Overcoming the barriers in micellar drug delivery: loading efficiency, in vivo stability, and micelle-cell interaction (Q37657516)

21 August 2017

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title

Overcoming the barriers in micellar drug delivery: loading efficiency, in vivo stability, and micelle-cell interaction (English)

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21 August 2017

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Sungwon Kim

1

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21 August 2017

Yunzhou Shi

2

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21 August 2017

Ji Young Kim

3

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21 August 2017

Kinam Park

4

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21 August 2017

Ji-Xin Cheng

5

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21 August 2017

language of work or name

English

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publication date

1 January 2010

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Expert Opinion on Drug Delivery

21 August 2017

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21 August 2017

7

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21 August 2017

1

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21 August 2017

49-62

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Block copolymer micelles: preparation, characterization and application in drug delivery

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Block copolymers for drug solubilisation: relative hydrophobicities of polyether and polyester micelle-core-forming blocks

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Supramolecular assemblies for the cytoplasmic delivery of antisense oligodeoxynucleotide: polyion complex (PIC) micelles based on poly(ethylene glycol)-SS-oligodeoxynucleotide conjugate.

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Biodegradable cationic PEG-PEI-PBLG hyperbranched block copolymer: synthesis and micelle characterization

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Drug-like properties and the causes of poor solubility and poor permeability

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Long-circulating poly(ethylene glycol)-poly(D,L-lactide) block copolymer micelles with modulated surface charge

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Ligand-targeted therapeutics in anticancer therapy

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Multicenter phase II trial of Genexol-PM, a novel Cremophor-free, polymeric micelle formulation of paclitaxel, with cisplatin in patients with advanced non-small-cell lung cancer.

21 January 2018

1 reference

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Phase I and pharmacokinetic study of Genexol-PM, a cremophor-free, polymeric micelle-formulated paclitaxel, in patients with advanced malignancies

21 January 2018

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Multicenter phase II trial of Genexol-PM, a Cremophor-free, polymeric micelle formulation of paclitaxel, in patients with metastatic breast cancer.

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Phase I clinical trial and pharmacokinetic evaluation of NK911, a micelle-encapsulated doxorubicin

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A phase I and pharmacokinetic study of NK105, a paclitaxel-incorporating micellar nanoparticle formulation

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NK105, a paclitaxel-incorporating micellar nanoparticle, is a more potent radiosensitising agent compared to free paclitaxel

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Hydrotropic polymer micelle system for delivery of paclitaxel.

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Solubilization of hydrophobic drugs by methoxy poly(ethylene glycol)-block-polycaprolactone diblock copolymer micelles: theoretical and experimental data and correlations

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Polymer-drug compatibility: a guide to the development of delivery systems for the anticancer agent, ellipticine

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Unified concept of solubilization in water by hydrotropes and cosolvents

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Solubility Enhancement of Some Water-Insoluble Drugs in the Presence of Nicotinamide and Related Compounds

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Stacking complexation by nicotinamide: a useful way of enhancing drug solubility.

21 January 2018

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Hydrotropic solubilization of paclitaxel: analysis of chemical structures for hydrotropic property.

21 January 2018

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A new hydrotropic block copolymer micelle system for aqueous solubilization of paclitaxel

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Kinetics of step-wise micelle association

21 January 2018

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FRET or no FRET: a quantitative comparison

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Assessment of the integrity of poly(caprolactone)-b-poly(ethylene oxide) micelles under biological conditions: a fluorogenic-based approach

21 January 2018

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Fast release of lipophilic agents from circulating PEG-PDLLA micelles revealed by in vivo forster resonance energy transfer imaging

21 January 2018

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A hydrophobic interaction site for lysozyme binding to polyethylene glycol and model contact lens polymers

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Fibronectin and immune complexes in rheumatic diseases.

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Enzymatic degradation of block copolymers prepared from epsilon-caprolactone and poly(ethylene glycol).

