Dysregulated STAT1-SOCS1 control of JAK2 promotes mammary luminal progenitor cell survival and drives ERα(+) tumorigenesis (Q37475469)

20 August 2017

Dysregulated STAT1-SOCS1 control of JAK2 promotes mammary luminal progenitor cell survival and drives ERα(+) tumorigenesis (English)

1 reference

20 August 2017

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24037089%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

James Michael White

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24037089%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

author name string

S R Chan

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24037089%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

C G Rickert

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24037089%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

K C F Sheehan

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24037089%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

C Arthur

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24037089%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

J A Allen

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24037089%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

J Archambault

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24037089%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

S Lonardi

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24037089%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

T M McDevitt

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24037089%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

D Bhattacharya

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24037089%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

M V Lorenzi

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24037089%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

D C Allred

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24037089%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

R D Schreiber

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24037089%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

publication date

13 September 2013

1 reference

Cell Death & Differentiation

20 August 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24037089%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

volume

21

1 reference

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13 June 2020

issue

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24037089%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

page(s)

234-246

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24037089%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/cdd.2013.116

13 June 2020

exact match

0 references

cites work

STAT1-deficient mice spontaneously develop estrogen receptor α-positive luminal mammary carcinomas

1 reference

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Putting the brakes on mammary tumorigenesis: loss of STAT1 predisposes to intraepithelial neoplasias

23 August 2017

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Constitutive activation of JAK2 in mammary epithelium elevates Stat5 signalling, promotes alveologenesis and resistance to cell death, and contributes to tumourigenesis

23 August 2017

1 reference

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The JAK2/STAT3 signaling pathway is required for growth of CD44⁺CD24⁻ stem cell-like breast cancer cells in human tumors

23 August 2017

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Loss of STAT1 from mouse mammary epithelium results in an increased Neu-induced tumor burden.

23 August 2017

1 reference

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Janus kinase 2 is required for the initiation but not maintenance of prolactin-induced mammary cancer

23 August 2017

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The JAK2 inhibitor AZD1480 potently blocks Stat3 signaling and oncogenesis in solid tumors

23 August 2017

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STATs in cancer inflammation and immunity: a leading role for STAT3

23 August 2017

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Development of mammary luminal progenitor cells is controlled by the transcription factor STAT5A

23 August 2017

1 reference

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The Stat family of transcription factors have diverse roles in mammary gland development

23 August 2017

1 reference

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JAK2, but not Src family kinases, is required for STAT, ERK, and Akt signaling in response to growth hormone in preadipocytes and hepatoma cells

23 August 2017

1 reference

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23 August 2017

1 reference

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From bench to bedside: future potential for the translation of prolactin inhibitors as breast cancer therapeutics

23 August 2017

1 reference

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23 August 2017

1 reference

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ABIN-3: a molecular basis for species divergence in interleukin-10-induced anti-inflammatory actions

23 August 2017

1 reference

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Socs2 and elf5 mediate prolactin-induced mammary gland development

23 August 2017

1 reference

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Generation of a functional mammary gland from a single stem cell

23 August 2017

1 reference

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Purification and unique properties of mammary epithelial stem cells

23 August 2017

1 reference

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Negative regulation of cytokine and TLR signalings by SOCS and others

23 August 2017

1 reference

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Effects of chemotherapy and hormonal therapy for early breast cancer on recurrence and 15-year survival: an overview of the randomised trials

23 August 2017

1 reference

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Inactivation of Stat5 in mouse mammary epithelium during pregnancy reveals distinct functions in cell proliferation, survival, and differentiation

23 August 2017

1 reference

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Impaired alveologenesis and maintenance of secretory mammary epithelial cells in Jak2 conditional knockout mice

23 August 2017

1 reference

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Prolactin induces ERalpha-positive and ERalpha-negative mammary cancer in transgenic mice

23 August 2017

1 reference

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Investigation of the transcriptional changes underlying functional defects in the mammary glands of prolactin receptor knockout mice

23 August 2017

1 reference

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In vitro propagation and transcriptional profiling of human mammary stem/progenitor cells

