Therapeutic peptides for cancer therapy. Part II - cell cycle inhibitory peptides and apoptosis-inducing peptides (Q37594770)

21 August 2017

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title

Therapeutic peptides for cancer therapy. Part II - cell cycle inhibitory peptides and apoptosis-inducing peptides (English)

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21 August 2017

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Drazen Raucher

1

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21 August 2017

Shama Moktan

series ordinal

2

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21 August 2017

Iqbal Massodi

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3

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21 August 2017

Gene L Bidwell

series ordinal

4

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21 August 2017

language of work or name

English

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publication date

1 October 2009

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Expert Opinion on Drug Delivery

21 August 2017

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21 August 2017

6

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21 August 2017

10

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21 August 2017

1049-1064

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Transmembrane transport of peptide type compounds: prospects for oral delivery

21 August 2017

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https://api.crossref.org/works/10.1517%2F17425240903158909

Inhibition of nuclear translocation of transcription factor NF-kappa B by a synthetic peptide containing a cell membrane-permeable motif and nuclear localization sequence

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903158909

A brief introduction to cell-penetrating peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903158909

Intracellular delivery of large molecules and small particles by cell-penetrating proteins and peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903158909

Membrane disrupting lytic peptides for cancer treatments

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903158909

A small peptide inhibitor of DNA replication defines the site of interaction between the cyclin-dependent kinase inhibitor p21WAF1 and proliferating cell nuclear antigen

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903158909

Tracking the in vivo fate of recombinant polypeptides by isotopic labeling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903158909

Tumor accumulation, degradation and pharmacokinetics of elastin-like polypeptides in nude mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903158909

Thermal cycling enhances the accumulation of a temperature-sensitive biopolymer in solid tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903158909

Evaluation of cell penetrating peptides fused to elastin-like polypeptide for drug delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903158909

Translocating proline-rich peptides from the antimicrobial peptide bactenecin 7.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903158909

Inhibition of pRb phosphorylation and cell-cycle progression by a 20-residue peptide derived from p16CDKN2/INK4A

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903158909

Characterization of the cyclin-dependent kinase inhibitory domain of the INK4 family as a model for a synthetic tumour suppressor molecule

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903158909

An N-terminal p14ARF peptide blocks Mdm2-dependent ubiquitination in vitro and can activate p53 in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903158909

Potent synergy of dual antitumor peptides for growth suppression of human glioblastoma cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903158909

The p16(INK4a) tumour suppressor protein inhibits alphavbeta3 integrin-mediated cell spreading on vitronectin by blocking PKC-dependent localization of alphavbeta3 to focal contacts

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903158909

Changes in motility, gene expression and actin dynamics: Cdk6-induced cytoskeletal changes associated with differentiation in mouse astrocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903158909

Anti-migratory and anti-angiogenic effect of p16: a novel localization at membrane ruffles and lamellipodia in endothelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903158909

Design of a novel class of peptide inhibitors of cyclin-dependent kinase/cyclin activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903158909

Identification of a cyclin-cdk2 recognition motif present in substrates and p21-like cyclin-dependent kinase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903158909

Selective killing of transformed cells by cyclin/cyclin-dependent kinase 2 antagonists

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903158909

Retinoblastoma protein contains a C-terminal motif that targets it for phosphorylation by cyclin-cdk complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903158909

Molecular cloning of the akt oncogene and its human homologues AKT1 and AKT2: amplification of AKT1 in a primary human gastric adenocarcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903158909

A retroviral oncogene, akt, encoding a serine-threonine kinase containing an SH2-like region

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903158909

Direct regulation of the Akt proto-oncogene product by phosphatidylinositol-3,4-bisphosphate

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903158909

Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903158909

Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903158909

Regulation of cell death protease caspase-9 by phosphorylation

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425240903158909

Control of apoptosis by Rel/NF-kappaB transcription factors

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425240903158909

Role of the BH3 (Bcl-2 homology 3) domain in the regulation of apoptosis and Bcl-2-related proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903158909

The protooncogene TCL1 is an Akt kinase coactivator

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903158909

Inhibition of Akt kinase activity by a peptide spanning the betaA strand of the proto-oncogene TCL1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903158909

