ERK and cell death: cadmium toxicity, sustained ERK activation and cell death (Q37618287)

21 August 2017

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title

ERK and cell death: cadmium toxicity, sustained ERK activation and cell death (English)

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21 August 2017

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Patrick Martin

1

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PubMed ID

19843171

21 August 2017

Philippe Pognonec

series ordinal

2

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PubMed ID

19843171

21 August 2017

language of work or name

English

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publication date

16 October 2009

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21 August 2017

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21 August 2017

277

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21 August 2017

1

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21 August 2017

39-46

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The regulation of extracellular signal-regulated kinase (ERK) in mammalian cells

21 August 2017

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07369.X

Major substrate for growth factor-activated protein-tyrosine kinases is a low-abundance protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07369.X

ERKs: a family of protein-serine/threonine kinases that are activated and tyrosine phosphorylated in response to insulin and NGF

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07369.X

An insulin-stimulated protein kinase similar to yeast kinases involved in cell cycle control

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07369.X

Cell type-specific modulation of cell growth by transforming growth factor beta 1 does not correlate with mitogen-activated protein kinase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07369.X

Mitogen-activated protein kinases p42mapk and p44mapk are required for fibroblast proliferation

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07369.X

Total ERK1/2 activity regulates cell proliferation

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07369.X

Single and combined silencing of ERK1 and ERK2 reveals their positive contribution to growth signaling depending on their expression levels

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07369.X

MAPK3/1 (ERK1/2) in ovarian granulosa cells are essential for female fertility.

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07369.X

ERK and p38 MAPK-activated protein kinases: a family of protein kinases with diverse biological functions

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07369.X

Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07369.X

The duration, magnitude and compartmentalization of ERK MAP kinase activity: mechanisms for providing signaling specificity.

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07369.X

Coordinating ERK/MAPK signalling through scaffolds and inhibitors

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07369.X

Involvement of the extracellular signal-regulated protein kinase (ERK) pathway in the induction of apoptosis by cadmium chloride in CCRF-CEM cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07369.X

Hwanggunchungyitang prevents cadmium-induced ototoxicity through suppression of the activation of caspase-9 and extracellular signal-related kinase in auditory HEI-OC1 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07369.X

MAPK and mTOR pathways are involved in cadmium-induced neuronal apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07369.X

Extracellular signal-regulated kinase-signaling-dependent G2/M arrest and cell death in murine macrophages by cadmium

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07369.X

Long-term extracellular signal-related kinase activation following cadmium intoxication is negatively regulated by a protein kinase C-dependent pathway affecting cadmium transport

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07369.X

Roles of JNK, p38 and ERK mitogen-activated protein kinases in the growth inhibition and apoptosis induced by cadmium

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07369.X

Opposite roles of ERK and p38 mitogen-activated protein kinases in cadmium-induced genotoxicity and mitotic arrest.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07369.X

Role of mitogen activated protein kinases and protein kinase C in cadmium-induced apoptosis of primary epithelial lung cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07369.X

Cadmium induces apoptotic cell death through p38 MAPK in brain microvessel endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07369.X

Cadmium-induced apoptosis in lymphoblastoid cell line: involvement of caspase-dependent and -independent pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07369.X

Stimulation of p38 mitogen-activated protein kinase is an early regulatory event for the cadmium-induced apoptosis in human promonocytic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07369.X

Regulation of MAP kinases by MAP kinase phosphatases.

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07369.X

Oxidative mechanisms in the toxicity of metal ions

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07369.X

Apoptosis and necrosis: two distinct events induced by cadmium in cortical neurons in culture.

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07369.X

Cadmium-induced apoptosis in murine macrophages is antagonized by antioxidants and caspase inhibitors

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07369.X

Zn2+-induced ERK activation mediated by reactive oxygen species causes cell death in differentiated PC12 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07369.X

Oxidative stress activates extracellular signal-regulated kinases through Src and Ras in cultured cardiac myocytes of neonatal rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07369.X

Mitogen-activated protein kinase pathways in redox signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07369.X

Loss of MKP3 mediated by oxidative stress enhances tumorigenicity and chemoresistance of ovarian cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07369.X

Reactive oxygen species promote TNFalpha-induced death and sustained JNK activation by inhibiting MAP kinase phosphatases

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07369.X

Reversible oxidation of ERK-directed protein phosphatases drives oxidative toxicity in neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07369.X

Endoplasmic reticulum stress and alteration in calcium homeostasis are involved in cadmium-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07369.X

Inhibition of cadmium-induced oxidative injury in rat primary astrocytes by the addition of antioxidants and the reduction of intracellular calcium.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07369.X

Cadmium-induced autophagy and apoptosis are mediated by a calcium signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07369.X

Covalent inhibition revealed by the crystal structure of the caspase-8/p35 complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07369.X

Cadmium activates the mitogen-activated protein kinase (MAPK) pathway via induction of reactive oxygen species and inhibition of protein phosphatases 2A and 5

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07369.X

Cadmium induces reactive oxygen species generation and lipid peroxidation in cortical neurons in culture

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07369.X

Prolonged activation of ERK1,2 induces FADD-independent caspase 8 activation and cell death.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07369.X

Targeting the protein kinase C family: are we there yet?

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07369.X

TPA-induced activation of MAP kinase

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07369.X

The protein kinase C inhibitors Ro 318220 and GF 109203X are equally potent inhibitors of MAPKAP kinase-1beta (Rsk-2) and p70 S6 kinase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07369.X

Mechanisms regulating the cadmium-mediated suppression of Sp1 transcription factor activity in alveolar epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07369.X

Individual PKC-phosphorylation sites in organic cation transporter 1 determine substrate selectivity and transport regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07369.X

Classical isoforms of PKC as regulators of CAT-1 transporter activity in pulmonary artery endothelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07369.X

Two major branches of anti-cadmium defense in the mouse: MTF-1/metallothioneins and glutathione

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07369.X

Cadmium and cellular signaling cascades: to be or not to be?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07369.X

10.1111/J.1742-4658.2009.07369.X

21 January 2018

Identifiers

DOI

1 reference

21 August 2017

1 reference

PubMed ID

19843171