23 August 2017

1 reference

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Targeted inhibition of Stat3 with a decoy oligonucleotide abrogates head and neck cancer cell growth

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3890946

SOCS1 deficiency results in accelerated mammary gland development and rescues lactation in prolactin receptor-deficient mice

23 August 2017

1 reference

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IFN regulatory factor-1-mediated transcriptional activation of mouse STAT-induced STAT inhibitor-1 gene promoter by IFN-gamma

23 August 2017

1 reference

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Inhibition and restoration of prolactin signal transduction by suppressors of cytokine signaling

23 August 2017

1 reference

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Stat5a and Stat5b proteins have essential and nonessential, or redundant, roles in cytokine responses

23 August 2017

1 reference

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Prolactin (PRL) and its receptor: actions, signal transduction pathways and phenotypes observed in PRL receptor knockout mice

23 August 2017

1 reference

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Receptor to nucleus signaling by prolactin and interleukin 2 via activation of latent DNA-binding factors

23 August 2017

1 reference

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Prolactin activates the interferon-regulated p91 transcription factor and the Jak2 kinase by tyrosine phosphorylation

23 August 2017

1 reference

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JAK2/STAT5 inhibition circumvents resistance to PI3K/mTOR blockade: a rationale for cotargeting these pathways in metastatic breast cancer

23 August 2017

1 reference

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Reciprocal effects of STAT5 and STAT3 in breast cancer

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3890946

Differential hypermethylation of SOCS genes in ovarian and breast carcinomas.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3890946

Prolactin recruits STAT1, STAT3 and STAT5 independent of conserved receptor tyrosines TYR402, TYR479, TYR515 and TYR580.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3890946

A STAT protein domain that determines DNA sequence recognition suggests a novel DNA-binding domain

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3890946

Stat1 is a suppressor of ErbB2/Neu-mediated cellular transformation and mouse mammary gland tumor formation

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3890946

Sp2 regulates interferon-gamma-mediated socs1 gene expression

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3890946

SOCS-1, -2, -3: selective targets and functions downstream of the prolactin receptor

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3890946

Cytokine-inducible SH2 protein (CIS3) and JAK2 binding protein (JAB) abolish prolactin receptor-mediated STAT5 signaling

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3890946

JAK2 and STAT5, but not JAK1 and STAT1, are required for prolactin-induced beta-lactoglobulin transcription

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3890946

Characterization of BMS-911543, a functionally selective small-molecule inhibitor of JAK2.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3890946

Coexpression and cross-regulation of the prolactin receptor and sex steroid hormone receptors in breast cancer.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3890946

Stat5a is mandatory for adult mammary gland development and lactogenesis.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3890946

Activation of Stat5a and Stat5b by tyrosine phosphorylation is tightly linked to mammary gland differentiation.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3890946

ELDA: extreme limiting dilution analysis for comparing depleted and enriched populations in stem cell and other assays

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3890946

Deregulated estrogen receptor alpha expression in mammary epithelial cells of transgenic mice results in the development of ductal carcinoma in situ.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3890946

Stat5a is tyrosine phosphorylated and nuclear localized in a high proportion of human breast cancers

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3890946

Basal activation of transcription factor signal transducer and activator of transcription (Stat5) in nonpregnant mouse and human breast epithelium

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3890946

Constitutive activation of Stat3 by the Src and JAK tyrosine kinases participates in growth regulation of human breast carcinoma cells

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3890946

Generation and characterization of hamster monoclonal antibodies that neutralize murine tumor necrosis factors.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3890946

Distinct stem cells contribute to mammary gland development and maintenance

2 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FCDD.2013.116

Deregulation of Stat5 expression and activation causes mammary tumors in transgenic mice

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24037089

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Increased expression of prolactin receptor gene assessed by quantitative polymerase chain reaction in human breast tumors versus normal breast tissues

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24037089

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/CDD.2013.116

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24037089%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24037089%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24037089%20AND%20SRC:MED&resulttype=core&format=json