Phosphotriester adducts (PTEs): DNA's overlooked lesion (Q37634188)

21 August 2017

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title

Phosphotriester adducts (PTEs): DNA's overlooked lesion (English)

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21 August 2017

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George D D Jones

1

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21 August 2017

Rachel C Le Pla

series ordinal

2

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21 August 2017

Peter B Farmer

series ordinal

3

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21 August 2017

publication date

17 November 2009

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21 August 2017

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21 August 2017

volume

25

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21 August 2017

issue

1

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21 August 2017

page(s)

3-16

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Use of DNA adducts to identify human health risk from exposure to hazardous environmental pollutants: the increasing role of mass spectrometry in assessing biologically effective doses of genotoxic carcinogens

21 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEP038

The role of adduct site-specific mutagenesis in understanding how carcinogen-DNA adducts cause mutations: perspective, prospects and problems

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEP038

A comprehensive quantitative analysis of methylated and ethylated DNA using high pressure liquid chromatography.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEP038

An assay for phosphotriester formation in the reaction of alkylating agents with deoxyribosenucleic acid in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEP038

The kinetics of the alkaline hydrolysis of phosphotriesters in DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEP038

Quantitation of lower levels of the DNA adduct of thymidylyl(3'-5')thymidine methyl phosphotriester by liquid chromatography/negative atmospheric pressure chemical ionization tandem mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEP038

The stability of methyl and ethyl phosphotriesters in DNA in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEP038

Characterization of the purine ring-opened 7-methylguanine and its persistence in rat bladder epithelial DNA after treatment with the carcinogen N-methylnitrosourea.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEP038

Analysis of DNA-phosphate adducts in vitro using miniaturized LC-ESI-MS/MS and column switching: phosphotriesters and alkyl cobalamins

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEP038

Formation and stability of alkylated pyrimidines and purines (including imidazole ring-opened 7-alkylguanine) and alkylphosphotriesters in liver DNA of adult rats treated with ethylnitrosourea or dimethylnitrosamine

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEP038

Tissue-dependent enzyme-mediated repair or removal of O-ethyl pyrimidines and ethyl purines in carcinogen-treated rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEP038

O2- and O4-ethylthymine and the ethylphosphotriester dTp(Et)dT are highly persistent DNA modifications in slowly dividing tissues of the ethylnitrosourea-treated rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEP038

Phosphate alkylation in different DNA substrates: the role of local DNA sequence and electrophile character in determining the nonrandom nature of phosphotriester adduct formation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEP038

A 32P-postlabelling assay for the detection of alkylphosphotriesters in DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEP038

The formation and stability of methyl phosphotriesters in the DNA of rat tissues after treatment with the carcinogen N,N-dimethylnitrosamine

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEP038

Further development of 32P-postlabeling for the detection of alkylphosphotriesters: evidence for the long-term nonrandom persistence of ethyl-phosphotriester adducts in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEP038

Analysis of the DNA adducts of phenyl glycidyl ether in a calf thymus DNA hydrolysate by capillary zone electrophoresis-electrospray mass spectrometry: evidence for phosphate alkylation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEP038

Evidence for phosphate adducts in DNA from mice treated with 4-(N-Methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone (NNK).

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEP038

Detection of phosphodiester adducts formed by the reaction of benzo[a]pyrene diol epoxide with 2'-deoxynucleotides using collision-induced dissociation electrospray ionization tandem mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEP038

DNA strand scission by benzo[a]pyrene diol epoxides

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEP038

DNA alkylation products formed by 1-(2-chloroethyl)-1-nitrosourea as molecular dosimeters of therapeutic response

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEP038

Effect of cations on the formation of DNA alkylation products in DNA reacted with 1-(2-Chloroethyl)-1-nitrosourea

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEP038

Characterization of phosphodiester adducts produced by the reaction of cyanoethylene oxide with nucleotides.

21 January 2018

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https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEP038

Applications of accelerator mass spectrometry for pharmacological and toxicological research.

