Mesothelin-specific chimeric antigen receptor mRNA-engineered T cells induce anti-tumor activity in solid malignancies. (Q37599478)

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9 March 2020

title

Mesothelin-specific chimeric antigen receptor mRNA-engineered T cells induce anti-tumor activity in solid malignancies (English)

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9 March 2020

1

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12

Carl H June

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9

Bruce L Levine

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9 March 2020

author name string

Andrew R Haas

2

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Marcela V Maus

3

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9 March 2020

Drew A Torigian

4

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9 March 2020

Michael C Soulen

5

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Gabriela Plesa

6

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9 March 2020

Anne Chew

7

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9 March 2020

Yangbing Zhao

8

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9 March 2020

Steven M Albelda

10

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Michael Kalos

11

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9 March 2020

publication date

1 February 2014

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Cancer Immunology Research

9 March 2020

published in

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volume

2

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issue

2

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9 March 2020

page(s)

112-120

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Adoptive T cell transfer for cancer immunotherapy in the era of synthetic biology

9 March 2020

cites work

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Mesothelin-targeted agents in clinical trials and in preclinical development

23 August 2017

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B-cell depletion and remissions of malignancy along with cytokine-associated toxicity in a clinical trial of anti-CD19 chimeric-antigen-receptor-transduced T cells

23 August 2017

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Inducible apoptosis as a safety switch for adoptive cell therapy

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Antitumor activity and long-term fate of chimeric antigen receptor-positive T cells in patients with neuroblastoma

23 August 2017

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T cells with chimeric antigen receptors have potent antitumor effects and can establish memory in patients with advanced leukemia

23 August 2017

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Chimeric antigen receptor-modified T cells in chronic lymphoid leukemia

23 August 2017

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Seromic profiling of ovarian and pancreatic cancer

23 August 2017

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Serologic markers of effective tumor immunity against chronic lymphocytic leukemia include nonmutated B-cell antigens.

23 August 2017

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Control of large, established tumor xenografts with genetically retargeted human T cells containing CD28 and CD137 domains.

23 August 2017

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Protein disulfide isomerases are antibody targets during immune-mediated tumor destruction

23 August 2017

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Do septins have a role in cancer?

23 August 2017

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Expression profiling the human septin gene family

23 August 2017

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Mesothelin-specific CD8(+) T cell responses provide evidence of in vivo cross-priming by antigen-presenting cells in vaccinated pancreatic cancer patients

23 August 2017

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Mesothelin is overexpressed in the vast majority of ductal adenocarcinomas of the pancreas: identification of a new pancreatic cancer marker by serial analysis of gene expression (SAGE).

23 August 2017

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Identification of differentially expressed genes associated with HER-2/neu overexpression in human breast cancer cells

23 August 2017

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Molecular cloning of mesothelin, a differentiation antigen present on mesothelium, mesotheliomas, and ovarian cancers

23 August 2017

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Anti-PD-1 antibody therapy potently enhances the eradication of established tumors by gene-modified T cells

23 August 2017

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Immunologic biomarkers as correlates of clinical response to cancer immunotherapy

6 September 2017

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Multiple injections of electroporated autologous T cells expressing a chimeric antigen receptor mediate regression of human disseminated tumor

6 September 2017

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6 September 2017

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14 September 2017

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Major Cancer Regressions in Mesothelioma After Treatment with an Anti-Mesothelin Immunotoxin and Immune Suppression

25 June 2018

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Humoral immune response to mesothelin in mesothelioma and ovarian cancer patients

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Treatment of metastatic renal cell carcinoma with autologous T-lymphocytes genetically retargeted against carbonic anhydrase IX: first clinical experience

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12 December 2020

Phase I study of SS1P, a recombinant anti-mesothelin immunotoxin given as a bolus I.V. infusion to patients with mesothelin-expressing mesothelioma, ovarian, and pancreatic cancers

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12 December 2020

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Identifiers

DOI

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9 March 2020

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9 March 2020

PubMed publication ID

24579088

1 reference