Functional correlation of P-glycoprotein expression and genotype with expression of the human immunodeficiency virus type 1 coreceptor CXCR4. (Q37583423)

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English	Functional correlation of P-glycoprotein expression and genotype with expression of the human immunodeficiency virus type 1 coreceptor CXCR4.	scientific article

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4 January 2020

Functional correlation of P-glycoprotein expression and genotype with expression of the human immunodeficiency virus type 1 coreceptor CXCR4 (English)

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4 January 2020

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4 January 2020

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4 January 2020

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Becky Chandler

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4 January 2020

Patrick G Bray

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4 January 2020

C Anthony Hart

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4 January 2020

David J Back

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4 January 2020

Saye H Khoo

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4 January 2020

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1 November 2004

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4 January 2020

Journal of Virology

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4 January 2020

78

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21

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4 January 2020

12022-12029

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4 January 2020

Cytopathicity of human immunodeficiency virus type 1 primary isolates depends on coreceptor usage and not patient disease status

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=523248

23 August 2017

An overview of the determinants of CCR5 and CXCR4 co-receptor function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=523248

23 August 2017

In vitro and in vivo reversal of P-glycoprotein-mediated multidrug resistance by a novel potent modulator, XR9576.

1 reference

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23 August 2017

Symmetry and structure in P-glycoprotein and ABC transporters what goes around comes around

1 reference

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23 August 2017

Use of inhibitors to evaluate coreceptor usage by simian and simian/human immunodeficiency viruses and human immunodeficiency virus type 2 in primary cells

1 reference

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23 August 2017

Human immunodeficiency virus type 1 coreceptor preferences determine target T-cell depletion and cellular tropism in human lymphoid tissue

1 reference

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23 August 2017

Viral entry through CXCR4 is a pathogenic factor and therapeutic target in human immunodeficiency virus type 1 disease

1 reference

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23 August 2017

Will multiple coreceptors need to be targeted by inhibitors of human immunodeficiency virus type 1 entry?

1 reference

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23 August 2017

CXCR4 utilization is sufficient to trigger CD4+ T cell depletion in HIV-1-infected human lymphoid tissue

1 reference

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23 August 2017

Human immunodeficiency virus protease inhibitors serve as substrates for multidrug transporter proteins MDR1 and MRP1 but retain antiviral efficacy in cell lines expressing these transporters

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=523248

23 August 2017

Use of coreceptors other than CCR5 by non-syncytium-inducing adult and pediatric isolates of human immunodeficiency virus type 1 is rare in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=523248

23 August 2017

In vivo evolution of HIV-1 co-receptor usage and sensitivity to chemokine-mediated suppression.

1 reference

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23 August 2017

Change in coreceptor use correlates with disease progression in HIV-1--infected individuals

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=523248

23 August 2017

High frequency of syncytium-inducing and CXCR4-tropic viruses among human immunodeficiency virus type 1 subtype C-infected patients receiving antiretroviral treatment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=523248

6 September 2017

μ-opioid modulation of HIV-1 coreceptor expressionand HIV-1 replication

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=523248

6 September 2017

Effect of ABC transporters on HIV-1 infection: inhibition of virus production by the MDR1 transporter

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=523248

6 September 2017

Primary, syncytium-inducing human immunodeficiency virus type 1 isolates are dual-tropic and most can use either Lestr or CCR5 as coreceptors for virus entry

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=523248

6 September 2017

Biological phenotype of human immunodeficiency virus type 1 clones at different stages of infection: progression of disease is associated with a shift from monocytotropic to T-cell-tropic virus population

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=523248

6 September 2017

Membrane raft microdomains mediate lateral assemblies required for HIV-1 infection

1 reference

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28 September 2017

P-glycoprotein limits oral availability, brain, and fetal penetration of saquinavir even with high doses of ritonavir

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=523248

28 September 2017

Verapamil suppressed lymphocyte adhesion to vascular endothelial cells via selective inhibition of VCAM-1 expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=523248

28 September 2017

Adaptation to promiscuous usage of CC and CXC-chemokine coreceptors in vivo correlates with HIV-1 disease progression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=523248

28 September 2017

A simplified approach to determining P-glycoprotein expression in peripheral blood mononuclear cell subsets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=523248