Pseudosubstrate peptides inhibit Akt and induce cell growth inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903158909

Multiple Bcl-2 family members demonstrate selective dimerizations with Bax

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903158909

Structure of Bcl-xL-Bak peptide complex: recognition between regulators of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903158909

Identification of a Bcl-XL binding region within the ATPase domain of Apaf-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903158909

Induction of apoptosis in prostate carcinoma cells by BH3 peptides which inhibit Bak/Bcl-2 interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903158909

Erythrocyte survival is promoted by plasma and suppressed by a Bak-derived BH3 peptide that interacts with membrane-associated Bcl-X(L).

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903158909

Particle assembly incorporating a VP22-BH3 fusion protein, facilitating intracellular delivery, regulated release, and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903158909

Intracellular delivery of Bak BH3 peptide by microbubble-enhanced ultrasound

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903158909

Molecular targeting of drug delivery systems to ovarian cancer by BH3 and LHRH peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903158909

Molecular targeting of BCL2 and BCLXL proteins by synthetic BCL2 homology 3 domain peptide enhances the efficacy of chemotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903158909

Targeting antiapoptotic Bcl-2 family members with cell-permeable BH3 peptides induces apoptosis signaling and death in head and neck squamous cell carcinoma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903158909

Anti-apoptotic Bcl-XL protein in complex with BH3 peptides of pro-apoptotic Bak, Bad, and Bim proteins: comparative molecular dynamics simulations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903158909

Bax interacts with the permeability transition pore to induce permeability transition and cytochrome c release in isolated mitochondria

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425240903158909

Minimal BH3 peptides promote cell death by antagonizing anti-apoptotic proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903158909

Bad is a BH3 domain-containing protein that forms an inactivating dimer with Bcl-XL.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903158909

Dimerization properties of human BAD. Identification of a BH-3 domain and analysis of its binding to mutant BCL-2 and BCL-XL proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903158909

BH3 peptidomimetics potently activate apoptosis and demonstrate single agent efficacy in neuroblastoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903158909

Activation of apoptosis in vivo by a hydrocarbon-stapled BH3 helix

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903158909

A stapled BID BH3 helix directly binds and activates BAX

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903158909

Structural and biochemical basis of apoptotic activation by Smac/DIABLO

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903158909

Structural basis of IAP recognition by Smac/DIABLO

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903158909

Synthetic Smac/DIABLO peptides enhance the effects of chemotherapeutic agents by binding XIAP and cIAP1 in situ

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903158909

A novel polyarginine containing Smac peptide conjugate that mediates cell death in tumor and healthy cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903158909

A small molecule Smac mimic potentiates TRAIL- and TNFalpha-mediated cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903158909

Synthetic Smac peptide enhances the effect of etoposide-induced apoptosis in human glioblastoma cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903158909

Smac/DIABLO enhances the therapeutic potential of chemotherapeutic drugs and irradiation, and sensitizes TRAIL-resistant breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903158909

Cationic cell-penetrating peptides interfere with TNF signalling by induction of TNF receptor internalization

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903158909

A dimeric Smac/diablo peptide directly relieves caspase-3 inhibition by XIAP. Dynamic and cooperative regulation of XIAP by Smac/Diablo

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903158909

A mechanistic insight into SMAC peptide interference with XIAP-Bir2 inhibition of executioner caspases

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903158909

Thermo- and pH-responsive polymers in drug delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903158909

Design of novel bioconjugates for targeted drug delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903158909

Targeted drug delivery via the folate receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903158909

Peptide targeting of tumor lymph vessels

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903158909

Targeting of albumin-embedded paclitaxel nanoparticles to tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903158909

Twenty years of cell-penetrating peptides: from molecular mechanisms to therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903158909

In vivo protein transduction: delivery of a biologically active protein into the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903158909

Cytoplasmic transduction peptide (CTP): New approach for the delivery of biomolecules into cytoplasm in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903158909

Cell-cycle inhibition by independent CDK and PCNA binding domains in p21Cip1

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903158909

10.1517/17425240903158909

21 January 2018

Identifiers

DOI

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21 August 2017

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