Tissue-specific, non-invasive toxicity biomarkers: translation from preclinical safety assessment to clinical safety monitoring (Q37554404)

21 August 2017

1 reference

title

Tissue-specific, non-invasive toxicity biomarkers: translation from preclinical safety assessment to clinical safety monitoring (English)

1 reference

21 August 2017

0 references

0 references

Patrick Y Muller

1

1 reference

21 August 2017

Frank Dieterle

series ordinal

2

1 reference

21 August 2017

language of work or name

English

0 references

publication date

1 September 2009

1 reference

Expert Opinion on Drug Metabolism & Toxicology

21 August 2017

published in

1 reference

21 August 2017

volume

5

1 reference

21 August 2017

issue

9

1 reference

21 August 2017

page(s)

1023-1038

1 reference

Biomarkers and surrogate endpoints: preferred definitions and conceptual framework

21 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1517%2F17425250903114174

The current state of serum biomarkers of hepatotoxicity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903114174

Fit-for-purpose method development and validation for successful biomarker measurement.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903114174

Recommendations for the bioanalytical method validation of ligand-binding assays to support pharmacokinetic assessments of macromolecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903114174

Bioanalytical method validation for macromolecules in support of pharmacokinetic studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903114174

Quantitative bioanalytical methods validation and implementation: best practices for chromatographic and ligand binding assays

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903114174

Biomarker qualification pilot process at the US Food and Drug Administration

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903114174

Strategic approach to fit-for-purpose biomarkers in drug development

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903114174

Monitoring liver safety in drug development: the GSK experience.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903114174

Liver enzyme alteration: a guide for clinicians.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903114174

Marked elevation of serum mitochondrion-derived markers in mild models of non-alcoholic steatohepatitis in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903114174

Comparison of plasma alpha glutathione S-transferase concentrations during and after low-flow sevoflurane or isoflurane anaesthesia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903114174

Idiosyncratic drug hepatotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903114174

Statins and hepatotoxicity: focus on patients with fatty liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903114174

Drug-induced glomerulopathies

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903114174

Impaired tubular uptake explains albuminuria in early diabetic nephropathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903114174

Urinary kidney injury molecule-1: a sensitive quantitative biomarker for early detection of kidney tubular injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903114174

Neutrophil gelatinase-associated lipocalin: a novel early urinary biomarker for cisplatin nephrotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903114174

Neutrophil gelatinase-associated lipocalin (NGAL) as a biomarker for acute renal injury after cardiac surgery

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903114174

Kidney slices of human and rat to characterize cisplatin-induced injury on cellular pathways and morphology

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903114174

Assessment of effective renal plasma flow, enzymuria, and cytokine release in healthy volunteers receiving a single dose of amphotericin B desoxycholate

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903114174

Urinary pi-class glutathione transferase as an indicator of tubular damage in the human kidney.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903114174

Urinary cystatin C as a specific marker of tubular dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903114174

Serum cystatin C is superior to serum creatinine as a marker of kidney function: a meta-analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903114174

Biomarkers of acute renal injury and renal failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903114174

Drug-induced phospholipidosis: issues and future directions

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903114174

Cationic amphiphilic drug-induced phospholipidosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903114174

Drug-induced phospholipidosis is caused by blockade of mannose 6-phosphate receptor-mediated targeting of lysosomal enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903114174

A toxicogenomic approach to drug-induced phospholipidosis: analysis of its induction mechanism and establishment of a novel in vitro screening system

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903114174

Characterisation of a potential biomarker of phospholipidosis from amiodarone-treated rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903114174

Biomarkers to monitor drug-induced phospholipidosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903114174

Phenylacetylglycine, a putative biomarker of phospholipidosis: its origins and relevance to phospholipid accumulation using amiodarone treated rats as a model

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903114174

Cardiotoxicity in rats induced by methidathion and ameliorating effect of vitamins E and C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903114174

Comparison of the diagnostic value of cardiac troponin I and T determinations for detecting early myocardial damage and the relationship with histological findings after isoprenaline-induced cardiac injury in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903114174

Cardiac troponin I as a predictor of major cardiac events in emergency department patients with acute chest pain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903114174

Cardiac troponin T in acute coronary syndrome with renal insufficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903114174

Brain natriuretic peptide is a predictor of anthracycline-induced cardiotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903114174

Troponin-T and brain natriuretic peptide as predictors for adriamycin-induced cardiomyopathy in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903114174

N-terminal fragment of B-type natriuretic peptide (NT-proBNP), a marker of cardiac safety during antipsychotic treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903114174

N-terminal pro-B-type natriuretic peptide after high-dose chemotherapy: a marker predictive of cardiac dysfunction?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903114174

Changes in circulating and testicular levels of inhibin A and B and activin A during postnatal development in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903114174

Preservation of fertility and ovarian function and minimalization of chemotherapy associated gonadotoxicity and premature ovarian failure: the role of inhibin-A and -B as markers

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903114174

Drug-induced vascular injury--a quest for biomarkers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903114174

The toxicity of SCH 351591, a novel phosphodiesterase-4 inhibitor, in Cynomolgus monkeys

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903114174

An update and appraisal of the cilomilast Phase III clinical development programme for chronic obstructive pulmonary disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903114174

Induced secretion of tissue inhibitor of metalloproteinases-1 (TIMP-1) in vivo and in vitro by hepatotoxin rubratoxin B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903114174

Comparative analysis of novel noninvasive renal biomarkers and metabonomic changes in a rat model of gentamicin nephrotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903114174

Novel insights into vascular calcification

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903114174

The circulating inactive form of matrix Gla Protein (ucMGP) as a biomarker for cardiovascular calcification

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903114174

Biomarkers of drug-induced vascular injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903114174

Urinary excretion of trypsinogen activation peptide (TAP) in taurocholate-induced pancreatitis in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903114174

Immunohistologic localization of alpha, mu, and pi class glutathione S-transferases in human tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903114174

Urinary clusterin levels in the rat correlate with the severity of tubular damage and may help to differentiate between glomerular and tubular injuries

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903114174

Cadmium nephrotoxicity and evacuation from the body in a rat modeled subchronic intoxication.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903114174

Renal tubular toxicity associated with tenofovir assessed using urine-beta 2 microglobulin, percentage of tubular reabsorption of phosphate and alkaline phosphatase levels

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903114174

Urine NGAL predicts severity of acute kidney injury after cardiac surgery: a prospective study

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903114174

10.1517/17425250903114174

21 January 2018

Identifiers

DOI

1 reference

21 August 2017

1 reference