Cyclosporin-mediated inhibition of bovine calcineurin by cyclophilins A and B (Q37599093)

21 August 2017

Cyclosporin-mediated inhibition of bovine calcineurin by cyclophilins A and B (English)

1 reference

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12 September 2022

author name string

S. K. Swanson

1

1 reference

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12 September 2022

T. Born

2

1 reference

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12 September 2022

L. D. Zydowsky

3

1 reference

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12 September 2022

H. Cho

4

1 reference

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12 September 2022

H. Y. Chang

5

1 reference

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12 September 2022

C. T. Walsh

6

1 reference

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12 September 2022

F. Rusnak

7

1 reference

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12 September 2022

language of work or name

English

0 references

publication date

1 May 1992

1 reference

PMCID

525566

full work available at URL

21 August 2017

https://europepmc.org/articles/PMC525566

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1315036

https://europepmc.org/articles/PMC525566?pdf=render

12 September 2022

file format

Portable Document Format

online access status

open access

content deliverer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1315036

https://europepmc.org/articles/pmc525566?pdf=render

12 September 2022

file format

Portable Document Format

online access status

open access

1 reference

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https://pnas.org/doi/pdf/10.1073/pnas.89.9.3741

3 December 2023

1 reference

Crossref

DOI

10.1073/PNAS.89.9.3741

https://api.crossref.org/works/10.1073/PNAS.89.9.3741

Proceedings of the National Academy of Sciences of the United States of America

3 December 2023

published in

1 reference

21 August 2017

89

1 reference

21 August 2017

9

1 reference

21 August 2017

3741-3745

1 reference

Activation of calcineurin by limited proteolysis

21 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=525566

Cyclosporin A inhibits T-cell growth factor gene expression at the level of mRNA transcription

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=525566

Cyclophilin: a specific cytosolic binding protein for cyclosporin A

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=525566

Kinetics of the reversible inhibition of enzyme-catalysed reactions by tight-binding inhibitors

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=525566

Characterization of a cDNA clone encoding the calmodulin-binding domain of mouse brain calcineurin

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=525566

Regulatory interactions of calmodulin-binding proteins: phosphorylation of calcineurin by autophosphorylated Ca2+/calmodulin-dependent protein kinase II.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=525566

Peptidyl-prolyl cis-trans isomerase is the cyclosporin A-binding protein cyclophilin

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=525566

Protein phosphatases come of age

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=525566

Cloning of human calcineurin A: evidence for two isozymes and identification of a polyproline structural domain

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=525566

Structural characterization of toxic cyclic peptides from blue-green algae by tandem mass spectrometry

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=525566

Cyclophilin and peptidyl-prolyl cis-trans isomerase are probably identical proteins

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=525566

Cloning, expression, and purification of human cyclophilin in Escherichia coli and assessment of the catalytic role of cysteines by site-directed mutagenesis

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=525566

Cyanobacterial microcystin-LR is a potent and specific inhibitor of protein phosphatases 1 and 2A from both mammals and higher plants

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=525566

Two distinct signal transmission pathways in T lymphocytes are inhibited by complexes formed between an immunophilin and either FK506 or rapamycin

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=525566

Human cyclophilin B: a second cyclophilin gene encodes a peptidyl-prolyl isomerase with a signal sequence

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=525566

Is cyclophilin involved in the immunosuppressive and nephrotoxic mechanism of action of cyclosporin A?

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=525566

Crystal structure of recombinant human T-cell cyclophilin A at 2.5 A resolution

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=525566

Structure of human cyclophilin and its binding site for cyclosporin A determined by X-ray crystallography and NMR spectroscopy

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=525566

The cyclophilin multigene family of peptidyl-prolyl isomerases. Characterization of three separate human isoforms

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=525566

Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=525566

Molecular cloning of a membrane-associated human FK506- and rapamycin-binding protein, FKBP-13

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=525566

Two cytoplasmic candidates for immunophilin action are revealed by affinity for a new cyclophilin: one in the presence and one in the absence of CsA

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=525566

Cyclosporin A specifically inhibits function of nuclear proteins involved in T cell activation

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=525566

Calmodulin-dependent protein phosphatase: a developmental study

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=525566

A kinetic analysis of the effects of inhibitor-1 and inhibitor-2 on the activity of protein phosphatase-1.

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=525566

The association of type 1, type 2A and type 2B phosphatases with the human T lymphocyte plasma membrane

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=525566

Sensitivity to cyclosporin A is mediated by cyclophilin in Neurospora crassa and Saccharomyces cerevisiae.

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=525566

Nuclear association of a T-cell transcription factor blocked by FK-506 and cyclosporin A

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=525566

FK-506 and cyclosporin A inhibit highly similar signal transduction pathways in human T lymphocytes

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=525566

Induction of Interleukin 2 Messenger RNA Inhibited by Cyclosporin A

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=525566

Characterization of bovine brain calmodulindependent protein phosphatase

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=525566

Characterization of phosphotyrosyl-protein phosphatase activity associated with calcineurin.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=525566

Isolation and amino acid sequence of cyclophilin.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=525566

Use of fluorinated tyrosine phosphates to probe the substrate specificity of the low molecular weight phosphatase activity of calcineurin.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=525566

Cyclosporine, FK506, and rapamycin. Some effects on early activation events in serum-free, mitogen-stimulated mouse spleen cells

1 September 2018

1 reference

12 December 2020

Calmodulin purification and fluorescent labeling

1 reference

12 December 2020

Evidence for a second isoform of the catalytic subunit of calmodulin-dependent protein phosphatase (calcineurin A)

1 reference

12 December 2020

Calmodulin, cyclophilin, and cyclosporin A

1 reference

12 December 2020

Cyclosporin A binding to calmodulin: a possible site of action on T lymphocytes

1 reference

12 December 2020

Activation of bovine brain calmodulin-dependent protein phosphatase by limited trypsinization

1 reference

12 December 2020

Cyclosporin A--a chemoprotectant against microcystin-LR toxicity

1 reference

12 December 2020

The immunosuppressant FK506 selectively inhibits expression of early T cell activation genes

1 reference

12 December 2020

Dephosphorylation of cAMP-dependent protein kinase regulatory subunit (type II) by calmodulin-dependent protein phosphatase. Determinants of substrate specificity

1 reference

12 December 2020

Calcium- and calmodulin-sensitive interactions of calcineurin with phospholipids

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.89.9.3741

1 reference

21 August 2017

0 references

1 reference

21 August 2017

1 reference

PMCID

525566