Are stem cells a cure for diabetes? (Q37609481)

21 August 2017

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title

Are stem cells a cure for diabetes? (English)

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21 August 2017

Michael D McCall

1

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21 August 2017

Christian Toso

series ordinal

2

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21 August 2017

Emmanuel E Baetge

series ordinal

3

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21 August 2017

A M James Shapiro

series ordinal

4

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21 August 2017

language of work or name

English

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publication date

12 October 2009

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21 August 2017

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21 August 2017

volume

118

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21 August 2017

issue

2

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21 August 2017

page(s)

87-97

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The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. The Diabetes Control and Complications Trial Research Group

21 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1042%2FCS20090072

Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). UK Prospective Diabetes Study (UKPDS) Group

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20090072

Pancreas transplant outcomes for United States (US) and non-US cases as reported to the United Network for Organ Sharing (UNOS) and the International Pancreas Transplant Registry (IPTR) as of June 2004.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20090072

Automated islet isolation from human pancreas

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20090072

Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive regimen

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20090072

International trial of the Edmonton protocol for islet transplantation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20090072

Five-year follow-up after clinical islet transplantation

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20090072

Successful islet transplantation: continued insulin reserve provides long-term glycemic control

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20090072

Assessment of the severity of hypoglycemia and glycemic lability in type 1 diabetic subjects undergoing islet transplantation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20090072

Estimating the number of potential organ donors in the United States

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20090072

Follow-up study of the first successful living donor islet transplantation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20090072

Insulin independence after living-donor distal pancreatectomy and islet allotransplantation

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20090072

Reversal of diabetes in pancreatectomized pigs after transplantation of neonatal porcine islets

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20090072

Long-term survival of neonatal porcine islets in nonhuman primates by targeting costimulation pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20090072

Cytological demonstration of the clonal nature of spleen colonies derived from transplanted mouse marrow cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20090072

Establishment in culture of pluripotential cells from mouse embryos

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20090072

Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20090072

Embryonic stem cell lines derived from human blastocysts

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20090072

Isolation of amniotic stem cell lines with potential for therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20090072

Generation of pluripotent stem cells from adult human testis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20090072

The role of stem cells in the post-MI patient

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20090072

A single course of anti-CD3 monoclonal antibody hOKT3gamma1(Ala-Ala) results in improvement in C-peptide responses and clinical parameters for at least 2 years after onset of type 1 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20090072

Anti-CD3 monoclonal antibody in new-onset type 1 diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20090072

Rational development of LEA29Y (belatacept), a high-affinity variant of CTLA4-Ig with potent immunosuppressive properties.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20090072

Costimulation blockade with belatacept in renal transplantation

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20090072

In vitro cultivation of human islets from expanded ductal tissue

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20090072

Characterization of endocrine progenitor cells and critical factors for their differentiation in human adult pancreatic cell culture

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20090072

Clonal identification of multipotent precursors from adult mouse pancreas that generate neural and pancreatic lineages

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20090072

Multipotential nestin-positive stem cells isolated from adult pancreatic islets differentiate ex vivo into pancreatic endocrine, exocrine, and hepatic phenotypes

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20090072

Multipotential nestin and Isl-1 positive mesenchymal stem cells isolated from human pancreatic islets.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20090072

Adult pancreatic beta-cells are formed by self-duplication rather than stem-cell differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20090072

Beta cells can be generated from endogenous progenitors in injured adult mouse pancreas

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20090072

Notch signalling controls pancreatic cell differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20090072

In vitro generation of insulin-producing beta cells from adult exocrine pancreatic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20090072

In vivo reprogramming of adult pancreatic exocrine cells to beta-cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20090072

Multi-organ, multi-lineage engraftment by a single bone marrow-derived stem cell

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20090072

From marrow to brain: expression of neuronal phenotypes in adult mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20090072

Pluripotency of mesenchymal stem cells derived from adult marrow

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20090072

Purified hematopoietic stem cells can differentiate into hepatocytes in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20090072

In vivo derivation of glucose-competent pancreatic endocrine cells from bone marrow without evidence of cell fusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20090072

Bone marrow-derived stem cells initiate pancreatic regeneration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20090072

Little evidence of transdifferentiation of bone marrow-derived cells into pancreatic beta cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20090072

Islet Regeneration During the Reversal of Autoimmune Diabetes in NOD Mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20090072

Islet recovery and reversal of murine type 1 diabetes in the absence of any infused spleen cell contribution

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20090072

Reversal of diabetes in non-obese diabetic mice without spleen cell-derived beta cell regeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20090072

Immunological reversal of autoimmune diabetes without hematopoietic replacement of beta cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20090072

