Chapter 8: Clusterin: A multifacet protein at the crossroad of inflammation and autoimmunity (Q37624993)

21 August 2017

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title

Chapter 8: Clusterin: A multifacet protein at the crossroad of inflammation and autoimmunity (English)

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21 August 2017

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Géraldine Falgarone

1

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PubMed ID

19878776

21 August 2017

Gilles Chiocchia

series ordinal

2

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21 August 2017

1 January 2009

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Advances in Cancer Research

21 August 2017

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21 August 2017

104

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21 August 2017

139-170

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Surface phenotype and antigenic specificity of human interleukin 17-producing T helper memory cells

21 August 2017

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https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2904008-1

7 January 2021

Protein SIC, a novel extracellular protein of Streptococcus pyogenes interfering with complement function

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https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2904008-1

7 January 2021

Apolipoprotein J expression at fluid-tissue interfaces: potential role in barrier cytoprotection

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https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2904008-1

7 January 2021

NF-kappa B regulation by I kappa B kinase-2 in rheumatoid arthritis synoviocytes

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https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2904008-1

7 January 2021

Expression and regulation of inducible IkappaB kinase (IKK-i) in human fibroblast-like synoviocytes

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https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2904008-1

7 January 2021

Predominant selection of T cells specific for the glycosylated collagen type II epitope (263-270) in humanized transgenic mice and in rheumatoid arthritis

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https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2904008-1

7 January 2021

The terminal complement complex is generated in chronic leg ulcers in the absence of protectin (CD59)

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https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2904008-1

7 January 2021

Nuclear factor-kappaB: a pivotal transcription factor in chronic inflammatory diseases

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https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2904008-1

7 January 2021

Dendritic cell maturation results in pronounced changes in glycan expression affecting recognition by siglecs and galectins

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https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2904008-1

7 January 2021

Shifting the imbalance from Th1/Th2 to Th17/treg: the changing rheumatoid arthritis paradigm

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https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2904008-1

7 January 2021

Defining therapeutic targets by using adenovirus: blocking NF-kappaB inhibits both inflammatory and destructive mechanisms in rheumatoid synovium but spares anti-inflammatory mediators

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https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2904008-1

7 January 2021

Activating and inhibitory IgG Fc receptors on human DCs mediate opposing functions

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https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2904008-1

7 January 2021

Effect of chronic ethanol consumption on the expression of complement components and acute-phase proteins in liver.

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https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2904008-1

7 January 2021

Clusterin overexpression in rat pancreas during the acute phase of pancreatitis and pancreatic development

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https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2904008-1

7 January 2021

Immunohistochemical and morphometric studies of the fetal pancreas in diabetic pregnant rats. Effects of insulin administration.

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https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2904008-1

7 January 2021

Isolation and functional characterization of regulatory CD25brightCD4+ T cells from the target organ of patients with rheumatoid arthritis

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https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2904008-1

7 January 2021

Presence of plasma complement regulatory proteins clusterin (Apo J) and vitronectin (S40) on circulating immune complexes (CIC)

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https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2904008-1

7 January 2021

Distinct regulation of interleukin-17 in human T helper lymphocytes

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https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2904008-1

7 January 2021

Duration of chronic inflammation alters gene expression in muscle from untreated girls with juvenile dermatomyositis

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https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2904008-1

7 January 2021

Clusterin may be involved in rat liver allograft tolerance

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https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2904008-1

7 January 2021

T cell regulation of collagen-induced arthritis in mice. III. Is T cell vaccination a valuable therapy?

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https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2904008-1

7 January 2021

A serum protein SP40,40 modulates the formation of membrane attack complex of complement on erythrocytes

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https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2904008-1

7 January 2021

Critical regulation of early Th17 cell differentiation by interleukin-1 signaling

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https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2904008-1

7 January 2021

Clusterin expression in adult human normal and osteoarthritic articular cartilage

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2904008-1

7 January 2021

Immunisation against heterologous type II collagen induces arthritis in mice

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https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2904008-1

7 January 2021

Bcl-2 facilitates recovery from DNA damage after oxidative stress

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https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2904008-1

7 January 2021

[What place for DNA microarray in inflammatory diseases?].