25 June 2018

P-glycoprotein expression by peripheral blood mononuclear cells from human immunodeficiency virus-infected patients is independent from response to highly active antiretroviral therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=523248

25 June 2018

Combinations of P-glycoprotein blockers, verapamil, PSC833, and cremophor act differently on the multidrug resistance associated protein (MRP) and on P-glycoprotein (Pgp).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=523248

25 June 2018

Saquinavir soft-gel capsule formulation. A review of its use in patients with HIV infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=523248

25 June 2018

Prognostic value of HIV-1 syncytium-inducing phenotype for rate of CD4+ cell depletion and progression to AIDS.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=523248

25 June 2018

The effects of protease inhibitors and nonnucleoside reverse transcriptase inhibitors on p-glycoprotein expression in peripheral blood mononuclear cells in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=523248

1 September 2018

Differential expression of human immunodeficiency virus coreceptors, by CEM, CEMVBL, and CEM E1000 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=523248

1 September 2018

Differential effects of p-glycoprotein and multidrug resistance protein-1 on productive human immunodeficiency virus infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=523248

1 September 2018

Changes in CCR5 and CXCR4 expression and beta-chemokine production in HIV-1-infected patients treated with highly active antiretroviral therapy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=523248

1 September 2018

CYP3A4-mediated hepatic metabolism of the HIV-1 protease inhibitor saquinavir in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=523248

1 September 2018

Response to antiretroviral treatment in HIV-1-infected individuals with allelic variants of the multidrug resistance transporter 1: a pharmacogenetics study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=523248

1 September 2018

P-glycoprotein-overexpressing multidrug-resistant cells are resistant to infection by enveloped viruses that enter via the plasma membrane

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=523248

1 September 2018

Emergence of syncytium-inducing human immunodeficiency virus type 1 variants coincides with a transient increase in viral RNA level and is an independent predictor for progression to AIDS.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=523248

1 September 2018

Modulation of P-glycoprotein function in human lymphocytes and Caco-2 cell monolayers by HIV-1 protease inhibitors.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15479841

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enhanced expression of the CXCR4 co-receptor in HIV-1-infected individuals correlates with the emergence of syncytia-inducing strains

1 reference

https://pubmed.ncbi.nlm.nih.gov/15479841

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The C3435T mutation in the human MDR1 gene is associated with altered efflux of the P-glycoprotein substrate rhodamine 123 from CD56+ natural killer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/15479841

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Allele frequency of three functionally active polymorphisms of the MDR-1 gene in high-risk HIV-negative and HIV-positive Caucasians

1 reference

https://pubmed.ncbi.nlm.nih.gov/15479841

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Influence of polymorphisms within the CX3CR1 and MDR-1 genes on initial antiretroviral therapy response

1 reference

https://pubmed.ncbi.nlm.nih.gov/15479841

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NF-kappaB promotes breast cancer cell migration and metastasis by inducing the expression of the chemokine receptor CXCR4

1 reference

https://pubmed.ncbi.nlm.nih.gov/15479841

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MDR1 C3435T genetic polymorphism does not influence the response to antiretroviral therapy in drug-naive HIV-positive patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/15479841

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Verapamil selectively inhibits expression of interleukin-2 messenger RNA in mitogen activated mononuclear blood cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/15479841

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transcriptional modulation of human IL-6 gene expression by verapamil

1 reference

https://pubmed.ncbi.nlm.nih.gov/15479841

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chemosensitization and drug accumulation effects of VX-710, verapamil, cyclosporin A, MS-209 and GF120918 in multidrug resistant HL60/ADR cells expressing the multidrug resistance-associated protein MRP

1 reference

https://pubmed.ncbi.nlm.nih.gov/15479841

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selective inhibition of vascular cell adhesion molecule-1 expression by verapamil in human vascular endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/15479841

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HIV protease inhibitors, saquinavir, indinavir and ritonavir: inhibition of CYP3A4-mediated metabolism of testosterone and benzoxazinorifamycin, KRM-1648, in human liver microsomes

1 reference

https://pubmed.ncbi.nlm.nih.gov/15479841

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HIV entry and tropism. When one receptor is not enough

1 reference

https://pubmed.ncbi.nlm.nih.gov/15479841

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/JVI.78.21.12022-12029.2004

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4 January 2020

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24 November 2022

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4 January 2020

PubMed publication ID

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4 January 2020

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