SGLT2 inhibitor empagliflozin reduces renal growth and albuminuria in proportion to hyperglycemia and prevents glomerular hyperfiltration in diabetic Akita mice. (Q37575455)

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English	SGLT2 inhibitor empagliflozin reduces renal growth and albuminuria in proportion to hyperglycemia and prevents glomerular hyperfiltration in diabetic Akita mice.	scientific article

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29 February 2020

SGLT2 inhibitor empagliflozin reduces renal growth and albuminuria in proportion to hyperglycemia and prevents glomerular hyperfiltration in diabetic Akita mice (English)

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29 February 2020

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29 February 2020

Takahiro Masuda

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author name string

Maria Gerasimova

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29 February 2020

Michael A Rose

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29 February 2020

Joseph Satriano

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Eric Mayoux

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29 February 2020

Hermann Koepsell

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29 February 2020

Scott C Thomson

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13 November 2013

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29 February 2020

American Journal of Physiology - Renal Physiology

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306

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29 February 2020

F194-204

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29 February 2020

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29 February 2020

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Increase in SGLT1-mediated transport explains renal glucose reabsorption during genetic and pharmacological SGLT2 inhibition in euglycemia.

1 reference

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23 August 2017

A High-throughput method for measurement of glomerular filtration rate in conscious mice

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23 August 2017

Knockout of Na-glucose transporter SGLT2 attenuates hyperglycemia and glomerular hyperfiltration but not kidney growth or injury in diabetes mellitus

1 reference

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23 August 2017

Renal function in diabetic disease models: the tubular system in the pathophysiology of the diabetic kidney

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Na(+)-D-glucose cotransporter SGLT1 is pivotal for intestinal glucose absorption and glucose-dependent incretin secretion

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23 August 2017

Empagliflozin, a novel selective sodium glucose cotransporter-2 (SGLT-2) inhibitor: characterisation and comparison with other SGLT-2 inhibitors

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Acute and chronic effects of SGLT2 blockade on glomerular and tubular function in the early diabetic rat

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The proximal tubule in the pathophysiology of the diabetic kidney

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The Sweet Pee model for Sglt2 mutation

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23 August 2017

SGLT2 mediates glucose reabsorption in the early proximal tubule.

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Familial renal glucosuria and SGLT2: from a mendelian trait to a therapeutic target.

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23 August 2017

Sodium glucose cotransporter 2 inhibitors as a new treatment for diabetes mellitus.

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A novel missense mutation in SLC5A2 encoding SGLT2 underlies autosomal-recessive renal glucosuria and aminoaciduria

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Ornithine decarboxylase, kidney size, and the tubular hypothesis of glomerular hyperfiltration in experimental diabetes

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Long-term treatment with empagliflozin, a novel, potent and selective SGLT-2 inhibitor, improves glycaemic control and features of metabolic syndrome in diabetic rats.

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12 December 2020

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Persistent renal hypertrophy and faster decline of glomerular filtration rate precede the development of microalbuminuria in type 1 diabetes

1 reference

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12 December 2020

based on heuristic

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Adenosine A(1) receptors determine glomerular hyperfiltration and the salt paradox in early streptozotocin diabetes mellitus

1 reference

https://pubmed.ncbi.nlm.nih.gov/24226524

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glomerular hyperfiltration in experimental diabetes mellitus: potential role of tubular reabsorption

1 reference

https://pubmed.ncbi.nlm.nih.gov/24226524

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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1 reference

https://pubmed.ncbi.nlm.nih.gov/24226524

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based on heuristic

inferred from PubMed ID database lookup

Relationship between kidney volume, microalbuminuria and duration of diabetes mellitus

1 reference

https://pubmed.ncbi.nlm.nih.gov/24226524

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based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1152/AJPRENAL.00520.2013

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29 February 2020

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29 February 2020

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29 February 2020

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