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https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2904008-1

7 January 2021

DNA microarray allows molecular profiling of rheumatoid arthritis and identification of pathophysiological targets.

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https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2904008-1

7 January 2021

Characterization and functional consequences of underexpression of clusterin in rheumatoid arthritis.

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https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2904008-1

7 January 2021

Selective blockade of the inhibitory Fcgamma receptor (FcgammaRIIB) in human dendritic cells and monocytes induces a type I interferon response program

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https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2904008-1

7 January 2021

Phytoestrogens and carcinogenesis-differential effects of genistein in experimental models of normal and malignant rat endometrium

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https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2904008-1

7 January 2021

Post-translational protein modifications in antigen recognition and autoimmunity

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https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2904008-1

7 January 2021

Compromised function of regulatory T cells in rheumatoid arthritis and reversal by anti-TNFalpha therapy

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https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2904008-1

7 January 2021

Role of cytokines in rheumatoid arthritis

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https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2904008-1

7 January 2021

C-type lectin receptors on dendritic cells and Langerhans cells

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https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2904008-1

7 January 2021

Interleukin 6 promotes murine lupus in NZB/NZW F1 mice

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https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2904008-1

7 January 2021

How important are T cells in chronic rheumatoid synovitis?

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https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2904008-1

7 January 2021

How important are T cells in chronic rheumatoid synovitis?: II. T cell-independent mechanisms from beginning to end.

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https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2904008-1

7 January 2021

Membrane attack complex (MAC) deposits in skin are not always accompanied by S-protein and clusterin

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https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2904008-1

7 January 2021

Autoimmune inflammation from the Th17 perspective

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https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2904008-1

7 January 2021

Clusterin protects renal tubular epithelial cells from gentamicin-mediated cytotoxicity

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https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2904008-1

7 January 2021

Thymic function and peripheral T-cell homeostasis in rheumatoid arthritis

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https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2904008-1

7 January 2021

Dendritic cells and interferon-mediated autoimmunity

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https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2904008-1

7 January 2021

Antigen presentation and T cell stimulation by dendritic cells

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https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2904008-1

7 January 2021

Endotoxin and cytokines increase hepatic messenger RNA levels and serum concentrations of apolipoprotein J (clusterin) in Syrian hamsters

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https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2904008-1

7 January 2021

Immune complex-induced enhancement of bacterial antigen presentation requires Fcgamma receptor III expression on dendritic cells.

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https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2904008-1

7 January 2021

Microarray gene expression profiling of osteoarthritic bone suggests altered bone remodelling, WNT and transforming growth factor-beta/bone morphogenic protein signalling

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https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2904008-1

7 January 2021

The inhibition of angiogenesis by antisense oligonucleotides to clusterin

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https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2904008-1

7 January 2021

No evidence of major effects in several Toll-like receptor gene polymorphisms in rheumatoid arthritis

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https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2904008-1

7 January 2021

Danger - pathogen on the premises! Immunological tolerance

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https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2904008-1

7 January 2021

Cell death induced by zinc and cadmium is mediated by clusterin in cultured mouse seminiferous tubules

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https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2904008-1

7 January 2021

Expression of clusterin in the superficial zone of bovine articular cartilage

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2904008-1

7 January 2021

Enrichment of differentiated CD45RBdim,CD27- memory T cells in the peripheral blood, synovial fluid, and synovial tissue of patients with rheumatoid arthritis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2904008-1

7 January 2021

Antibodies against citrullinated proteins enhance tissue injury in experimental autoimmune arthritis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2904008-1

7 January 2021

Identification and initial characterization of 5000 expressed sequenced tags (ESTs) each from adult human normal and osteoarthritic cartilage cDNA libraries

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2904008-1

7 January 2021

Immune complexes inhibit differentiation, maturation, and function of human monocyte-derived dendritic cells.

