Genetic variants influencing circulating lipid levels and risk of coronary artery disease (Q37477713)

20 August 2017

Genetic variants influencing circulating lipid levels and risk of coronary artery disease (English)

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Marjo-Riitta Järvelin

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Cornelia M. van Duijn

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Cornelia M van Duijn

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David Schlessinger

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David Schlessinger

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Samuli Ripatti

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Samuli Ripatti

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Serena Sanna

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Serena Sanna

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Aimo Ruokonen

50

Aimo Ruokonen

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Inês Barroso

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Inês Barroso

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Eleanor Wheeler

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Eleanor Wheeler

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Ida Surakka

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Ida Surakka

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20 August 2017

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Gérard Waeber

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20 August 2017

Alexandre Stewart

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Muredach P. Reilly

Muredach P Reilly

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Alistair Scott Hall

Alistair S Hall

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Karen L Mohlke

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Karen L Mohlke

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Veikko Salomaa

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Paul Elliott

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Kay-Tee Khaw

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Kay-Tee Khaw

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Nilesh J Samani

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Nicholas J Wareham

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Michael Boehnke

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Anne Jackson

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Ruth J F Loos

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Wellcome Trust Case Control Consortium

20 August 2017

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Wellcome Trust Case Control Consortium

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20 August 2017

Leena Peltonen-Palotie

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Leena Peltonen

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Peter Vollenweider

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Wendy McArdle

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David P Strachan

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Jacqueline C M Witteman

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Jacqueline C M Witteman

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Jaspal S Kooner

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Dawn M Waterworth

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Michael Inouye

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Daniel J Rader

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Y Antero Kesäniemi

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Sally L Ricketts

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John R Thompson

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Manjinder S Sandhu

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Philip Barter

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Kijoung Song

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Ruth McPherson

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S Matthijs Boekholdt

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Maksim Struchalin

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Vincent Mooser

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Jaako Tuomilehto

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Peter S Braund

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Noha Lim

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Sofie Ashford

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Hakon H Hakonarson

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20 August 2017

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Scott M Grundy

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20 August 2017

Li Chen

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20 August 2017

Jing Hua Zhao

5

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20 August 2017

Weihua Zhang

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20 August 2017

Xin Yuan

9

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20 August 2017

Jian'an Luan

11

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20 August 2017

Elizabeth H Young

14

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20 August 2017

David Hadley

15

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20 August 2017

Sheila A Rodwell

23

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20 August 2017

Angelo Scuteri

31

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20 August 2017

Robert Roberts

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20 August 2017

Robert W Mahley

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Lon Cardon

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John C Chambers

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20 August 2017

Stephen E Epstein

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20 August 2017

language of work or name

English

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publication date

23 September 2010

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Arteriosclerosis, Thrombosis, and Vascular Biology

20 August 2017

13

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published in

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20 August 2017

30

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11

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20 August 2017

2264-2276

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Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis

20 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3891568

Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3891568

LXR regulates cholesterol uptake through Idol-dependent ubiquitination of the LDL receptor

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3891568

Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3891568

Novel LPL mutations associated with lipoprotein lipase deficiency: two case reports and a literature review

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3891568

Apolipoprotein B levels, APOB alleles, and risk of ischemic cardiovascular disease in the general population, a review

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3891568

Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3891568

Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3891568

Genome-wide association analysis of metabolic traits in a birth cohort from a founder population

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3891568

Common variants at 30 loci contribute to polygenic dyslipidemia

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3891568

Seven lipoprotein lipase gene polymorphisms, lipid fractions, and coronary disease: a HuGE association review and meta-analysis

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3891568

Strengthening causal inference in cardiovascular epidemiology through Mendelian randomization

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3891568

Association of cholesteryl ester transfer protein genotypes with CETP mass and activity, lipid levels, and coronary risk

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3891568

Genome-wide association studies for complex traits: consensus, uncertainty and challenges

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3891568

Laboratory assessment of HDL heterogeneity and function

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3891568

Relative atherogenicity and predictive value of non-high-density lipoprotein cholesterol for coronary heart disease

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3891568

LDL-cholesterol concentrations: a genome-wide association study

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3891568

Promise of low-density lipoprotein-lowering therapy for primary and secondary prevention

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3891568

Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3891568

Newly identified loci that influence lipid concentrations and risk of coronary artery disease

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3891568

Genome-wide association study identifies genes for biomarkers of cardiovascular disease: serum urate and dyslipidemia

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3891568

New insights into the role of HDL as an anti-inflammatory agent in the prevention of cardiovascular disease

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3891568

Genetics of cardiovascular diseases: from single mutations to the whole genome

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3891568

PLINK: a tool set for whole-genome association and population-based linkage analyses

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3891568

High-density lipoprotein as a therapeutic target: a systematic review

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3891568

Genomewide association analysis of coronary artery disease

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3891568

Mechanisms of disease: lessons from ethnicity in the role of triglyceride metabolism in ischemic heart disease

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3891568

A new multipoint method for genome-wide association studies by imputation of genotypes

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3891568

Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3891568

GenABEL: an R library for genome-wide association analysis

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3891568

Mechanisms of disease: genetic causes of familial hypercholesterolemia

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3891568

Common genetic variants of the FADS1 FADS2 gene cluster and their reconstructed haplotypes are associated with the fatty acid composition in phospholipids

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3891568

Sequence variations in PCSK9, low LDL, and protection against coronary heart disease

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3891568

The MLL fusion gene, MLL-AF4, regulates cyclin-dependent kinase inhibitor CDKN1B (p27kip1) expression

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3891568

The APOA1/C3/A4/A5 gene cluster, lipid metabolism and cardiovascular disease risk.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3891568

Factors of risk in the development of coronary heart disease--six year follow-up experience. The Framingham Study

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3891568

Human skeletal muscle expresses a glycogen-targeting subunit of PP1 that is identical to the insulin-sensitive glycogen-targeting subunit G(L) of liver

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3891568

Genomic control for association studies

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3891568

HDL metabolism and CETP inhibition

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3891568

Apolipoprotein A-V, triglycerides and risk of coronary artery disease: the prospective Epic-Norfolk Population Study

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3891568

Kinesin family member 6 variant Trp719Arg does not associate with angiographically defined coronary artery disease in the Ottawa Heart Genomics Study

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3891568

The human zinc transporter SLC39A8 (Zip8) is critical in zinc-mediated cytoprotection in lung epithelia

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3891568

Genome-wide scan identifies variation in MLXIPL associated with plasma triglycerides

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3891568

Triglycerides and coronary heart disease revisited (again).

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3891568

Enhanced apoB48 metabolism in lipoprotein lipase X447 homozygotes.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3891568

Relation between atherogenic dyslipidemia and the Adult Treatment Program-III definition of metabolic syndrome (Genetic Epidemiology of Metabolic Syndrome Project).

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3891568

EPIC-Norfolk: study design and characteristics of the cohort. European Prospective Investigation of Cancer

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3891568

Genetic and phenotypic architecture of metabolic syndrome-associated components in dyslipidemic and normolipidemic subjects: The GEMS Study

2 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3891568

Nonfasting Triglycerides and Risk of Myocardial Infarction, Ischemic Heart Disease, and Death in Men and Women

3 December 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20864672

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1161/ATVBAHA.109.201020

1 reference

20 August 2017

1 reference

20 August 2017

PubMed publication ID

20864672

1 reference