Transition-state stabilization in the mechanism of tyrosyl-tRNA synthetase revealed by protein engineering (Q37537194)

20 August 2017

Transition-state stabilization in the mechanism of tyrosyl-tRNA synthetase revealed by protein engineering (English)

1 reference

20 August 2017

2

Fersht AR

1 reference

20 August 2017

Leatherbarrow RJ

1

1 reference

PMCID

390865

20 August 2017

Winter G

series ordinal

3

1 reference

PMCID

390865

20 August 2017

language of work or name

English

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publication date

1 December 1985

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Proceedings of the National Academy of Sciences of the United States of America

20 August 2017

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20 August 2017

82

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20 August 2017

7840-7844

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20 August 2017

23

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Deletion mutagenesis using an ‘M13 splint’: the N-terminal structural domain of tyrosyl-tRNA synthetase (B. stearothermophilus) catalyses the formation of tyrosyl adenylate

20 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=390865

Entropic Contributions to Rate Accelerations in Enzymic and Intramolecular Reactions and the Chelate Effect

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=390865

Hydrogen bonding and biological specificity analysed by protein engineering

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=390865

Binding Energy, Specificity, and Enzymic Catalysis: The Circe Effect

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=390865

Ligand binding and enzymic catalysis coupled through subunits in tyrosyl-tRNA synthetase

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=390865

Catalysis, binding and enzyme-substrate complementarity.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=390865

Demonstration of two reaction pathways for the aminoacylation of tRNA. Application of the pulsed quenched flow technique

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=390865

Redesigning enzyme structure by site-directed mutagenesis: tyrosyl tRNA synthetase and ATP binding

25 June 2018

1 reference

12 December 2020

Probing histidine-substrate interactions in tyrosyl-tRNA synthetase using asparagine and glutamine replacements

1 reference

12 December 2020

Site-directed mutagenesis as a probe of enzyme structure and catalysis: tyrosyl-tRNA synthetase cysteine-35 to glycine-35 mutation

1 reference

12 December 2020

Interaction of crystalline tyrosyl-tRNA synthetase with adenosine, adenosine monophosphate, adenosine triphosphate and pyrophosphate in the presence of tyrosinol

1 reference

12 December 2020

The use of double mutants to detect structural changes in the active site of the tyrosyl-tRNA synthetase (Bacillus stearothermophilus)

1 reference

12 December 2020

Conserved cysteine and histidine residues in the structures of the tyrosyl and methionyl-tRNA synthetases

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.82.23.7840

1 reference

20 August 2017

0 references

1 reference

20 August 2017

1 reference

PMCID

390865