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https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2904008-1

7 January 2021

Synthesis and functional analyses of nuclear clusterin, a cell death protein

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https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2904008-1

7 January 2021

Development of resistance to chemotherapeutic drugs in human osteosarcoma cell lines largely depends on up-regulation of Clusterin/Apolipoprotein J.

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https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2904008-1

7 January 2021

Cells of the synovium in rheumatoid arthritis. Dendritic cells.

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https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2904008-1

7 January 2021

NF-kappa B in rheumatoid arthritis: a pivotal regulator of inflammation, hyperplasia, and tissue destruction

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https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2904008-1

7 January 2021

Vanadium-induced apoptosis of HaCaT cells is mediated by c-fos and involves nuclear accumulation of clusterin.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2904008-1

7 January 2021

The major synovial targets of the rheumatoid arthritis-specific antifilaggrin autoantibodies are deiminated forms of the alpha- and beta-chains of fibrin

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2904008-1

7 January 2021

Clusterin, an abundant serum factor, is a possible negative regulator of MT6-MMP/MMP-25 produced by neutrophils.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2904008-1

7 January 2021

How antibodies to a ubiquitous cytoplasmic enzyme may provoke joint-specific autoimmune disease

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https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2904008-1

7 January 2021

Tolerance, danger, and the extended family

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https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2904008-1

7 January 2021

Apolipoprotein J/clusterin limits the severity of murine autoimmune myocarditis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2904008-1

7 January 2021

Application of proteomics in the discovery of candidate protein biomarkers in a diabetes autoantibody standardization program sample subset.

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https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2904008-1

7 January 2021

NF-kappaB activation provides the potential link between inflammation and hyperplasia in the arthritic joint

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2904008-1

7 January 2021

Clusterin isoforms differentially affect growth and motility of prostate cells: possible implications in prostate tumorigenesis.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2904008-1

7 January 2021

SP-40,40, a newly identified normal human serum protein found in the SC5b-9 complex of complement and in the immune deposits in glomerulonephritis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2904008-1

7 January 2021

Fcgamma receptors: old friends and new family members

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https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2904008-1

7 January 2021

New drugs for rheumatoid arthritis

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https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2904008-1

7 January 2021

Anatomic localization of immature and mature dendritic cells in an ectopic lymphoid organ: correlation with selective chemokine expression in rheumatoid synovium

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2904008-1

7 January 2021

Interleukin-6 affects cell death escaping mechanisms acting on Bax-Ku70-Clusterin interactions in human colon cancer progression

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2904008-1

7 January 2021

Increased FcgammaRII expression and aberrant tumour necrosis factor alpha production by mature dendritic cells from patients with active rheumatoid arthritis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2904008-1

7 January 2021

Clusterin is a short half-life, poly-ubiquitinated protein, which controls the fate of prostate cancer cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2904008-1

7 January 2021

C1q is a nucleotide binding protein and is responsible for the ability of clusterin preparations to promote immune complex formation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2904008-1

7 January 2021

Apolipoprotein J/clusterin prevents a progressive glomerulopathy of aging

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2904008-1

7 January 2021

Glycosylation and the immune system

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2904008-1

7 January 2021

T-cell receptor proximal signaling via the Src-family kinases, Lck and Fyn, influences T-cell activation, differentiation, and tolerance

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2904008-1

7 January 2021

TGF-beta indirectly favors the development of human Th17 cells by inhibiting Th1 cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2904008-1

7 January 2021

Essential requirement of apolipoprotein J (clusterin) signaling for IkappaB expression and regulation of NF-kappaB activity.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2904008-1

7 January 2021

Clusterin is protective in pancreatitis through anti-apoptotic and anti-inflammatory properties

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2904008-1

7 January 2021

Clusterin (SGP-2, ApoJ) expression is downregulated in low- and high-grade human prostate cancer.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2904008-1

