Identification of interspecies difference in hepatobiliary transporters to improve extrapolation of human biliary secretion. (Q37554392)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19611403%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

review article

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title

Identification of interspecies difference in hepatobiliary transporters to improve extrapolation of human biliary secretion (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19611403%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19611403%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

author name string

Yurong Lai

series ordinal

1

1 reference

21 August 2017

language of work or name

English

0 references

publication date

1 October 2009

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19611403%20AND%20SRC:MED&resulttype=core&format=json

Expert Opinion on Drug Metabolism & Toxicology

2 February 2020

published in

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19611403%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

volume

5

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2 February 2020

issue

10

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2 February 2020

page(s)

1175-1187

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19611403%20AND%20SRC:MED&resulttype=core&format=json

The secretory function of the liver: new aspects of hepatobiliary transport

2 February 2020

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21 January 2018

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21 January 2018

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21 January 2018

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Analysis of ABCC6 (MRP6) in normal human tissues

21 January 2018

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Sinusoidal efflux of taurocholate is enhanced in Mrp2-deficient rat liver

21 January 2018

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Evaluation of drug-drug interaction in the hepatobiliary and renal transport of drugs

21 January 2018

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Involvement of Mrp2 (Abcc2) in biliary excretion of moxifloxacin and its metabolites in the isolated perfused rat liver

21 January 2018

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Prediction of drug-induced intrahepatic cholestasis: in vitro screening and QSAR analysis of drugs inhibiting the human bile salt export pump

21 January 2018

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Sex-dependent expression and activity of the ATP-binding cassette transporter breast cancer resistance protein (BCRP/ABCG2) in liver

21 January 2018

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Cloning of novel ABC transporter genes

21 January 2018

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Differential involvement of Mrp2 (Abcc2) and Bcrp (Abcg2) in biliary excretion of 4-methylumbelliferyl glucuronide and sulfate in the rat

21 January 2018

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Involvement of breast cancer resistance protein (BCRP/ABCG2) in the biliary excretion and intestinal efflux of troglitazone sulfate, the major metabolite of troglitazone with a cholestatic effect

21 January 2018

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Cyclosporine markedly raises the plasma concentrations of repaglinide

21 January 2018

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Sirolimus/cyclosporine/tacrolimus interactions on bile flow and biliary excretion of immunosuppressants in a subchronic bile fistula rat model

21 January 2018

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Troglitazone-induced intrahepatic cholestasis by an interference with the hepatobiliary export of bile acids in male and female rats. Correlation with the gender difference in troglitazone sulfate formation and the inhibition of the canalicular bile

21 January 2018

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Possible involvement of the drug transporters P glycoprotein and multidrug resistance-associated protein Mrp2 in disposition of azithromycin

21 January 2018

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Inhibition of biliary glutathione secretion by cyclosporine A in the rat: possible mechanisms and role in the cholestasis induced by the drug.

21 January 2018

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Use of canalicular membrane vesicles (CMVs) from rats, dogs, monkeys and humans to assess drug transport across the canalicular membrane

21 January 2018

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Interspecies pharmacokinetic comparisons and allometric scaling of napsagatran, a low molecular weight thrombin inhibitor

21 January 2018

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Role of transport proteins in drug absorption, distribution and excretion

21 January 2018

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Drug- and estrogen-induced cholestasis through inhibition of the hepatocellular bile salt export pump (Bsep) of rat liver

21 January 2018

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Evaluation of hepatotoxic potential of drugs by inhibition of bile-acid transport in cultured primary human hepatocytes and intact rats

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Disposition and Metabolism of Benoxaprofen in Laboratory Animals and Man

21 January 2018

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Kinetic analyses for species differences in P-glycoprotein-mediated drug transport.

21 January 2018

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Development and characterization of LLC-PK1 cells containing Sprague-Dawley rat Abcb1a (Mdr1a): comparison of rat P-glycoprotein transport to human and mouse

21 January 2018

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Differences in the transport of the antiepileptic drugs phenytoin, levetiracetam and carbamazepine by human and mouse P-glycoprotein

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Functional analysis of mouse and monkey multidrug resistance-associated protein 2 (Mrp2).

21 January 2018

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Functional analysis of dog multidrug resistance-associated protein 2 (Mrp2) in comparison with rat Mrp2.

21 January 2018

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Breast cancer resistance protein (BCRP/ABCG2) is expressed by progenitor cells/reactive ductules and hepatocytes and its expression pattern is influenced by disease etiology and species type: possible functional consequences

21 January 2018

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Tissue distribution and hormonal regulation of the breast cancer resistance protein (Bcrp/Abcg2) in rats and mice

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Hepatic overexpression of murine Abcb11 increases hepatobiliary lipid secretion and reduces hepatic steatosis

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Expression of thirty-six drug transporter genes in human intestine, liver, kidney, and organotypic cell lines.

21 January 2018

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Absolute quantification of multidrug resistance-associated protein 2 (MRP2/ABCC2) using liquid chromatography tandem mass spectrometry

21 January 2018

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21 January 2018

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Variation of peptide transporter (PepT1 and HPT1) expression in Caco-2 cells as a function of cell origin

21 January 2018

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Translational regulation of rat multidrug resistance-associated protein 2 expression is mediated by upstream open reading frames in the 5' untranslated region

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LPS-induced downregulation of MRP2 and BSEP in human liver is due to a posttranscriptional process.

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Differential regulation of the human MRP2 and MRP3 gene expression by glucocorticoids

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Variable expression of MRP2 (ABCC2) in human placenta: influence of gestational age and cellular differentiation.

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Absolute difference of hepatobiliary transporter multidrug resistance-associated protein (MRP2/Mrp2) in liver tissues and isolated hepatocytes from rat, dog, monkey, and human.

21 January 2018

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Targeted proteomics of low-level proteins in human plasma by LC/MSn: using human growth hormone as a model system

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Absolute quantification of specific proteins in complex mixtures using visible isotope-coded affinity tags

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21 January 2018

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Absolute quantification of proteins and phosphoproteins from cell lysates by tandem MS

21 January 2018

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LC-MS/MS mediated absolute quantification and comparison of bile salt export pump and breast cancer resistance protein in livers and hepatocytes across species.

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Localization of P-gp (Abcb1) and Mrp2 (Abcc2) in freshly isolated rat hepatocytes

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A novel method for the determination of biliary clearance in humans

21 January 2018

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Involvement of breast cancer resistance protein (ABCG2) in the biliary excretion mechanism of fluoroquinolones.

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Effect of plasma protein binding on in vitro-in vivo correlation of biliary excretion of drugs evaluated by sandwich-cultured rat hepatocytes

21 January 2018

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In vitro-in vivo correlation of hepatobiliary drug clearance in humans.

21 January 2018

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Physiologically based pharmacokinetic modeling to predict transporter-mediated clearance and distribution of pravastatin in humans

21 January 2018

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Cryopreserved primary hepatocytes as a constantly available in vitro model for the evaluation of human and animal drug metabolism and enzyme induction

21 January 2018

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Human hepatocytes as a tool for studying toxicity and drug metabolism.

21 January 2018

1 reference

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10.1517/17425250903127234

21 January 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19611403%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

1 reference