21 January 2018

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https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEP038

Selective hydrolysis by exo- and endonucleases of phosphodiester bonds adjacent to an apurinic site.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEP038

Evaluation of phosphodiesterase I-based protocols for the detection of multiply damaged sites in DNA: the detection of abasic, oxidative and alkylative tandem damage in DNA oligonucleotides

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEP038

Alkyl phosphotriester modified oligodeoxyribonucleotides. VI. NMR and UV spectroscopic studies of ethyl phosphotriester (Et) modified Rp-Rp and Sp-Sp duplexes, (d[GGAA(Et)TTCC])2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEP038

Studies on the stability of trialkyl phosphates and di-(2'deoxythymidine) phosphotriesters in alkaline and neutral solution. A model study for hydrolysis of phosphotriesters in DNA and on the influence of a beta hydroxyethyl ester group

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEP038

Inducible repair of phosphotriesters in Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEP038

Methyl phosphotriesters in alkylated DNA are repaired by the Ada regulatory protein of E. coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEP038

Repair of O6-propylguanine and O6-butylguanine in DNA by O6-alkylguanine-DNA alkyltransferases from rat liver and E. coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEP038

Cross-linking of DNA induced by chloroethyinitrosourea is prevented by O6-methyiguanine-DNA methyttransferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEP038

Stereospecific removal of methyl phosphotriesters from DNA by an Escherichia coli ada+ extract

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEP038

Folding topology and DNA binding of the N-terminal fragment of Ada protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEP038

A methylation-dependent electrostatic switch controls DNA repair and transcriptional activation by E. coli ada.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEP038

Active site and complete sequence of the suicidal methyltransferase that counters alkylation mutagenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEP038

The suicidal DNA repair methyltransferases of microbes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEP038

Functional sites of the Ada regulatory protein of Escherichia coli. Analysis by amino acid substitutions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEP038

Converting the sacrificial DNA repair protein N-ada into a catalytic methyl phosphotriester repair enzyme.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEP038

A new pathway for DNA repair in Escherichia coli

21 January 2018

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https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEP038

Expression of the ada gene of Escherichia coli in response to alkylating agents. Identification of transcriptional regulatory elements.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEP038

Molecular cloning of a gene which regulates the adaptive response to alkylating agents in Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEP038

The intracellular signal for induction of resistance to alkylating agents in E. coli.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEP038

Crystal structure of thermitase at 1.4 A resolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEP038

Transcriptional activation of the Escherichia coli adaptive response gene aidB is mediated by binding of methylated Ada protein. Evidence for a new consensus sequence for Ada-binding sites.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEP038

AlkB-mediated oxidative demethylation reverses DNA damage in Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEP038

Oxidative demethylation by Escherichia coli AlkB directly reverts DNA base damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEP038

Molecular cloning and characterization of the alkB gene of Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEP038

Induction of specific Escherichia coli genes by sublethal treatments with alkylating agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEP038

Inducible alkyltransferase DNA repair proteins in the filamentous fungus Aspergillus nidulans

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEP038

Human O6-alkylguanine-DNA alkyltransferase fails to repair O4-methylthymine and methyl phosphotriesters in DNA as efficiently as does the alkyltransferase from Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEP038

Contacts between Escherichia coli RNA polymerase and an early promoter of phage T7.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEP038

Interaction of MutS protein with the major and minor grooves of a heteroduplex DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEP038

DNA determinants and substrate specificities of Escherichia coli MutY.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEP038

Abasic site binding by the human apurinic endonuclease, Ape, and determination of the DNA contact sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEP038

Differences in replication of a DNA template containing an ethyl phosphotriester by T4 DNA polymerase and Escherichia coli DNA polymerase I.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEP038

Alkyl phosphotriester modified oligodeoxyribonucleotides. V. Synthesis and absolute configuration of Rp and Sp diastereomers of an ethyl phosphotriester (Et) modified EcoRI recognition sequence, d[GGAA(Et)TTCC]. A synthetic approach to regio- and st

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEP038

21 January 2018

Identifiers

DOI

10.1093/MUTAGE/GEP038

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21 August 2017

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