IGFBP3 promotes esophageal cancer growth by suppressing oxidative stress in hypoxic tumor microenvironment (Q37516299)

20 August 2017

IGFBP3 promotes esophageal cancer growth by suppressing oxidative stress in hypoxic tumor microenvironment (English)

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20 August 2017

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1 June 2020

author name string

Hideaki Kinugasa

2

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1 June 2020

Shingo Kagawa

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1 June 2020

Kelly A Whelan

4

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1 June 2020

Seiji Naganuma

5

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1 June 2020

Harry Subramanian

6

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1 June 2020

Sanders Chang

7

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Kei J Nakagawa

8

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1 June 2020

Naryan L Rustgi

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1 June 2020

Yoshiaki Kita

10

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1 June 2020

Shoji Natsugoe

11

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1 June 2020

Devraj Basu

12

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Phyllis A Gimotty

13

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1 June 2020

Andres J Klein-Szanto

14

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J Alan Diehl

15

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Hiroshi Nakagawa

16

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1 June 2020

publication date

15 January 2014

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American Journal of Cancer Research

20 August 2017

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1 June 2020

volume

4

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1 June 2020

issue

1

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1 June 2020

page(s)

29-41

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Hypoxia regulates CD44 and its variant isoforms through HIF-1α in triple negative breast cancer

1 June 2020

cites work

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The biological kinship of hypoxia with CSC and EMT and their relationship with deregulated expression of miRNAs and tumor aggressiveness.

23 August 2017

1 reference

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Hypoxia induces IGFBP3 in esophageal squamous cancer cells through HIF-1α-mediated mRNA transcription and continuous protein synthesis

23 August 2017

1 reference

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Tumor initiating cells in esophageal squamous cell carcinomas express high levels of CD44

23 August 2017

1 reference

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Normal and neoplastic nonstem cells can spontaneously convert to a stem-like state

23 August 2017

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CD44 variant regulates redox status in cancer cells by stabilizing the xCT subunit of system xc(-) and thereby promotes tumor growth

23 August 2017

1 reference

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Insulin-like growth factor-binding protein-3 promotes transforming growth factor-{beta}1-mediated epithelial-to-mesenchymal transition and motility in transformed human esophageal cells

23 August 2017

1 reference

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Hyaluronan stabilizes focal adhesions, filopodia, and the proliferative phenotype in esophageal squamous carcinoma cells.

23 August 2017

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Hypoxia inducible factors in cancer stem cells

23 August 2017

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Hypoxia activates the cyclooxygenase-2-prostaglandin E synthase axis

23 August 2017

1 reference

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Hypoxia-induced alveolar epithelial-mesenchymal transition requires mitochondrial ROS and hypoxia-inducible factor 1.

23 August 2017

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Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach?

23 August 2017

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Unraveling insulin-like growth factor binding protein-3 actions in human disease

23 August 2017

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Hyaluronan, CD44 and Emmprin: partners in cancer cell chemoresistance

23 August 2017

1 reference

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The epithelial-mesenchymal transition generates cells with properties of stem cells

23 August 2017

1 reference

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IGFBP3 suppresses retinopathy through suppression of oxygen-induced vessel loss and promotion of vascular regrowth.

23 August 2017

1 reference

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IGF binding protein-3 regulates hematopoietic stem cell and endothelial precursor cell function during vascular development

23 August 2017

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IGFBP-3 regulates esophageal tumor growth through IGF-dependent and independent mechanisms.

23 August 2017

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Identification of a subpopulation of cells with cancer stem cell properties in head and neck squamous cell carcinoma

23 August 2017

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EGF-mediated regulation of IGFBP-3 determines esophageal epithelial cellular response to IGF-I

23 August 2017

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The role of insulin and IGF-1 signaling in longevity

23 August 2017

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Epidermal growth factor receptor regulates aberrant expression of insulin-like growth factor-binding protein 3

23 August 2017

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Tumor cell senescence in cancer treatment

23 August 2017

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Prospective identification of tumorigenic breast cancer cells

23 August 2017

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Insulin-like growth factor (IGF)-binding protein-3 (IGFBP-3) binds to fibronectin (FN): demonstration of IGF-I/IGFBP-3/fn ternary complexes in human plasma

23 August 2017

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23 August 2017

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Redox regulation in stem-like cancer cells by CD44 variant isoforms.

2 September 2018

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A NOTCH3-mediated squamous cell differentiation program limits expansion of EMT-competent cells that express the ZEB transcription factors.

6 September 2017

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CD44: can a cancer-initiating cell profit from an abundantly expressed molecule?

6 September 2017

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Screening of senescence-associated genes with specific DNA array reveals the role of IGFBP-3 in premature senescence of human diploid fibroblasts

6 September 2017

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Tumorigenic conversion of primary human esophageal epithelial cells using oncogene combinations in the absence of exogenous Ras.

6 September 2017

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Insulin-like growth factor binding protein-3 expression is associated with growth stimulation of T47D human breast cancer cells: the role of altered epidermal growth factor signaling.

14 September 2017

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Sox2 cooperates with inflammation-mediated Stat3 activation in the malignant transformation of foregut basal progenitor cells

14 September 2017

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Epidermal growth factor receptor and mutant p53 expand an esophageal cellular subpopulation capable of epithelial-to-mesenchymal transition through ZEB transcription factors

28 September 2017

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Transforming growth factor-beta-induced cell growth inhibition in human breast cancer cells is mediated through insulin-like growth factor-binding protein-3 action.

28 September 2017

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xCT inhibition depletes CD44v-expressing tumor cells that are resistant to EGFR-targeted therapy in head and neck squamous cell carcinoma.

25 June 2018

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Insulin-like growth factor binding protein-3, in association with IGF-1 receptor, can predict prognosis in squamous cell carcinoma of the head and neck.

2 September 2018

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Signaling through the Smad pathway by insulin-like growth factor-binding protein-3 in breast cancer cells. Relationship to transforming growth factor-beta 1 signaling.

2 September 2018

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Expression of the Insulin Like Growth Factor-Binding Protein 3 (IGFBP-3) Gene is Increased in Human Renal Carcinomas

2 September 2018

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12 December 2020

Insulin-like growth factor binding protein-3 and insulin receptor substrate-1 in breast cancer: correlation with clinical parameters and disease-free survival

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12 December 2020

Correlation of Insulin-Like Growth Factor-Binding Protein-3 Messenger RNA With Protein Expression in Primary Breast Cancer Tissues: Detection of Higher Levels in Tumors With Poor Prognostic Features

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12 December 2020

Relationship between the expression of adhesion molecules in primary esophageal squamous cell carcinoma and metastatic lymph nodes

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12 December 2020

The prognostic role of loss of insulin-like growth factor-binding protein-3 expression in head and neck carcinogenesis

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12 December 2020

Low expression of IGFBP-3 predicts poor prognosis in patients with esophageal squamous cell carcinoma

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12 December 2020

Clinical significance of insulin-like growth factor-binding protein-3 expression in stage I non-small cell lung cancer

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12 December 2020

Transforming growth factor-beta stimulates production of insulin-like growth factor-binding protein-3 by human skin fibroblasts

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12 December 2020

Accumulation of insulin-like growth factor binding protein-3 in conditioned medium of human fibroblasts increases with chronologic age of donor and senescence in vitro

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12 December 2020

Targeting Bcl-xL in esophageal squamous cancer to sensitize to chemotherapy plus TRAIL-induced apoptosis while normal epithelial cells are protected by blockade of caspase 9

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12 December 2020

Identifiers

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24482736%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

PubMed publication ID

24482736

1 reference