21 January 2018

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Biodegradable nanoparticles of amphiphilic triblock copolymers based on poly(3-hydroxybutyrate) and poly(ethylene glycol) as drug carriers

21 January 2018

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A mechanistic study on the chemical and enzymatic degradation of PEG-Oligo(epsilon-caprolactone) micelles.

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Effects of polyethyleneimine on endocytosis and lysosome stability

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Super pH-sensitive multifunctional polymeric micelle

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Hydrotropic polymer micelles containing acrylic acid moieties for oral delivery of paclitaxel

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Micellar Nanocontainers Distribute to Defined Cytoplasmic Organelles

21 January 2018

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Cellular internalization of poly(ethylene oxide)-b-poly(epsilon-caprolactone) diblock copolymer micelles

21 January 2018

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Cellular distribution of nonionic micelles.

21 January 2018

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Cell-surface proteoglycans as molecular portals for cationic peptide and polymer entry into cells

21 January 2018

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Release of hydrophobic molecules from polymer micelles into cell membranes revealed by Forster resonance energy transfer imaging

21 January 2018

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Interactions of pluronic block copolymers with brain microvessel endothelial cells: evidence of two potential pathways for drug absorption.

21 January 2018

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P-glycoprotein efflux inhibition by amphiphilic diblock copolymers: relationship between copolymer concentration and substrate hydrophobicity

21 January 2018

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Different internalization pathways of polymeric micelles and unimers and their effects on vesicular transport

21 January 2018

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Optimal structure requirements for pluronic block copolymers in modifying P-glycoprotein drug efflux transporter activity in bovine brain microvessel endothelial cells

21 January 2018

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Disposition of drugs in block copolymer micelle delivery systems: from discovery to recovery

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Cross-linked block copolymer micelles: functional nanostructures of great potential and versatility

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Synthesis of Reversible Shell Cross-Linked Micelles for Controlled Release of Bioactive Agents†

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Biodegradable and biocompatible multi-arm star amphiphilic block copolymer as a carrier for hydrophobic drug delivery.

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Amphiphilic multi-arm-block copolymer conjugated with doxorubicin via pH-sensitive hydrazone bond for tumor-targeted drug delivery.

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Molecular optical imaging: applications leading to the development of present day therapeutics

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Comparative preclinical and clinical pharmacokinetics of a cremophor-free, nanoparticle albumin-bound paclitaxel (ABI-007) and paclitaxel formulated in Cremophor (Taxol).

21 January 2018

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Radioisotope carrying polyethylene oxide-polycaprolactone copolymer micelles for targetable bone imaging

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Characterization of pegylated copolymeric micelles and in vivo pharmacokinetics and biodistribution studies

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Polymeric micelles for the solubilization and delivery of cyclosporine A: pharmacokinetics and biodistribution

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In vivo evaluation of polymeric micellar paclitaxel formulation: toxicity and efficacy

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Arg-Gly-Asp (RGD) peptide conjugated poly(lactic acid)-poly(ethylene oxide) micelle for targeted drug delivery

21 January 2018

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Enhanced antitumor effect of camptothecin loaded in long-circulating polymeric micelles.

21 January 2018

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Biodistribution characteristics of all-trans retinoic acid incorporated in liposomes and polymeric micelles following intravenous administration

21 January 2018

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Pharmacokinetics and biodistribution of paclitaxel-loaded pluronic P105 polymeric micelles

21 January 2018

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Poly(N-vinylpyrrolidone)-block-poly(D,L-lactide) as a new polymeric solubilizer for hydrophobic anticancer drugs: in vitro and in vivo evaluation

21 January 2018

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Hydrolysable core-crosslinked thermosensitive polymeric micelles: synthesis, characterisation and in vivo studies

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Noncovalent Adducts of Poly(ethylene glycols) with Proteins

21 January 2018

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10.1517/17425240903380446

21 January 2018

Identifiers

DOI

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21 August 2017

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