Lessons learned from studying families genetically predisposed to type 2 diabetes mellitus (Q37505520)

20 August 2017

1 reference

title

Lessons learned from studying families genetically predisposed to type 2 diabetes mellitus (English)

1 reference

20 August 2017

0 references

1 reference

Kenneth Cusi

1

1 reference

PubMed ID

19490821

20 August 2017

language of work or name

1 reference

1 June 2009

1 reference

20 August 2017

Current diabetes report

1 reference

20 August 2017

9

1 reference

20 August 2017

3

1 reference

20 August 2017

200-207

1 reference

https://scigraph.springernature.com/pub.10.1007/s11892-009-0033-6

20 August 2017

0 references

cites work

Slow glucose removal rate and hyperinsulinemia precede the development of type II diabetes in the offspring of diabetic parents.

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS11892-009-0033-6

Nonalcoholic fatty liver disease in type 2 diabetes mellitus

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS11892-009-0033-6

Postreceptor insulin resistance contributes to human dyslipidemia and hepatic steatosis

21 January 2018

1 reference

12 December 2020

Twins in metabolic and diabetes research: what do they tell us?

1 reference

12 December 2020

Fatty acid signaling in the beta-cell and insulin secretion

1 reference

12 December 2020

Elevated toll-like receptor 4 expression and signaling in muscle from insulin-resistant subjects

1 reference

12 December 2020

Role of fatty acids in the pathogenesis of insulin resistance and NIDDM.

1 reference

12 December 2020

Adiponectin receptors gene expression and insulin sensitivity in non-diabetic Mexican Americans with or without a family history of Type 2 diabetes

1 reference

12 December 2020

Lipid Infusion Decreases the Expression of Nuclear Encoded Mitochondrial Genes and Increases the Expression of Extracellular Matrix Genes in Human Skeletal Muscle

1 reference

12 December 2020

Molecular mechanisms of insulin resistance in humans and their potential links with mitochondrial dysfunction

1 reference

12 December 2020

(How) can we prevent type 2 diabetes?

1 reference

12 December 2020

Discordant effects of a chronic physiological increase in plasma FFA on insulin signaling in healthy subjects with or without a family history of type 2 diabetes

1 reference

12 December 2020

Prolonged elevation of plasma free fatty acids impairs pancreatic beta-cell function in obese nondiabetic humans but not in individuals with type 2 diabetes

1 reference

12 December 2020

Opposite effects of short- and long-term fatty acid infusion on insulin secretion in healthy subjects.

1 reference

12 December 2020

Skeletal muscle insulin resistance in normoglycemic subjects with a strong family history of type 2 diabetes is associated with decreased insulin-stimulated insulin receptor substrate-1 tyrosine phosphorylation

1 reference

12 December 2020

Intramyocellular lipids: anthropometric determinants and relationships with maximal aerobic capacity and insulin sensitivity

1 reference

12 December 2020

Intramyocellular lipid is associated with resistance to in vivo insulin actions on glucose uptake, antilipolysis, and early insulin signaling pathways in human skeletal muscle

1 reference

12 December 2020

Lipotoxicity of beta-cells in obesity and in other causes of fatty acid spillover

1 reference

12 December 2020

Dissociation between fat-induced in vivo insulin resistance and proximal insulin signaling in skeletal muscle in men at risk for type 2 diabetes

1 reference

12 December 2020

Ectopic lipids and organ function

1 reference

12 December 2020

Beta-cell dysfunction and glucose intolerance: results from the San Antonio metabolism (SAM) study

1 reference

12 December 2020

Islet beta cell failure in the 60% pancreatectomised obese hyperlipidaemic Zucker fatty rat: severe dysfunction with altered glycerolipid metabolism without steatosis or a falling beta cell mass

1 reference

12 December 2020

Impaired mitochondrial activity in the insulin-resistant offspring of patients with type 2 diabetes

1 reference

12 December 2020

Impaired mitochondrial substrate oxidation in muscle of insulin-resistant offspring of type 2 diabetic patients

1 reference

12 December 2020

Chronic low-dose lipid infusion in healthy patients induces markers of endothelial activation independent of its metabolic effects

1 reference

12 December 2020

Effects of fat on glucose uptake and utilization in patients with non-insulin-dependent diabetes

1 reference

12 December 2020

Beta cells in type 2 diabetes - a crucial contribution to pathogenesis

1 reference

12 December 2020

Overweight and obesity: prevalence, consequences, and causes of a growing public health problem

1 reference

12 December 2020

A sustained increase in plasma free fatty acids impairs insulin secretion in nondiabetic subjects genetically predisposed to develop type 2 diabetes

1 reference

12 December 2020

Impaired plasma nonesterified fatty acid tolerance is an early defect in the natural history of type 2 diabetes

1 reference

12 December 2020

The metabolic profile of NIDDM is fully established in glucose-tolerant offspring of two Mexican-American NIDDM parents

1 reference

12 December 2020

Elevation of plasma fatty acids by ten-hour intralipid infusion has no effect on basal or glucose-stimulated insulin secretion in normal man

1 reference

12 December 2020

Insulin secretion after short- and long-term low-grade free fatty acid infusion in men with increased risk of developing type 2 diabetes

1 reference

12 December 2020

Acute enhancement of insulin secretion by FFA in humans is lost with prolonged FFA elevation.

1 reference

12 December 2020

Acute elevation of NEFA causes hyperinsulinemia without effect on insulin secretion rate in healthy human subjects.

1 reference

12 December 2020

Effects on insulin secretion and insulin action of a 48-h reduction of plasma free fatty acids with acipimox in nondiabetic subjects genetically predisposed to type 2 diabetes.

1 reference

12 December 2020

Lipid infusion lowers sympathetic nervous activity and leads to increased beta-cell responsiveness to glucose

1 reference

12 December 2020

Insulin resistance differentially affects the PI 3-kinase- and MAP kinase-mediated signaling in human muscle

1 reference

12 December 2020

Dose-response effect of elevated plasma free fatty acid on insulin signaling

1 reference

12 December 2020

Beta cell compensation for insulin resistance in Zucker fatty rats: increased lipolysis and fatty acid signalling.

1 reference

12 December 2020

Insulin-resistant muscle is exercise resistant: evidence for reduced response of nuclear-encoded mitochondrial genes to exercise

1 reference

12 December 2020

Coordinated reduction of genes of oxidative metabolism in humans with insulin resistance and diabetes: Potential role of PGC1 and NRF1

1 reference

12 December 2020

Fuel selection in human skeletal muscle in insulin resistance: a reexamination

1 reference

12 December 2020

10.1007/S11892-009-0033-6

Identifiers

DOI

1 reference

20 August 2017

1 reference

PubMed ID

19490821