Recent cancer drug development with xanthone structures (Q37511034)

20 August 2017

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title

Recent cancer drug development with xanthone structures (English)

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20 August 2017

Younghwa Na

1

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20 August 2017

publication date

1 June 2009

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Journal of Pharmacy and Pharmacology

20 August 2017

published in

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20 August 2017

volume

61

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20 August 2017

issue

6

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20 August 2017

page(s)

707-712

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Synthesis of xanthones: an overview

20 August 2017

cites work

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Xanthones as antimalarial agents: discovery, mode of action, and optimization

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Tetraoxygenated naturally occurring xanthones

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Xanthone derivatives: new insights in biological activities.

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Potential cancer chemopreventive in vitro activities of monomeric xanthone derivatives from the marine algicolous fungus Monodictys putredinis

21 January 2018

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Induction of apoptosis by xanthones from mangosteen in human leukemia cell lines

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Characterized mechanism of alpha-mangostin-induced cell death: caspase-independent apoptosis with release of endonuclease-G from mitochondria and increased miR-143 expression in human colorectal cancer DLD-1 cells

21 January 2018

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Preferential target is mitochondria in alpha-mangostin-induced apoptosis in human leukemia HL60 cells

21 January 2018

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Psorospermin, a new antileukemic xanthone from Psorospermum febrifugum.

21 January 2018

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Cytotoxic caged-polyprenylated xanthonoids and a xanthone from Garcinia cantleyana

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Discovery, characterization and SAR of gambogic acid as a potent apoptosis inducer by a HTS assay

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Gambogic acid inhibits angiogenesis through suppressing vascular endothelial growth factor-induced tyrosine phosphorylation of KDR/Flk-1.

21 January 2018

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Gambogic acid, a potent inhibitor of survivin, reverses docetaxel resistance in gastric cancer cells

21 January 2018

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Gambogic acid inhibits the catalytic activity of human topoisomerase IIalpha by binding to its ATPase domain.

21 January 2018

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Synthesis of caged 2,3,3a,7a-tetrahydro-3,6-methanobenzofuran-7(6H)-ones: Evaluating the minimum structure for apoptosis induction by gambogic acid

21 January 2018

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A new dihydroxanthenone from a plant-associated strain of the fungus Chaetomium globosum demonstrates anticancer activity

21 January 2018

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Synthesis, and cytotoxic and antiplatelet activities of oxime- and methyloxime-containing flavone, isoflavone, and xanthone derivatives.

21 January 2018

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Synthesis and pharmacological activities of xanthone derivatives as alpha-glucosidase inhibitors

21 January 2018

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Inhibition of protein kinase C by synthetic xanthone derivatives.

21 January 2018

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A new class of nonsteroidal aromatase inhibitors: design and synthesis of chromone and xanthone derivatives and inhibition of the P450 enzymes aromatase and 17 alpha-hydroxylase/C17,20-lyase

21 January 2018

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Conformationally restricted analogues of psorospermin: design, synthesis, and bioactivity of natural-product-related bisfuranoxanthones

21 January 2018

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The chemotherapeutic agent DMXAA potently and specifically activates the TBK1-IRF-3 signaling axis

21 January 2018

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Xanthone derivatives as potential anti-cancer drugs

21 January 2018

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Synthesis of new xanthone analogues and their biological activity test--cytotoxicity, topoisomerase II inhibition, and DNA cross-linking study

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1211/JPP.61.06.0002

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20 August 2017

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