Does simvastatin cause more myotoxicity compared with other statins? (Q37634190)

21 August 2017

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title

Does simvastatin cause more myotoxicity compared with other statins? (English)

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21 August 2017

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James M Backes

1

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21 August 2017

Patricia A Howard

series ordinal

2

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21 August 2017

Janelle F Ruisinger

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3

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21 August 2017

Patrick M Moriarty

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4

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21 August 2017

language of work or name

English

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publication date

17 November 2009

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Annals of Pharmacotherapy

21 August 2017

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21 August 2017

43

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21 August 2017

12

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21 August 2017

2012-2020

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Comparative evaluation of the safety and efficacy of HMG-CoA reductase inhibitor monotherapy in the treatment of primary hypercholesterolemia

21 August 2017

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Mild to moderate muscular symptoms with high-dosage statin therapy in hyperlipidemic patients--the PRIMO study

21 January 2018

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ACC/AHA/NHLBI clinical advisory on the use and safety of statins

21 January 2018

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Combination therapy for dyslipidemia: safety and regulatory considerations

21 January 2018

1 reference

Results of two clinical trials on the safety and efficacy of pravastatin 80 and 160 mg per day.

21 January 2018

1 reference

Statin safety: lessons from new drug applications for marketed statins.

21 January 2018

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Rhabdomyolysis and HMG-CoA reductase inhibitors

21 January 2018

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Statin safety and drug interactions: clinical implications

21 January 2018

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Researchers worry about myopathy risk for patients taking high-dose simvastatin

21 January 2018

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Simvastatin: present and future perspectives

21 January 2018

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Simvastatin but not pravastatin is very susceptible to interaction with the CYP3A4 inhibitor itraconazole.

21 January 2018

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Comparative pharmacokinetic interaction profiles of pravastatin, simvastatin, and atorvastatin when coadministered with cytochrome P450 inhibitors

21 January 2018

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Different effects of itraconazole on the pharmacokinetics of fluvastatin and lovastatin

21 January 2018

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Itraconazole alters the pharmacokinetics of atorvastatin to a greater extent than either cerivastatin or pravastatin

21 January 2018

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Effect of itraconazole on the pharmacokinetics of rosuvastatin

21 January 2018

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The effect of erythromycin on the pharmacokinetics of rosuvastatin

21 January 2018

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Substantially elevated levels of atorvastatin and metabolites in cyclosporine-treated renal transplant recipients

21 January 2018

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Pharmacokinetics and pharmacodynamics of pravastatin in pediatric and adolescent cardiac transplant recipients on a regimen of triple immunosuppression

21 January 2018

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Interactions between cyclosporin and lipid-lowering drugs: implications for organ transplant recipients

21 January 2018

1 reference

Rosuvastatin pharmacokinetics in heart transplant recipients administered an antirejection regimen including cyclosporine

21 January 2018

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Changes in lipid metabolism and effect of simvastatin in renal transplant recipients induced by cyclosporine or tacrolimus

21 January 2018

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Pharmacokinetics and pharmacodynamics of fluvastatin in heart transplant recipients taking cyclosporine A.

21 January 2018

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Plasma concentrations of active lovastatin acid are markedly increased by gemfibrozil but not by bezafibrate

21 January 2018

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The effect of gemfibrozil on the pharmacokinetics of rosuvastatin

21 January 2018

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Gemfibrozil increases plasma pravastatin concentrations and reduces pravastatin renal clearance

21 January 2018

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Rifampin markedly decreases and gemfibrozil increases the plasma concentrations of atorvastatin and its metabolites

21 January 2018

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Pharmacokinetics of the combination of fluvastatin and gemfibrozil

21 January 2018

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Etiology and frequency of rhabdomyolysis

21 January 2018

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Sustained reduction of serum cholesterol in low-dose 6-year simvastatin treatment with minimum side effects in 51,321 Japanese hypercholesterolemic patients

21 January 2018

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Incidence of hospitalized rhabdomyolysis in patients treated with lipid-lowering drugs

21 January 2018

1 reference

Statin safety: an assessment using an administrative claims database.

21 January 2018

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Statin safety: an overview and assessment of the data--2005.

21 January 2018

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Statin safety: a systematic review

21 January 2018

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Intensive lipid lowering with atorvastatin in patients with stable coronary disease

21 January 2018

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High-dose atorvastatin vs usual-dose simvastatin for secondary prevention after myocardial infarction: the IDEAL study: a randomized controlled trial

21 January 2018

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Rosuvastatin to prevent vascular events in men and women with elevated C-reactive protein

21 January 2018

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Fluvastatin for prevention of cardiac events following successful first percutaneous coronary intervention: a randomized controlled trial

21 January 2018

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Early intensive vs a delayed conservative simvastatin strategy in patients with acute coronary syndromes: phase Z of the A to Z trial

21 January 2018

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Intensive versus moderate lipid lowering with statins after acute coronary syndromes

21 January 2018

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Cerivastatin and reports of fatal rhabdomyolysis

21 January 2018

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Simvastatin interaction with clarithromycin and amiodarone causing myositis

21 January 2018

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Simvastatin-amiodarone interaction resulting in rhabdomyolysis, azotemia, and possible hepatotoxicity

21 January 2018

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Rhabdomyolysis in association with simvastatin and amiodarone

21 January 2018

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Myopathy from the combination of simvastatin and amiodarone

21 January 2018

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Implications of recent clinical trials for the National Cholesterol Education Program Adult Treatment Panel III guidelines

21 January 2018

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Amiodarone Interacts with Simvastatin but not with Pravastatin Disposition Kinetics

21 January 2018

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21 January 2018

Identifiers

DOI

10.1345/APH.1M410

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21 August 2017

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