Apolipoprotein E4 in macrophages enhances atherogenesis in a low density lipoprotein receptor-dependent manner (Q37612769)

21 August 2017

Apolipoprotein E4 in macrophages enhances atherogenesis in a low density lipoprotein receptor-dependent manner (English)

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21 August 2017

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Michael Altenburg

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21 August 2017

Lance Johnson

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2

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21 August 2017

Jennifer Wilder

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3

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21 August 2017

Nobuyo Maeda

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4

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21 August 2017

language of work or name

English

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publication date

18 January 2007

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Journal of Biological Chemistry

21 August 2017

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21 August 2017

282

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21 August 2017

11

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21 August 2017

7817-7824

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describes a project that uses

21 August 2017

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5278600/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Apolipoprotein E (apoE) isoforms differentially induce nitric oxide production in endothelial cells

1 reference

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Apolipoprotein E: far more than a lipid transport protein

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5278600

Control of cellular cholesterol efflux by the nuclear oxysterol receptor LXR alpha

23 August 2017

1 reference

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Apolipoprotein E and atherosclerosis

23 August 2017

1 reference

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Sterol-dependent transactivation of the ABC1 promoter by the liver X receptor/retinoid X receptor

23 August 2017

1 reference

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Apo E structure determines VLDL clearance and atherosclerosis risk in mice.

23 August 2017

1 reference

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Atherosclerosis — An Inflammatory Disease

23 August 2017

1 reference

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Type III hyperlipoproteinemia and spontaneous atherosclerosis in mice resulting from gene replacement of mouse Apoe with human Apoe*2

23 August 2017

1 reference

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Phenotype-dependent differences in apolipoprotein E metabolism and in cholesterol homeostasis in human monocyte-derived macrophages

23 August 2017

1 reference

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Inhibition of diet-induced atheroma formation in transgenic mice expressing apolipoprotein E in the arterial wall

23 August 2017

1 reference

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Foam cell-forming J774 macrophages have markedly elevated acyl coenzyme A:cholesterol acyl transferase activity compared with mouse peritoneal macrophages in the presence of low density lipoprotein (LDL) despite similar LDL receptor activity

23 August 2017

1 reference

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Apolipoprotein E: cholesterol transport protein with expanding role in cell biology

23 August 2017

1 reference

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Uptake of cholesterol-rich remnant lipoproteins by human monocyte-derived macrophages is mediated by low density lipoprotein receptors

23 August 2017

1 reference

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The role of apolipoprotein E genetic variants in lipoprotein disorders

23 August 2017

1 reference

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Spontaneous hypercholesterolemia and arterial lesions in mice lacking apolipoprotein E

23 August 2017

1 reference

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Degradation of cationized low density lipoprotein and regulation of cholesterol metabolism in homozygous familial hypercholesterolemia fibroblasts

23 August 2017

1 reference

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Impaired recycling of apolipoprotein E4 is associated with intracellular cholesterol accumulation.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5278600

Secreted apolipoprotein E reduces macrophage-mediated LDL oxidation in an isoform-dependent way.

14 September 2017

1 reference

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Isoform-dependent cholesterol efflux from macrophages by apolipoprotein E is modulated by cell surface proteoglycans.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5278600

Apolipoprotein E inhibition of vascular smooth muscle cell proliferation but not the inhibition of migration is mediated through activation of inducible nitric oxide synthase

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5278600

Apolipoprotein E allele-specific antioxidant activity and effects on cytotoxicity by oxidative insults and beta-amyloid peptides

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5278600

Apolipoprotein (apo) E genotype and apoE concentration determine binding of normal very low density lipoproteins to HepG2 cell surface receptors.

28 September 2017

1 reference

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Regulation of macrophage apoE secretion and sterol efflux by the LDL receptor

28 September 2017

1 reference

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The recycling of apolipoprotein E in macrophages: influence of HDL and apolipoprotein A-I.

25 June 2018

1 reference

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Defective VLDL metabolism and severe atherosclerosis in mice expressing human apolipoprotein E isoforms but lacking the LDL receptor

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5278600

Harmful effects of increased LDLR expression in mice with human APOE*4 but not APOE*3.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5278600

The recycling of apolipoprotein E in primary cultures of mouse hepatocytes. Evidence for a physiologic connection to high density lipoprotein metabolism

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5278600

Distinct apolipoprotein E isoform preference for inhibition of smooth muscle cell migration and proliferation

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5278600

Doubling expression of the low density lipoprotein receptor by truncation of the 3'-untranslated region sequence ameliorates type iii hyperlipoproteinemia in mice expressing the human apoe2 isoform

1 September 2018

1 reference

12 December 2020

Apolipoprotein E polymorphism and atherosclerosis

1 reference

12 December 2020

Effect of bone marrow transplantation on lipoprotein metabolism and atherosclerosis in LDL receptor-knockout mice

1 reference

12 December 2020

Rapid fluorometric assay of LDL receptor activity by DiI-labeled LDL

1 reference

12 December 2020

Low density lipoprotein receptor of macrophages facilitates atherosclerotic lesion formation in C57Bl/6 mice

1 reference

12 December 2020

A direct role for the macrophage low density lipoprotein receptor in atherosclerotic lesion formation

1 reference

12 December 2020

Targeted replacement of the mouse apolipoprotein E gene with the common human APOE3 allele enhances diet-induced hypercholesterolemia and atherosclerosis

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M610712200

1 reference

21 August 2017

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21 August 2017

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