Activation of naïve CD4 T cells by anti-CD3 reveals an important role for Fyn in Lck-mediated signaling (Q37571291)

21 August 2017

Activation of naïve CD4 T cells by anti-CD3 reveals an important role for Fyn in Lck-mediated signaling (English)

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21 August 2017

Katsuji Sugie

1

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21 August 2017

Myung-Shin Jeon

series ordinal

2

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21 August 2017

Howard M Grey

series ordinal

3

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21 August 2017

language of work or name

English

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publication date

1 October 2004

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Proceedings of the National Academy of Sciences of the United States of America

21 August 2017

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21 August 2017

101

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21 August 2017

41

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21 August 2017

14859-14864

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Spontaneous proliferation, a response of naive CD4 T cells determined by the diversity of the memory cell repertoire.

21 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=522036

Fyn and PTP-PEST-mediated regulation of Wiskott-Aldrich syndrome protein (WASp) tyrosine phosphorylation is required for coupling T cell antigen receptor engagement to WASp effector function and T cell activation

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=522036

Regulation of Fyn Through Translocation of Activated Lck into Lipid Rafts

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=522036

Homeostatic T cell proliferation in a T cell-dendritic cell coculture system

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=522036

Organization of plasma membrane functional rafts upon T cell activation

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=522036

T-cell receptor antagonists induce Vav phosphorylation by selective activation of Fyn kinase

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=522036

The Src family tyrosine kinase Fyn regulates natural killer T cell development

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=522036

FYN-T-FYB-SLP-76 interactions define a T-cell receptor zeta/CD3-mediated tyrosine phosphorylation pathway that up-regulates interleukin 2 transcription in T-cells

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=522036

Fyn and ZAP-70 are required for Vav phosphorylation in T cells stimulated by antigen-presenting cells

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=522036

Antigen-dependent and -independent Ca2+ responses triggered in T cells by dendritic cells compared with B cells

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=522036

Differential activation of transcription factors induced by Ca2+ response amplitude and duration

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=522036

Tyrosine phosphorylation of Pyk2 is selectively regulated by Fyn during TCR signaling

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=522036

Signal transduction by lymphocyte antigen receptors

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=522036

Association of the fyn protein-tyrosine kinase with the T-cell antigen receptor

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=522036

Profound block in thymocyte development in mice lacking p56lck

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=522036

Defective T cell receptor signaling in mice lacking the thymic isoform of p59fyn

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=522036

Differential T-cell antigen receptor signaling mediated by the Src family kinases Lck and Fyn.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=522036

T-cell receptor stimulation elicits an early phase of activation and a later phase of deactivation of the transcription factor NFAT1.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=522036

Enumeration, phenotyping, and identification of activation events in conjugates between T cells and antigen-presenting cells by flow cytometry

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=522036

p59fyn tyrosine kinase regulates p56lck tyrosine kinase activity and early TCR-mediated signaling.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=522036

Cutting edge: Fyn is essential for tyrosine phosphorylation of Csk-binding protein/phosphoprotein associated with glycolipid-enriched microdomains in lipid rafts in resting T cells.

28 September 2017

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0406168101

The Src family kinase Fyn mediates signals induced by TCR antagonists

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0406168101

Cutting edge: NKT cell development is selectively impaired in Fyn- deficient mice.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=522036

T cells expressing receptors of different affinity for antigen ligands reveal a unique role for p59fyn in T cell development and optimal stimulation of T cells by antigen

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=522036

Naive versus memory CD4 T cell response to antigen. Memory cells are less dependent on accessory cell costimulation and can respond to many antigen-presenting cell types including resting B cells

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=522036

Heterogeneity among T cells in intracellular free calcium responses after mitogen stimulation with PHA or anti-CD3. Simultaneous use of indo-1 and immunofluorescence with flow cytometry

1 September 2018

1 reference

12 December 2020

Involvement of the same region of the T cell antigen receptor in thymic selection and foreign peptide recognition

1 reference

12 December 2020

pp59fyn mutant mice display differential signaling in thymocytes and peripheral T cells

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12 December 2020

Differential T cell signaling induced by antagonist peptide-MHC complexes and the associated phenotypic responses

1 reference

12 December 2020

The minimal number of antigen-major histocompatibility complex class II complexes required for activation of naive and primed T cells

1 reference

12 December 2020

TCR antagonist peptides induce formation of APC-T cell conjugates and activate a Rac signaling pathway

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.0406168101

1 reference

21 August 2017

0 references

1 reference

21 August 2017

PubMed publication ID

15465914

1 reference