 2009

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Journal of Clinical Investigation

20 August 2017

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20 August 2017

119

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20 August 2017

12

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20 August 2017

3678-3691

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describes a project that uses

20 August 2017

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2786785/fullTextXML

inferred from PubMed Central ID database lookup

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IL-23 is increased in dendritic cells in multiple sclerosis and down-regulation of IL-23 by antisense oligos increases dendritic cell IL-10 production

23 August 2017

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IL-10-dependent infectious tolerance after the treatment of experimental allergic encephalomyelitis with redirected CD4+CD25+ T lymphocytes

23 August 2017

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23 August 2017

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Myelin oligodendrocyte glycoprotein-specific T cell receptor transgenic mice develop spontaneous autoimmune optic neuritis.

23 August 2017

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Transplanted multipotential neural precursor cells migrate into the inflamed white matter in response to experimental autoimmune encephalomyelitis

23 August 2017

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23 August 2017

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23 August 2017

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23 August 2017

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23 August 2017

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23 August 2017

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Critical Influences of the Cytokine Orchestration on the Outcome of Myelin Antigen‐Specific T‐Cell Autoimmunity in Experimental Autoimmune Encephalomyelitis and Multiple Sclerosis

14 September 2017

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Different therapeutic outcomes in experimental allergic encephalomyelitis dependent upon the mode of delivery of IL-10: a comparison of the effects of protein, adenoviral or retroviral IL-10 delivery into the central nervous system

14 September 2017

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IL-10 is critical in the regulation of autoimmune encephalomyelitis as demonstrated by studies of IL-10- and IL-4-deficient and transgenic mice.

28 September 2017

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Neurotrophin-3 and brain-derived neurotrophic factor induce oligodendrocyte proliferation and myelination of regenerating axons in the contused adult rat spinal cord.

28 September 2017

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Maturational changes in laminin, fibronectin, collagen IV, and perlecan in germinal matrix, cortex, and white matter and effect of betamethasone

26 June 2018

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Intravenously transplanted human neural stem cells migrate to the injured spinal cord in adult mice in an SDF-1- and HGF-dependent manner.

2 September 2018

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2 September 2018

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Th17 and Th1 responses directed against the immunizing epitope, as opposed to secondary epitopes, dominate the autoimmune repertoire during relapses of experimental autoimmune encephalomyelitis

2 September 2018

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Myelination of congenitally dysmyelinated spinal cord axons by adult neural precursor cells results in formation of nodes of Ranvier and improved axonal conduction.

2 September 2018

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Long-term fate of neural precursor cells following transplantation into developing and adult CNS.

2 September 2018

1 reference

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C1q and MBL, components of the innate immune system, influence monocyte cytokine expression.

2 September 2018

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Interaction of Fas ligand and Fas expressed on osteoclast precursors increases osteoclastogenesis.

2 September 2018

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Grafts of brain-derived neurotrophic factor and neurotrophin 3-transduced primate Schwann cells lead to functional recovery of the demyelinated mouse spinal cord.

2 September 2018

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Intraventricular transplantation of neural precursor cell spheres attenuates acute experimental allergic encephalomyelitis

2 September 2018

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Quantifying the early stages of remyelination following cuprizone-induced demyelination.

2 September 2018

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Dual upregulation of Fas and Bax promotes alloreactive T cell apoptosis in IL-10 gene targeting of cardiac allografts

2 September 2018

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Injection of adult neurospheres induces recovery in a chronic model of multiple sclerosis

2 September 2018

1 reference

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A crucial role for neurotrophin-3 in oligodendrocyte development

2 September 2018

1 reference

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Upregulation of chemokine receptor expression by IL-10/IL-4 in adult neural stem cells

2 September 2018

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12 December 2020

Neural precursors attenuate autoimmune encephalomyelitis by peripheral immunosuppression

1 reference

12 December 2020

CD40 expression by microglial cells is required for their completion of a two-step activation process during central nervous system autoimmune inflammation

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12 December 2020

IL-10 induces apoptosis in human monocytes involving the CD95 receptor/ligand pathway

1 reference

12 December 2020

Opsonization with C1q and mannose-binding lectin targets apoptotic cells to dendritic cells

1 reference

12 December 2020

Suppressive effect of IL-27 on encephalitogenic Th17 cells and the effector phase of experimental autoimmune encephalomyelitis

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12 December 2020

Efficiency, efficacy and adverse effects of adenovirus versus liposome-mediated ex vivo immunosuppressive cytokine gene transfer on the functional cardiac allografts

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12 December 2020

Identifiers

DOI

10.1172/JCI37914

1 reference

20 August 2017

1 reference

20 August 2017

PubMed publication ID

19884657

1 reference