Prediction of antiepileptic drug efficacy: the use of intracerebral microdialysis to monitor biophase concentrations (Q37554396)

21 August 2017

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title

Prediction of antiepileptic drug efficacy: the use of intracerebral microdialysis to monitor biophase concentrations (English)

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21 August 2017

5

Meindert Danhof

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21 August 2017

Ralph Clinckers

1

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21 August 2017

Ilse Smolders

2

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21 August 2017

Katia Vermoesen

3

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21 August 2017

Yvette Michotte

4

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21 August 2017

Rob Voskuyl

6

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21 August 2017

Oscar Della Pasqua

7

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21 August 2017

language of work or name

English

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publication date

1 October 2009

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Expert Opinion on Drug Metabolism & Toxicology

21 August 2017

published in

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21 August 2017

volume

5

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21 August 2017

issue

10

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21 August 2017

page(s)

1267-1277

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Effectiveness of first antiepileptic drug.

21 August 2017

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Nimodipine restores the altered hippocampal phenytoin pharmacokinetics in a refractory epileptic model.

21 January 2018

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21 January 2018

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Monitoring of ketogenic diet for carnitine metabolites by subcutaneous microdialysis.

21 January 2018

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Microdialysis sampling of carbamazepine, phenytoin and phenobarbital in subcutaneous extracellular fluid and subdural cerebrospinal fluid in humans: an in vitro and in vivo study of adsorption to the sampling device

21 January 2018

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Estimation of topiramate in subdural cerebrospinal fluid, subcutaneous extracellular fluid, and plasma: a single case microdialysis study.

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Blood-brain barrier penetration of felbamate

21 January 2018

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21 January 2018

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Vigabatrin extracellular pharmacokinetics and concurrent gamma-aminobutyric acid neurotransmitter effects in rat frontal cortex and hippocampus using microdialysis

21 January 2018

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21 January 2018

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The use of intracerebral microdialysis to determine changes in blood-brain barrier transport characteristics.

21 January 2018

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Blood—brain barrier permeability during electroshock seizures in the rat

21 January 2018

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21 January 2018

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21 January 2018

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Region-specific overexpression of P-glycoprotein at the blood-brain barrier affects brain uptake of phenytoin in epileptic rats

21 January 2018

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Mechanisms of antiepileptic drug resistance

21 January 2018

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In vivo evidence for P-glycoprotein-mediated transport of phenytoin at the blood-brain barrier of rats

21 January 2018

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Multidrug resistance-associated protein is involved in the regulation of extracellular levels of phenytoin in the brain

21 January 2018

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P-glycoprotein and multidrug resistance-associated protein are involved in the regulation of extracellular levels of the major antiepileptic drug carbamazepine in the brain

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Valproic acid is not a substrate for P-glycoprotein or multidrug resistance proteins 1 and 2 in a number of in vitro and in vivo transport assays

21 January 2018

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Inhibition of multidrug transporters by verapamil or probenecid does not alter blood-brain barrier penetration of levetiracetam in rats

21 January 2018

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Probenecid-inhibitable efflux transport of valproic acid in the brain parenchymal cells of rabbits: a microdialysis study.

21 January 2018

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Impact of efflux transporters and of seizures on the pharmacokinetics of oxcarbazepine metabolite in the rat brain

21 January 2018

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mGlu1 and mGlu5 receptor antagonists lack anticonvulsant efficacy in rodent models of difficult-to-treat partial epilepsy

21 January 2018

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21 January 2018

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Phenytoin concentrations in the human brain: an in vivo microdialysis study

21 January 2018

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21 January 2018

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Comparison of brain extracellular fluid, brain tissue, cerebrospinal fluid, and serum concentrations of antiepileptic drugs measured intraoperatively in patients with intractable epilepsy

21 January 2018

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21 January 2018

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The blood-brain barrier: bottleneck in brain drug development

21 January 2018

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The blood-brain barrier and neurotherapeutics

21 January 2018

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Potential new methods for antiepileptic drug delivery

21 January 2018

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Intranasal midazolam therapy for pediatric status epilepticus

21 January 2018

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Effects of acute and chronic lamotrigine treatment on basal and stimulated extracellular amino acids in the hippocampus of freely moving rats

21 January 2018

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Effect of acute and chronic lamotrigine on basal and stimulated extracellular 5-hydroxytryptamine and dopamine in the hippocampus of the freely moving rat.

21 January 2018

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Hippocampal dopamine and serotonin elevations as pharmacodynamic markers for the anticonvulsant efficacy of oxcarbazepine and 10,11-dihydro-10-hydroxycarbamazepine

21 January 2018

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Norfloxacin-induced electroencephalogram alteration and seizures in rats are not triggered by enhanced levels of intracerebral glutamate

21 January 2018

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Convulsant and subconvulsant doses of norfloxacin in the presence and absence of biphenylacetic acid alter extracellular hippocampal glutamate but not gamma-aminobutyric acid levels in conscious rats

21 January 2018

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An investigation into the pharmacokinetics of 3-mercaptopropionic acid and development of a steady-state chemical seizure model using in vivo microdialysis and electrophysiological monitoring.

21 January 2018

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21 January 2018

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Opening of the blood-brain barrier preceding cortical edema in a severe attack of FHM type II

21 January 2018

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Microdialysis Study of the Neuropharmacokinetics of Phenytoin in Rat Hippocampus and Frontal Cortex

21 January 2018

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10.1517/17425250903146903

21 January 2018

Identifiers

DOI

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21 August 2017

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