The high affinity peroxisome proliferator-activated receptor-gamma agonist RS5444 inhibits both initiation and progression of colon tumors in azoxymethane-treated mice (Q37516766)

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scientific article published on September 2008

Language	Label	Description	Also known as
English	The high affinity peroxisome proliferator-activated receptor-gamma agonist RS5444 inhibits both initiation and progression of colon tumors in azoxymethane-treated mice	scientific article published on September 2008

Statements

scholarly article

1 reference

Europe PubMed Central

20 August 2017

The high affinity peroxisome proliferator-activated receptor-gamma agonist RS5444 inhibits both initiation and progression of colon tumors in azoxymethane-treated mice (English)

1 reference

Europe PubMed Central

20 August 2017

author name string

Weidong Su

1

1 reference

Europe PubMed Central

20 August 2017

Brian M Necela

2

1 reference

Europe PubMed Central

20 August 2017

Kosaku Fujiwara

3

1 reference

Europe PubMed Central

20 August 2017

Shinichi Kurakata

4

1 reference

Europe PubMed Central

20 August 2017

Nicole R Murray

5

1 reference

Europe PubMed Central

20 August 2017

Alan P Fields

6

1 reference

Europe PubMed Central

20 August 2017

E Aubrey Thompson

7

1 reference

Europe PubMed Central

20 August 2017

language of work or name

0 references

publication date

1 September 2008

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Europe PubMed Central

20 August 2017

number of pages

7

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inferred from page(s)

International Journal of Cancer

1 reference

Europe PubMed Central

20 August 2017

123

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Europe PubMed Central

20 August 2017

991-997

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Europe PubMed Central

20 August 2017

5

1 reference

Europe PubMed Central

20 August 2017

Effect of Rosiglitazone on the Risk of Myocardial Infarction and Death from Cardiovascular Causes

1 reference

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Protein kinase Ciota is required for Ras transformation and colon carcinogenesis in vivo

1 reference

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Peroxisome proliferator-activated receptor gamma ligands suppress colon carcinogenesis induced by azoxymethane in mice

1 reference

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Inhibition of cellular proliferation through IkappaB kinase-independent and peroxisome proliferator-activated receptor gamma-dependent repression of cyclin D1.

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Troglitazone and related compounds: therapeutic potential beyond diabetes

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Overexpression of protein kinase C betaII induces colonic hyperproliferation and increased sensitivity to colon carcinogenesis

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Aberrant crypt foci of the colon as precursors of adenoma and cancer

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An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor gamma (PPAR gamma)

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Functional genomic analysis reveals cross-talk between peroxisome proliferator-activated receptor gamma and calcium signaling in human colorectal cancer cells

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Troglitazone, a peroxisome proliferator-activated receptor gamma (PPAR gamma ) ligand, selectively induces the early growth response-1 gene independently of PPAR gamma. A novel mechanism for its anti-tumorigenic activity.

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Down syndrome candidate region 1 increases the stability of the IkappaBalpha protein: implications for its anti-inflammatory effects

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Peroxisome proliferator-activated receptor gamma promotes epithelial to mesenchymal transformation by Rho GTPase-dependent activation of ERK1/2.

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Novel high-affinity PPARgamma agonist alone and in combination with paclitaxel inhibits human anaplastic thyroid carcinoma tumor growth via p21WAF1/CIP1.

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Induction of differentiation and peroxisome proliferator-activated receptor gamma expression in colon cancer cell lines by troglitazone.

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Apoptosis induced by activation of peroxisome-proliferator activated receptor-gamma is associated with Bcl-2 and NF-kappaB in human colon cancer

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Sequential analyses of the growth and morphological characteristics of aberrant crypt foci: putative preneoplastic lesions

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Peroxisome proliferator-activated receptor gamma-mediated differentiation: a mutation in colon cancer cells reveals divergent and cell type-specific mechanisms

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Peroxisome proliferator-activated receptor gamma induces growth arrest and differentiation markers of human colon cancer cells.

1 reference

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Activators of the nuclear receptor PPARgamma enhance colon polyp formation

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Dose response and proliferative characteristics of aberrant crypt foci: putative preneoplastic lesions in rat colon.

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Identification and quantification of aberrant crypt foci and microadenomas in the human colon.

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Differential expression, distribution, and function of PPAR-gamma in the proximal and distal colon.

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Peroxisome proliferator-activated receptor gamma agonist troglitazone induces colon tumors in normal C57BL/6J mice and enhances colonic carcinogenesis in Apc1638 N/+ Mlh1+/- double mutant mice

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Peroxisome proliferator-activated receptor expression and activation in normal human colonic epithelial cells and tubular adenomas

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Concomitant suppression of hyperlipidemia and intestinal polyp formation in Apc-deficient mice by peroxisome proliferator-activated receptor ligands.

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Thiazolidinediones, a class of anti-diabetic drugs, inhibit Id2 expression through a PPARgamma-independent pathway in human aortic smooth muscle cells

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Peroxisome proliferator-activated receptor gamma is induced during differentiation of colon epithelium cells.

1 reference

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Natural history of aberrant crypt foci. A surgical approach.

1 reference

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Activation of the peroxisome proliferator-activated receptor γ promotes the development of colon tumors in C57BL/6J-APCMin/+ mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/18546290

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

RS5444, a novel PPARgamma agonist, regulates aspects of the differentiated phenotype in nontransformed intestinal epithelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/18546290

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Detection of aberrant crypt foci by magnifying colonoscopy

1 reference

https://pubmed.ncbi.nlm.nih.gov/18546290

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differentiation and reversal of malignant changes in colon cancer through PPARgamma

1 reference

https://pubmed.ncbi.nlm.nih.gov/18546290

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Frequent mutations of the beta-catenin gene in mouse colon tumors induced by azoxymethane

1 reference

https://pubmed.ncbi.nlm.nih.gov/18546290

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Troglitazone, a ligand for peroxisome proliferator-activated receptor gamma, inhibits chemically-induced aberrant crypt foci in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/18546290

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of CS-045, a new oral antidiabetic agent, II. Effects on glycemic control and pancreatic islet structure at a late stage of the diabetic syndrome in C57BL/KsJ-db/db mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/18546290

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1002/IJC.23640

1 reference

Europe PubMed Central

20 August 2017

1 reference

Europe PubMed Central

20 August 2017

1 reference

Europe PubMed Central

20 August 2017

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