7 January 2021

Intracellular clusterin induces G2-M phase arrest and cell death in PC-3 prostate cancer cells1.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2904008-1

7 January 2021

Chromosomal assignment of the human homologue encoding SGP-2

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https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2904008-1

7 January 2021

Dendritic cells: understanding immunogenicity

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https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2904008-1

7 January 2021

Taking dendritic cells into medicine

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https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2904008-1

7 January 2021

Dendritic Cell Function in Vivo during the Steady State: A Role in Peripheral Tolerance

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https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2904008-1

7 January 2021

A sodium dodecyl sulfate-polyacrylamide gel electrophoresis-liquid chromatography tandem mass spectrometry analysis of bovine cartilage tissue response to mechanical compression injury and the inflammatory cytokines tumor necrosis factor alpha and i

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2904008-1

7 January 2021

NF-kappaB: a key role in inflammatory diseases

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https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2904008-1

7 January 2021

Inhibitor of nuclear factor kappaB kinase beta is a key regulator of synovial inflammation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2904008-1

7 January 2021

Silencing expression of the clusterin/apolipoprotein j gene in human cancer cells using small interfering RNA induces spontaneous apoptosis, reduced growth ability, and cell sensitization to genotoxic and oxidative stress

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2904008-1

7 January 2021

Intracellular clusterin inhibits mitochondrial apoptosis by suppressing p53-activating stress signals and stabilizing the cytosolic Ku70-Bax protein complex

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2904008-1

7 January 2021

The effects of ACE inhibitor and angiotensin receptor blocker on clusterin and apoptosis in the kidney tissue of streptozotocin-diabetic rats

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2904008-1

7 January 2021

Association between HLA class II genes and autoantibodies to cyclic citrullinated peptides (CCPs) influences the severity of rheumatoid arthritis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2904008-1

7 January 2021

Innate signaling and regulation of Dendritic cell immunity

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https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2904008-1

7 January 2021

How regulatory T cells work

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https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2904008-1

7 January 2021

Identification of IL-17-producing FOXP3+ regulatory T cells in humans.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2904008-1

7 January 2021

Transcriptional down-regulation of the platelet ADP receptor P2Y(12) and clusterin in patients with systemic lupus erythematosus

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2904008-1

7 January 2021

New insights into the molecular basis of T cell anergy: anergy factors, avoidance sensors, and epigenetic imprinting

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2904008-1

7 January 2021

Cell-cell interactions in synovitis. Interactions between T cells and B cells in rheumatoid arthritis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2904008-1

7 January 2021

Clusterin binds by a multivalent mechanism to the Fc and Fab regions of IgG

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2904008-1

7 January 2021

Development, cytokine profile and function of human interleukin 17-producing helper T cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2904008-1

7 January 2021

Clusterin inhibits apoptosis by interacting with activated Bax

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2904008-1

7 January 2021

The cerebrospinal-fluid soluble form of Alzheimer's amyloid beta is complexed to SP-40,40 (apolipoprotein J), an inhibitor of the complement membrane-attack complex

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2904008-1

7 January 2021

Clusterin Has Chaperone-like Activity Similar to That of Small Heat Shock Proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2904008-1

7 January 2021

Apolipoprotein J is associated with paraoxonase in human plasma

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2904008-1

7 January 2021

Overexpression of clusterin in human hepatocellular carcinoma

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2904008-1

7 January 2021

Identification of glycoprotein 330 as an endocytic receptor for apolipoprotein J/clusterin

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2904008-1

7 January 2021

Clusterin in bovine spongiform encephalopathy (BSE).

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2904008-1

7 January 2021

Interaction of transforming growth factor beta receptors with apolipoprotein J/clusterin

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2904008-1

7 January 2021

Nuclear clusterin/XIP8, an x-ray-induced Ku70-binding protein that signals cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2904008-1

7 January 2021

10.1016/S0065-230X(09)04008-1

Identifiers

DOI

1 reference

21 August 2017

1 reference

PubMed ID

19878776