In vitro and in vivo biological activity of PEDF against a range of tumors. (Q37634555)

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12 February 2020

review article

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title

In vitro and in vivo biological activity of PEDF against a range of tumors (English)

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12 February 2020

3

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12 February 2020

Peter Choong

series ordinal

4

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12 February 2020

2

Crispin R Dass

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12 February 2020

author name string

Matthew L Broadhead

series ordinal

1

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12 February 2020

language of work or name

English

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publication date

1 December 2009

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Expert Opinion on Therapeutic Targets

12 February 2020

published in

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12 February 2020

volume

13

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12 February 2020

issue

12

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12 February 2020

page(s)

1429-1438

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Focus on Molecules: Pigment epithelium-derived factor (PEDF).

12 February 2020

cites work

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PEDF: a pigment epithelium-derived factor with potent neuronal differentiative activity

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PEDF: a potential molecular therapeutic target with multiple anti-cancer activities.

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Anti-angiogenic therapy for osteosarcoma.

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Pigment epithelium-derived factor: a potent inhibitor of angiogenesis

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Extracellular phosphorylation converts pigment epithelium-derived factor from a neurotrophic to an antiangiogenic factor

21 January 2018

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How PEDF prevents angiogenesis: a hypothesized pathway

21 January 2018

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Pigment epithelium-derived factor behaves like a noninhibitory serpin. Neurotrophic activity does not require the serpin reactive loop

21 January 2018

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Decreased pigment epithelium-derived factor expression in human breast cancer progression

21 January 2018

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Pigment epithelium–derived factor regulates the vasculature and mass of the prostate and pancreas

21 January 2018

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Two functional epitopes of pigment epithelial-derived factor block angiogenesis and induce differentiation in prostate cancer

21 January 2018

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Adenovirus-mediated PEDF expression inhibits prostate cancer cell growth and results in augmented expression of PAI-2.

21 January 2018

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Decreased pigment epithelium-derived factor is associated with metastatic phenotype in human and rat prostate tumors

21 January 2018

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Pigment epithelium-derived factor is estrogen sensitive and inhibits the growth of human ovarian cancer and ovarian surface epithelial cells.

21 January 2018

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Expression of pigment epithelium-derived factor decreases liver metastasis and correlates with favorable prognosis for patients with ductal pancreatic adenocarcinoma

21 January 2018

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Overexpression of pigment epithelium-derived factor decreases angiogenesis and inhibits the growth of human malignant melanoma cells in vivo

21 January 2018

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Inhibition of xenografted human melanoma growth and prevention of metastasis development by dual antiangiogenic/antitumor activities of pigment epithelium-derived factor

21 January 2018

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Inhibition of glioma invasion by overexpression of pigment epithelium-derived factor

21 January 2018

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Loss of pigment epithelium derived factor expression in glioma progression

21 January 2018

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Pigment epithelium-derived factor inhibits glioma cell growth in vitro and in vivo

21 January 2018

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Resistance of epiphyseal cartilage to invasion by osteosarcoma is likely to be due to expression of antiangiogenic factors.

21 January 2018

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PEDF-derived synthetic peptides exhibit antitumor activity in an orthotopic model of human osteosarcoma.

21 January 2018

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Inhibition of orthotopic osteosarcoma growth and metastasis by multitargeted antitumor activities of pigment epithelium-derived factor

21 January 2018

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Pigment epithelium-derived factor overexpression inhibits orthotopic osteosarcoma growth, angiogenesis and metastasis

21 January 2018

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cDNA microarray analysis of pigment epithelium-derived factor-regulated gene expression profile in prostate carcinoma cells

21 January 2018

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Pigment epithelium-derived factor gene therapy inhibits human pancreatic cancer in mice

21 January 2018

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Angiogenesis and metastasis inhibitors for the treatment of malignant melanoma

21 January 2018

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Pigment epithelium-derived factor protects cultured retinal pericytes from advanced glycation end product-induced injury through its antioxidative properties

21 January 2018

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The role of high-dose therapy and autologous stem cell transplantation for pediatric bone and soft tissue sarcomas.

21 January 2018

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Pigment epithelium-derived factor (PEDF)-induced apoptosis and inhibition of vascular endothelial growth factor (VEGF) expression in MG63 human osteosarcoma cells

21 January 2018

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The urokinase plasminogen activator receptor as a gene therapy target for cancer

21 January 2018

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Inhibition of urokinase receptor gene expression and cell invasion by anti-uPAR DNAzymes in osteosarcoma cells

21 January 2018

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uPAR mediates anticancer activity of PEDF.

21 January 2018

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Chitosan microparticles encapsulating PEDF plasmid demonstrate efficacy in an orthotopic metastatic model of osteosarcoma.

21 January 2018

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10.1517/14728220903307475

21 January 2018

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19922300%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

1 reference