In silico methods for predicting T-cell epitopes: Dr Jekyll or Mr Hyde? (Q37610312)

21 August 2017

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title

In silico methods for predicting T-cell epitopes: Dr Jekyll or Mr Hyde? (English)

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21 August 2017

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Uthaman Gowthaman

1

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21 August 2017

Javed N Agrewala

series ordinal

2

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21 August 2017

publication date

1 October 2009

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Expert Review of Proteomics

21 August 2017

published in

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21 August 2017

volume

6

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21 August 2017

issue

5

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21 August 2017

page(s)

527-537

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The contribution of immunology to the rational design of novel antibacterial vaccines

21 August 2017

cites work

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Dominance and crypticity of T cell antigenic determinants

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Restriction of in vitro T cell-mediated cytotoxicity in lymphocytic choriomeningitis within a syngeneic or semiallogeneic system.

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Harnessing bioinformatics to discover new vaccines

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Specificity pockets for the side chains of peptide antigens in HLA-Aw68

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Enhancement to the RANKPEP resource for the prediction of peptide binding to MHC molecules using profiles.

21 January 2018

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Methods and protocols for prediction of immunogenic epitopes

21 January 2018

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Interactions between immunogenic peptides and MHC proteins

21 January 2018

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How TCRs bind MHCs, peptides, and coreceptors

21 January 2018

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Assessing the accuracy of prediction algorithms for classification: an overview

21 January 2018

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Towards a consensus on datasets and evaluation metrics for developing B-cell epitope prediction tools

21 January 2018

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Prediction of major histocompatibility complex binding regions of protein antigens by sequence pattern analysis

21 January 2018

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SYFPEITHI: database for MHC ligands and peptide motifs

21 January 2018

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Prominent role of secondary anchor residues in peptide binding to HLA-A2.1 molecules

21 January 2018

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Improved prediction of MHC class I and class II epitopes using a novel Gibbs sampling approach

21 January 2018

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SVMHC: a server for prediction of MHC-binding peptides

21 January 2018

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Prediction of MHC class II-binding peptides using an evolutionary algorithm and artificial neural network

21 January 2018

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Predicting peptides that bind to MHC molecules using supervised learning of hidden Markov models.

21 January 2018

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A consensus epitope prediction approach identifies the breadth of murine T(CD8+)-cell responses to vaccinia virus

21 January 2018

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Computational prediction and identification of dengue virus-specific CD4(+) T-cell epitopes

21 January 2018

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Identification of novel consensus CD4 T-cell epitopes from clade B HIV-1 whole genome that are frequently recognized by HIV-1 infected patients.

21 January 2018

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Computational prediction and identification of Epstein-Barr virus latent membrane protein 2A antigen-specific CD8+ T-cell epitopes

21 January 2018

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Identification of a MHC class-II restricted epitope in carcinoembryonic antigen

21 January 2018

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Identification of new cytotoxic T-lymphocyte epitopes from cancer testis antigen HCA587.

21 January 2018

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Identification of a highly immunogenic HLA-A*01-binding T cell epitope of WT1.

21 January 2018

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Identification of a new HLA-A*0201-restricted cryptic epitope from CYP1B1.

21 January 2018

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Clinical validation of the "in silico" prediction of immunogenicity of a human recombinant therapeutic protein.

21 January 2018

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CD8+ T cells specific for a potential HLA-A*0201 epitope from Chlamydophila pneumoniae are present in the PBMCs from infected patients

21 January 2018

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Human CD8(+) T cell responses against five newly identified respiratory syncytial virus-derived epitopes

21 January 2018

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Recognition of HLA class I-restricted beta-cell epitopes in type 1 diabetes.

21 January 2018

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Identification of Novel HLA-A*0201-restricted epitopes in recent-onset type 1 diabetic subjects and antibody-positive relatives

21 January 2018

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Human CD4+ T cell epitopes from vaccinia virus induced by vaccination or infection

21 January 2018

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Large-scale validation of methods for cytotoxic T-lymphocyte epitope prediction

21 January 2018

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Peptide binding motif predictive algorithms correspond with experimental binding of leukemia vaccine candidate peptides to HLA-A*0201 molecules

21 January 2018

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Searching for borrelial T cell epitopes associated with antibiotic-refractory Lyme arthritis

21 January 2018

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Validation of in silico prediction by in vitro immunoserological results of fine epitope mapping on citrate synthase specific autoantibodies

21 January 2018

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Poor correspondence between predicted and experimental binding of peptides to class I MHC molecules

21 January 2018

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Identification of an HLA-DR-restricted peptide epitope with a promiscuous binding pattern derived from the cancer testis antigen HOM-MEL-40/SSX2.

21 January 2018

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Uneven distribution of MHC class II epitopes within the influenza virus

21 January 2018

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Tissue-specific regulation of CD8+ T-lymphocyte immunodominance in respiratory syncytial virus infection

21 January 2018

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Strength in numbers: achieving greater accuracy in MHC-I binding prediction by combining the results from multiple prediction tools

21 January 2018

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Identification of Plasmodium falciparum antigens by antigenic analysis of genomic and proteomic data

21 January 2018

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Evaluation of MHC-II peptide binding prediction servers: applications for vaccine research

21 January 2018

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T cell receptor-MHC interactions up close

21 January 2018

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Crystal structure of the human class II MHC protein HLA-DR1 complexed with an influenza virus peptide

21 January 2018

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On Evaluating MHC-II Binding Peptide Prediction Methods

21 January 2018

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The wide diversity and complexity of peptides bound to class II MHC molecules

21 January 2018

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Evaluation of MHC class I peptide binding prediction servers: applications for vaccine research

21 January 2018

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T-cell epitope prediction: rescaling can mask biological variation between MHC molecules

21 January 2018

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Influence of HLA-DR on the phenotype of CD4+ T lymphocytes specific for an epitope of the 16-kDa alpha-crystallin antigen of Mycobacterium tuberculosis

21 January 2018

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Are bacterial vaccine antigens T-cell epitope depleted?

21 January 2018

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In SilicoTools for Predicting Peptides Binding to HLA-Class II Molecules: More Confusion than Conclusion

21 January 2018

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From genome to vaccines for leishmaniasis: Screening 100 novel vaccine candidates against murine Leishmania major infection

21 January 2018

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Generation of tissue-specific and promiscuous HLA ligand databases using DNA microarrays and virtual HLA class II matrices

21 January 2018

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Binding of immunogenic peptides to Ia histocompatibility molecules

21 January 2018

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21 January 2018

Identifiers

DOI

10.1586/EPR.09.71

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21 August 2017

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