Interactions between human cytochrome P450 enzymes and steroids: physiological and pharmacological implications. (Q37497393)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19473111%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

review article

1 reference

title

Interactions between human cytochrome P450 enzymes and steroids: physiological and pharmacological implications (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19473111%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19473111%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

author name string

Ling Yang

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19473111%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

language of work or name

English

0 references

publication date

1 June 2009

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19473111%20AND%20SRC:MED&resulttype=core&format=json

Expert Opinion on Drug Metabolism & Toxicology

29 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19473111%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

volume

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19473111%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

issue

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19473111%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

page(s)

621-629

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19473111%20AND%20SRC:MED&resulttype=core&format=json

Steroid analysis for medical diagnosis

29 January 2020

cites work

1 reference

https://api.crossref.org/works/10.1517%2F17425250902967648

Contraceptive applications of progesterone receptor modulators

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250902967648

A review of the chemistry, biological action, and clinical applications of anabolic-androgenic steroids

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250902967648

Chromatographic procedures for the isolation of plant steroids

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250902967648

Dehydroepiandrosterone (DHEA) metabolism in Saccharomyces cerevisiae expressing mammalian steroid hydroxylase CYP7B: Ayr1p and Fox2p display 17beta-hydroxysteroid dehydrogenase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250902967648

Cytochrome P450s and other enzymes in drug metabolism and toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250902967648

Sulfonation and molecular action

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250902967648

Genotoxic metabolites of estradiol in breast: potential mechanism of estradiol induced carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250902967648

Steroid hormone biotransformation and xenobiotic induction of hepatic steroid metabolizing enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250902967648

Clinical importance of the cytochromes P450

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250902967648

Cytochrome P450-mediated metabolism of estrogens and its regulation in human.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250902967648

Functional evolution of the pregnane X receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250902967648

CYP induction-mediated drug interactions: in vitro assessment and clinical implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250902967648

Cytochrome P450 and gene activation--from pharmacology to cholesterol elimination and regression of atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250902967648

Tissue distribution of mRNA expression of human cytochrome P450 isoforms assessed by high-sensitivity real-time reverse transcription PCR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250902967648

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250902967648

Characterization of the oxidative metabolites of 17beta-estradiol and estrone formed by 15 selectively expressed human cytochrome p450 isoforms

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250902967648

Contribution of human hepatic cytochrome P450 isoforms to regioselective hydroxylation of steroid hormones

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250902967648

Pregnenolone-7 beta-hydroxylating activities of yeast-expressed mouse cytochrome P450-1A1 and mouse-tissue microsomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250902967648

Interactions of hepatic cytochromes P-450 with steroid hormones. Regioselectivity and stereospecificity of steroid metabolism and hormonal regulation of rat P-450 enzyme expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250902967648

Roles of cytochromes P450 1A2 and 3A4 in the oxidation of estradiol and estrone in human liver microsomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250902967648

Progesterone and testosterone hydroxylation by cytochromes P450 2C19, 2C9, and 3A4 in human liver microsomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250902967648

Identification of the human cytochrome P450 enzymes involved in the in vitro biotransformation of lynestrenol and norethindrone

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250902967648

Cytochrome P450-mediated oxidation of glucuronide derivatives: example of estradiol-17beta-glucuronide oxidation to 2-hydroxy-estradiol-17beta-glucuronide by CYP 2C8.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250902967648

Characterization of testosterone 11 beta-hydroxylation catalyzed by human liver microsomal cytochromes P450.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250902967648

Differential catalytic properties in metabolism of endogenous and exogenous substrates among CYP3A enzymes expressed in COS-7 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250902967648

Metabolic profiling and cytochrome P450 reaction phenotyping of medroxyprogesterone acetate

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250902967648

Testosterone and dihydrotestosterone tissue levels in recurrent prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250902967648

Targeting CYP17: established and novel approaches in prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250902967648

Overview of steroidogenic enzymes in the pathway from cholesterol to active steroid hormones

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250902967648

Aromatase inhibitors in the treatment of breast cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250902967648

Aromatase in the brain: not just for reproduction anymore.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250902967648

Extraadrenal 21-hydroxylation by CYP2C19 and CYP3A4: effect on 21-hydroxylase deficiency.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250902967648

Inhibitory effect of medroxyprogesterone acetate on human liver cytochrome P450 enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250902967648

Medroxyprogesterone abrogates the inhibitory effects of estradiol on vascular smooth muscle cells by preventing estradiol metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250902967648

Gastrointestinal and systemic uptake of bismuth in mice after oral exposure

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250902967648

Interactions of herbs with cytochrome P450.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250902967648

In vitro effect of standardized ginseng extracts and individual ginsenosides on the catalytic activity of human CYP1A1, CYP1A2, and CYP1B1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250902967648

Effects of ginseng components on c-DNA-expressed cytochrome P450 enzyme catalytic activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250902967648

The inhibitory effect of intestinal bacterial metabolite of ginsenosides on CYP3A activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250902967648

Influence of ginsenoside Rh1 and F1 on human cytochrome p450 enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250902967648

In vitro approaches to investigate mechanism-based inactivation of CYP enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250902967648

Mechanism-based inactivation of cytochrome P450 3A4 by 17 alpha-ethynylestradiol: evidence for heme destruction and covalent binding to protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250902967648

Metabolic activation of mifepristone [RU486; 17beta-hydroxy-11beta-(4-dimethylaminophenyl)-17alpha-(1-propynyl)-estra-4,9-dien-3-one] by mammalian cytochromes P450 and the mechanism-based inactivation of human CYP2B6.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250902967648

Heterotropic cooperativity of cytochrome P450 3A4 and potential drug-drug interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250902967648

Effects of endogenous steroids on CYP3A4-mediated drug metabolism by human liver microsomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250902967648

CYP3A4 and CYP3A7-mediated carbamazepine 10,11-epoxidation are activated by differential endogenous steroids

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250902967648

Direct interaction between substrates and endogenous steroids in the active site may change the activity of cytochrome P450 3A4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250902967648

Involvement of steroids and cytochromes P(450) species in the triggering of immune defenses

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250902967648

The human cytochrome P4507B1: catalytic activity studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250902967648

10.1517/17425250902967648

21 January 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19473111%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

1 reference