Conversion of the interleukin 1 receptor antagonist into an agonist by site-specific mutagenesis (Q37456977)

20 August 2017

Conversion of the interleukin 1 receptor antagonist into an agonist by site-specific mutagenesis (English)

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20 August 2017

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Ju G

1

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20 August 2017

Labriola-Tompkins E

2

1 reference

20 August 2017

Campen CA

3

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20 August 2017

Benjamin WR

4

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20 August 2017

Karas J

5

1 reference

20 August 2017

Plocinski J

6

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20 August 2017

Biondi D

7

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20 August 2017

Kaffka KL

8

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20 August 2017

Kilian PL

9

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20 August 2017

Eisenberg SP

10

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20 August 2017

language of work or name

English

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publication date

1 April 1991

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Proceedings of the National Academy of Sciences of the United States of America

20 August 2017

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20 August 2017

88

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20 August 2017

7

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20 August 2017

2658-2662

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Review important concepts of receptor theory

20 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=51297

Cloning and expression of murine interleukin-1 cDNA in Escherichia coli

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=51297

Both a monoclonal antibody and antisera specific for determinants unique to individual cloned helper T cell lines can substitute for antigen and antigen-presenting cells in the activation of T cells

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=51297

Nucleotide sequence of human monocyte interleukin 1 precursor cDNA

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=51297

Purification and characterization of a cytosolic 65-kilodalton phosphoprotein in human leukocytes whose phosphorylation is augmented by stimulation with interleukin 1.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=51297

Versatile expression vectors for high-level synthesis of cloned gene products in Escherichia coli

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=51297

Cloning, sequence and expression of two distinct human interleukin-1 complementary DNAs

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=51297

cDNA expression cloning of the IL-1 receptor, a member of the immunoglobulin superfamily

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=51297

The cell surface receptors for interleukin-1 alpha and interleukin-1 beta are identical

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=51297

Crystallographic refinement of interleukin 1 beta at 2.0 A resolution

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=51297

Crystal structure of recombinant human interleukin-1 beta at 2.0 A resolution

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=51297

Evidence for different interleukin 1 receptors in murine B- and T-cell lines

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=51297

Two high-affinity interleukin 1 receptors represent separate gene products

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=51297

Interleukin-1 and its receptor.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=51297

T-cell interleukin 1 receptor cDNA expressed in Chinese hamster ovary cells regulates functional responses to interleukin 1.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=51297

Biological properties of recombinant human monocyte-derived interleukin 1 receptor antagonist

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=51297

IL-1 and its receptor are translocated to the nucleus

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=51297

Primary structure and functional expression from complementary DNA of a human interleukin-1 receptor antagonist

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=51297

Interleukin-1 receptor antagonist activity of a human interleukin-1 inhibitor

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=51297

Crystal structure of the cytokine interleukin-1 beta.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=51297

A human IL-1 alpha derivative which lacks prostaglandin E2 inducing activity and inhibits the activity of IL-1 through receptor competition

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=51297

Purification and characterization of a 26-kDa competitive inhibitor of interleukin 1.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=51297

Amino acid sequence analysis of human interleukin 1 (IL-1). Evidence for biochemically distinct forms of IL-1.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=51297

Recombinant human interleukin 1 alpha: purification and biological characterization.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=51297

Interleukin 1 alpha and interleukin 1 beta bind to the same receptor on T cells.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=51297

Interleukin-1 signal transduction. Increased GTP binding and hydrolysis in membranes of a murine thymoma line (EL4).

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=51297

Effects of immune complexes on production by human monocytes of interleukin 1 or an interleukin 1 inhibitor

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=51297

IL-1 and TNF transmodulate epidermal growth factor receptors by a protein kinase C-independent mechanism

2 September 2018

1 reference

12 December 2020

Natural and recombinant human interleukin 1-beta is cytotoxic for human melanoma cells

1 reference

12 December 2020

A point mutation uncouples human interleukin-1 beta biological activity and receptor binding

1 reference

12 December 2020

Interleukin-1 costimulatory activity on the interleukin-2 promoter via AP-1

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.88.7.2658

1 reference

20 August 2017

0 references

1 reference

20 August 2017

PubMed publication ID

1826365

1 reference