A role for TGFbeta signaling in the pathogenesis of psoriasis (Q37587746)

21 August 2017

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title

A role for TGFbeta signaling in the pathogenesis of psoriasis (English)

1 reference

21 August 2017

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Gangwen Han

1

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21 August 2017

Cortny A Williams

2

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21 August 2017

Kelli Salter

3

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21 August 2017

Pamela J Garl

4

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21 August 2017

Allen G Li

5

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21 August 2017

Xiao-Jing Wang

6

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21 August 2017

language of work or name

English

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publication date

27 August 2009

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Journal of Investigative Dermatology

21 August 2017

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21 August 2017

130

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21 August 2017

2

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21 August 2017

371-377

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Long-term data in the treatment of psoriasis

21 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898194

IL-21 and TGF-beta are required for differentiation of human T(H)17 cells

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898194

T-helper 17 cells in psoriatic plaques and additional genetic links between IL-23 and psoriasis

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898194

Three decades of psoriasis research: where has it led us?

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898194

TGF-beta-induced fibrosis and SMAD signaling: oligo decoys as natural therapeutics for inhibition of tissue fibrosis and scarring

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898194

Development, cytokine profile and function of human interleukin 17-producing helper T cells

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898194

Pathogenesis and clinical features of psoriasis

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898194

Potential complications associated with the use of biologic agents for psoriasis

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898194

Mouse models of psoriasis.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898194

Genetic variants of Tgfb1 act as context-dependent modifiers of mouse skin tumor susceptibility.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898194

Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898194

Transforming growth factor-beta induces development of the T(H)17 lineage

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898194

TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898194

Current view of the role of transforming growth factor beta 1 in skin carcinogenesis

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898194

Psoriasis-like skin disease and arthritis caused by inducible epidermal deletion of Jun proteins

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898194

Distinct mechanisms of TGF-beta1-mediated epithelial-to-mesenchymal transition and metastasis during skin carcinogenesis

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898194

Latent TGFbeta1 overexpression in keratinocytes results in a severe psoriasis-like skin disorder

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898194

Peroxisome proliferator-activated receptor-gamma: therapeutic target for diseases beyond diabetes: quo vadis?

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898194

A role for endogenous transforming growth factor beta 1 in Langerhans cell biology: the skin of transforming growth factor beta 1 null mice is devoid of epidermal Langerhans cells

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898194

Transforming growth factor beta 1 null mutation in mice causes excessive inflammatory response and early death

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898194

Mechanism of activation of the TGF-beta receptor

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898194

Recombinant latent transforming growth factor beta 1 has a longer plasma half-life in rats than active transforming growth factor beta 1, and a different tissue distribution

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898194

RAG-1-deficient mice have no mature B and T lymphocytes

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898194

Targeted disruption of the mouse transforming growth factor-beta 1 gene results in multifocal inflammatory disease

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898194

Keratinocytes produce and are regulated by transforming growth factors

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898194

Expression of TGF-beta related Smad proteins in human epithelial skin tumors.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898194

Disruption of transforming growth factor beta signaling and profibrotic responses in normal skin fibroblasts by peroxisome proliferator-activated receptor gamma

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898194

Down-regulation of transforming growth factor-beta receptors I and II is seen in lesional but not non-lesional psoriatic epidermis

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898194

Identification and activation of latent transforming growth factor beta

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898194

Overexpression of transforming growth factor beta1 in head and neck epithelia results in inflammation, angiogenesis, and epithelial hyperproliferation

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898194

Serum concentrations of transforming growth factor beta 1 in patients with psoriasis vulgaris

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898194

Plasma transforming growth factor β1as a biomarker of psoriasis activity and treatment efficacy

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898194

Ultraviolet irradiation alters transforming growth factor beta/smad pathway in human skin in vivo

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898194

TGF beta signaling in health and disease

1 September 2018

1 reference

12 December 2020

Plasma TGF-beta1, TIMP-1, MMP-1 and IL-18 as a combined biomarker of psoriasis activity

1 reference

12 December 2020

Association between psoriasis severity and transforming growth factor beta(1) and beta (2) in plasma and scales from psoriatic lesions

1 reference

12 December 2020

Downregulation of TGFβ isoforms and their receptors contributes to keratinocyte hyperproliferation in psoriasis vulgaris

1 reference

12 December 2020

Differential localization of TGF-beta-precursor isotypes in normal human skin

1 reference

12 December 2020

Langerhans cells in the TGF beta 1 null mouse

1 reference

12 December 2020

Mouse models: psoriasis: an epidermal disease after all?

1 reference

12 December 2020

Keratinocytes regain momentum as instigators of cutaneous inflammation

1 reference

12 December 2020

Psoriasis Vulgaris Lesions Contain Discrete Populations of Th1 and Th17 T Cells

1 reference

12 December 2020

Interleukin-10: an important immunoregulatory cytokine with major impact on psoriasis

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.252

7 January 2021

Suprabasal expression of human amphiregulin in the epidermis of transgenic mice induces a severe, early-onset, psoriasis-like skin pathology: expression of amphiregulin in the basal epidermis is also associated with synovitis

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.252

7 January 2021

The IL-23/Th17 axis in the immunopathogenesis of psoriasis

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.252

7 January 2021

Interleukin-4 therapy of psoriasis induces Th2 responses and improves human autoimmune disease

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.252

7 January 2021

Response of psoriasis to a lymphocyte-selective toxin (DAB389IL-2) suggests a primary immune, but not keratinocyte, pathogenic basis

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.252

7 January 2021

Induction of IL-17+ T cell trafficking and development by IFN-gamma: mechanism and pathological relevance in psoriasis

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.252

7 January 2021

The role of Smads in skin development.

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.252

7 January 2021

Stat3 links activated keratinocytes and immunocytes required for development of psoriasis in a novel transgenic mouse model

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.252

7 January 2021

Amelioration of epidermal hyperplasia by TNF inhibition is associated with reduced Th17 responses

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.252

7 January 2021

Identifiers

DOI

10.1038/JID.2009.252

1 reference

21 August 2017

1 reference

21 August 2017

PubMed publication ID

19710682

1 reference