Human cord blood--derived cells generate insulin-producing cells in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20090072

Differentiation of embryonic stem cells to insulin-secreting structures similar to pancreatic islets.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20090072

Directed engineering of umbilical cord blood stem cells to produce C-peptide and insulin

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20090072

Autologous umbilical cord blood infusion for type 1 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20090072

C-peptide levels and insulin independence following autologous nonmyeloablative hematopoietic stem cell transplantation in newly diagnosed type 1 diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20090072

Combined treatment of intrapancreatic autologous bone marrow stem cells and hyperbaric oxygen in type 2 diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20090072

Hepatic oval cells express the hematopoietic stem cell marker Thy-1 in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20090072

Pancreatic and duodenal homeobox gene 1 induces expression of insulin genes in liver and ameliorates streptozotocin-induced hyperglycemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20090072

In vitro trans-differentiation of adult hepatic stem cells into pancreatic endocrine hormone-producing cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20090072

Functional, persistent, and extended liver to pancreas transdifferentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20090072

NeuroD-betacellulin gene therapy induces islet neogenesis in the liver and reverses diabetes in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20090072

Reversal of hyperglycemia in mice by using human expandable insulin-producing cells differentiated from fetal liver progenitor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20090072

High glucose is necessary for complete maturation of Pdx1-VP16-expressing hepatic cells into functional insulin-producing cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20090072

PDX-1/VP16 fusion protein, together with NeuroD or Ngn3, markedly induces insulin gene transcription and ameliorates glucose tolerance

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20090072

A crucial role of MafA as a novel therapeutic target for diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20090072

Streptozotocin-induced diabetes can be reversed by hepatic oval cell activation through hepatic transdifferentiation and pancreatic islet regeneration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20090072

Cell-replacement therapy for diabetes: Generating functional insulin-producing tissue from adult human liver cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20090072

PDX-1 induces differentiation of intestinal epithelioid IEC-6 into insulin-producing cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20090072

Combined expression of pancreatic duodenal homeobox 1 and islet factor 1 induces immature enterocytes to produce insulin

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20090072

Glucagon-like peptide 1 (1-37) converts intestinal epithelial cells into insulin-producing cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20090072

Human adipose tissue-derived mesenchymal stem cells differentiate into insulin, somatostatin, and glucagon expressing cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20090072

Insulin-secreting cells derived from embryonic stem cells normalize glycemia in streptozotocin-induced diabetic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20090072

Growth inhibitors promote differentiation of insulin-producing tissue from embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20090072

Pancreatic precursors and differentiated islet cell types from murine embryonic stem cells: an in vitro model to study islet differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20090072

Embryonic stem cells differentiate into insulin-producing cells without selection of nestin-expressing cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20090072

Expression of Pax4 in embryonic stem cells promotes differentiation of nestin-positive progenitor and insulin-producing cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20090072

Regulated expression of pdx-1 promotes in vitro differentiation of insulin-producing cells from embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20090072

Insulin production by human embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20090072

Differentiation of human embryonic stem cells into insulin-producing clusters

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20090072

Differentiation of insulin-producing cells from human neural progenitor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20090072

Artifactual insulin release from differentiated embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20090072

Insulin expressing cells from differentiated embryonic stem cells are not beta cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20090072

Gastrulation in the mouse embryo: ultrastructural and molecular aspects of germ layer morphogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20090072

Vertebrate endoderm development

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20090072

Gene expression cascades in pancreatic development

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20090072

Development of definitive endoderm from embryonic stem cells in culture

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20090072

Efficient differentiation of human embryonic stem cells to definitive endoderm

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20090072

Production of pancreatic hormone-expressing endocrine cells from human embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20090072

Pancreatic endoderm derived from human embryonic stem cells generates glucose-responsive insulin-secreting cells in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20090072

Blood glucose normalization upon transplantation of human embryonic pancreas into beta-cell-deficient SCID mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20090072

Normal relationship of beta- and non-beta-cells not needed for successful islet transplantation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20090072

Islet growth and development in the adult

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20090072

Viable offspring derived from fetal and adult mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20090072

Induced pluripotent stem cell lines derived from human somatic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20090072

Time to reconsider stem cell ethics--the importance of induced pluripotent cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20090072

Recruitment of Bone Marrow-Derived Endothelial Cells to Sites of Pancreatic -Cell Injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20090072

Quality of Life After Islet Transplant: Impact of the Number of Islet Infusions and Metabolic Outcome

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20090072

21 January 2018

Identifiers

DOI

10.1042/CS20090072

1 reference

21 August 2017

1 reference