Loss of SS18-SSX1 inhibits viability and induces apoptosis in synovial sarcoma (Q37563723)

21 August 2017

Loss of SS18-SSX1 inhibits viability and induces apoptosis in synovial sarcoma (English)

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21 August 2017

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Emily E Carmody Soni

1

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21 August 2017

Silke Schlottman

2

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21 August 2017

Hayriye V Erkizan

3

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21 August 2017

Aykut Uren

4

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21 August 2017

Jeffrey A Toretsky

5

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21 August 2017

language of work or name

English

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publication date

1 March 2014

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Clinical Orthopaedics and Related Research

21 August 2017

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21 August 2017

472

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21 August 2017

3

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21 August 2017

874-882

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describes a project that uses

21 August 2017

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3916608/fullTextXML

inferred from PubMed Central ID database lookup

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Differentially regulated splice variants and systems biology analysis of Kaposi's sarcoma-associated herpesvirus-infected lymphatic endothelial cells

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23 August 2017

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The SYT-SSX fusion protein down-regulates the cell proliferation regulator COM1 in t(x;18) synovial sarcoma

23 August 2017

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Synovial sarcoma: a retrospective analysis of 271 patients of all ages treated at a single institution

23 August 2017

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Conserved SNH domain of the proto-oncoprotein SYT interacts with components of the human chromatin remodelling complexes, while the QPGY repeat domain forms homo-oligomers

23 August 2017

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23 August 2017

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Cloning and characterization of spliced fusion transcript variants of synovial sarcoma: SYT/SSX4, SYT/SSX4v, and SYT/SSX2v. Possible regulatory role of the fusion gene product in wild type SYT expression

23 August 2017

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Identification of a novel spliced variant of the SYT gene expressed in normal tissues and in synovial sarcoma

23 August 2017

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Synovial sarcoma: a clinicopathologic, staging, and prognostic assessment

23 August 2017

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Synovial sarcoma: a multivariate analysis of prognostic factors in 112 patients with primary localized tumors of the extremity

23 August 2017

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A novel fusion gene, SYT-SSX4, in synovial sarcoma.

23 August 2017

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SYT-SSX gene fusion as a determinant of morphology and prognosis in synovial sarcoma

23 August 2017

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SSX: a multigene family with several members transcribed in normal testis and human cancer

23 August 2017

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The SYT protein involved in the t(X;18) synovial sarcoma translocation is a transcriptional activator localised in nuclear bodies

23 August 2017

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Nuclear localization of SYT, SSX and the synovial sarcoma-associated SYT-SSX fusion proteins

23 August 2017

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Identification of novel genes, SYT and SSX, involved in the t(X;18)(p11.2;q11.2) translocation found in human synovial sarcoma

23 August 2017

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Fusion of SYT to two genes, SSX1 and SSX2, encoding proteins with homology to the Kruppel-associated box in human synovial sarcoma

23 August 2017

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Molecular diagnosis of synovial sarcoma and characterization of a variant SYT-SSX2 fusion transcript

23 August 2017

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The natural history of metastatic synovial sarcoma: experience of the Southwest Oncology group

23 August 2017

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23 August 2017

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Downregulation of SS18-SSX1 expression in synovial sarcoma by small interfering RNA enhances the focal adhesion pathway and inhibits anchorage-independent growth in vitro and tumor growth in vivo.

6 September 2017

1 reference

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Downregulation of SS18-SSX1 expression by small interfering RNA inhibits growth and induces apoptosis in human synovial sarcoma cell line HS-SY-II in vitro

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3916608

The oncoprotein SS18-SSX1 promotes p53 ubiquitination and degradation by enhancing HDM2 stability.

14 September 2017

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A variant of the SYT-SSX2 fusion gene in a case of synovial sarcoma

14 September 2017

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A randomised phase II study on neo-adjuvant chemotherapy for 'high-risk' adult soft-tissue sarcoma

14 September 2017

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Synovial sarcoma outcome following conservation surgery and radiotherapy

14 September 2017

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Novel fluorescent ligase detection reaction and flow cytometric analysis of SYT-SSX fusions in synovial sarcoma

14 September 2017

1 reference

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Detection of SS18-SSX fusion transcripts in formalin-fixed paraffin-embedded neoplasms: analysis of conventional RT-PCR, qRT-PCR and dual color FISH as diagnostic tools for synovial sarcoma.

25 June 2018

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Expression of mRNA for growth hormone-releasing hormone and splice variants of GHRH receptors in human malignant bone tumors

1 September 2018

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The SYT-SSX1 variant of synovial sarcoma is associated with a high rate of tumor cell proliferation and poor clinical outcome.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3916608

Isolation and characterization of the mouse homolog of SYT, a gene implicated in the development of human synovial sarcomas.

1 September 2018

1 reference

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Novel mdm2 splice variants identified in pediatric rhabdomyosarcoma tumors and cell lines

1 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23716114

12 December 2020

inferred from PubMed ID database lookup

A consistent chromosome translocation in synovial sarcoma

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23716114

12 December 2020

inferred from PubMed ID database lookup

Diagnosis of synovial sarcoma with the reverse transcriptase-polymerase chain reaction: analyses of 84 soft tissue and bone tumors

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23716114

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1007/S11999-013-3065-9

1 reference

21 August 2017

1 reference

21 August 2017

PubMed publication ID

23716114

1 reference