IL-9: basic biology, signaling pathways in CD4+ T cells and implications for autoimmunity (Q37658504)

21 August 2017

1 reference

title

IL-9: basic biology, signaling pathways in CD4+ T cells and implications for autoimmunity (English)

1 reference

21 August 2017

Hongmei Li

1

1 reference

PubMed ID

20020328

21 August 2017

Abdolmohamad Rostami

series ordinal

2

1 reference

21 August 2017

18 December 2009

1 reference

Journal of Neuroimmune Pharmacology

21 August 2017

1 reference

21 August 2017

5

1 reference

21 August 2017

198-209

1 reference

21 August 2017

2

1 reference

https://scigraph.springernature.com/pub.10.1007/s11481-009-9186-y

21 August 2017

0 references

cites work

IL-9 is a susceptibility factor in Leishmania major infection by promoting detrimental Th2/type 2 responses

1 reference

https://api.crossref.org/works/10.1007%2FS11481-009-9186-Y

IL-2 receptor beta-dependent STAT5 activation is required for the development of Foxp3+ regulatory T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-009-9186-Y

A single tyrosine of the interleukin-9 (IL-9) receptor is required for STAT activation, antiapoptotic activity, and growth regulation by IL-9

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-009-9186-Y

Cloning and characterization of IL-10-related T cell-derived inducible factor (IL-TIF), a novel cytokine structurally related to IL-10 and inducible by IL-9.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-009-9186-Y

IL-9 protects mice from Gram-negative bacterial shock: suppression of TNF-alpha, IL-12, and IFN-gamma, and induction of IL-10.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-009-9186-Y

IL-9 and lung fibrosis: a Th2 good guy?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-009-9186-Y

A comparison of multiplex suspension array large-panel kits for profiling cytokines and chemokines in rheumatoid arthritis patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-009-9186-Y

Selection and transplantation of autologous hematopoietic CD34+ cells for patients with multiple myeloma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-009-9186-Y

Interleukin-9 upregulates mucus expression in the airways

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-009-9186-Y

Regulation of signal transducer and activator of transcription and suppressor of cytokine-signaling gene expression in the brain of mice with astrocyte-targeted production of interleukin-12 or experimental autoimmune encephalomyelitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-009-9186-Y

Stat3 and Stat4 direct development of IL-17-secreting Th cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-009-9186-Y

Suppression of proliferation and phosphorylation of Jak3 and STAT5 in malignant T-cell lymphoma cells by derivatives of octylamino-undecyl-dimethylxanthine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-009-9186-Y

Interactions among the transcription factors Runx1, RORgammat and Foxp3 regulate the differentiation of interleukin 17-producing T cells

21 January 2018

1 reference

12 December 2020

JAK1 kinase forms complexes with interleukin-4 receptor and 4PS/insulin receptor substrate-1-like protein and is activated by interleukin-4 and interleukin-9 in T lymphocytes

1 reference

12 December 2020

Pathophysiology of neonatal brain lesions: lessons from animal models of excitotoxicity

1 reference

12 December 2020

TGF-beta-induced Foxp3 inhibits T(H)17 cell differentiation by antagonizing RORgammat function

1 reference

12 December 2020

Mast cell growth-enhancing activity (MEA) is structurally related and functionally identical to the novel mouse T cell growth factor P40/TCGFIII (interleukin 9)

1 reference

12 December 2020

Mast cells as a source of both preformed and immunologically inducible TNF-alpha/cachectin.

1 reference

12 December 2020

Interleukin-9 in human myeloid leukemia cells

1 reference

12 December 2020

Reciprocal TH17 and regulatory T cell differentiation mediated by retinoic acid

1 reference

12 December 2020

Functional and structural characterization of P40, a mouse glycoprotein with T-cell growth factor activity.

1 reference

12 December 2020

Human T cell lines and clones respond to IL-9.

1 reference

12 December 2020

IL-9 promotes anti-Mycobacterium leprae cytotoxicity: involvement of IFNgamma.

1 reference

12 December 2020

Signal transduction pathways and transcription factors as therapeutic targets in inflammatory disease: towards innovative antirheumatic therapy

1 reference

12 December 2020

Changing paradigms in the immunological science of allergy

1 reference

12 December 2020

[Role of interleukin-9 in asthma and allergic reactions]

1 reference

12 December 2020

Acute lymphoblastic leukemia-associated JAK1 mutants activate the Janus kinase/STAT pathway via interleukin-9 receptor alpha homodimers

1 reference

12 December 2020

IL-4 inhibits TGF-beta-induced Foxp3+ T cells and, together with TGF-beta, generates IL-9+ IL-10+ Foxp3(-) effector T cells

1 reference

12 December 2020

Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins

1 reference

12 December 2020

Mast cells are essential intermediaries in regulatory T-cell tolerance

1 reference

12 December 2020

IL-4-independent regulation of in vivo IL-9 expression

1 reference

12 December 2020

In activated mast cells, IL-1 up-regulates the production of several Th2-related cytokines including IL-9

1 reference

12 December 2020

Interleukin 9 induces expression of three cytokine signal inhibitors: cytokine-inducible SH2-containing protein, suppressor of cytokine signalling (SOCS)-2 and SOCS-3, but only SOCS-3 overexpression suppresses interleukin 9 signalling

1 reference

12 December 2020

Th9 and allergic disease

1 reference

12 December 2020

T-lymphocyte entry into the central nervous system

1 reference

12 December 2020

Interleukin-9 potentiates the interleukin-4-induced immunoglobulin (IgG, IgM and IgE) production by normal human B lymphocytes

1 reference

12 December 2020

Control of T(reg) and T(H)17 cell differentiation by the aryl hydrocarbon receptor

1 reference

12 December 2020

The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells

1 reference

12 December 2020

Sharing of the IL-2 receptor gamma chain with the functional IL-9 receptor complex

1 reference

12 December 2020

Interferon-induced nuclear signalling by Jak protein tyrosine kinases

1 reference

12 December 2020

Effect of interleukin-9 on clonogenic maturation and cell-cycle status of fetal and adult hematopoietic progenitors

1 reference

12 December 2020

IL-9 induces differentiation of TH17 cells and enhances function of FoxP3+ natural regulatory T cells

1 reference

12 December 2020

Cytokine signal transduction

1 reference

12 December 2020

STAT3 regulates cytokine-mediated generation of inflammatory helper T cells

1 reference

12 December 2020

Interleukin 18 acts on memory T helper cells type 1 to induce airway inflammation and hyperresponsiveness in a naive host mouse

1 reference

12 December 2020

Constitutive STAT3 activation in peripheral CD3(+) cells from patients with primary Sjögren's syndrome

1 reference

12 December 2020

Interleukin-9 induces tyrosine phosphorylation of insulin receptor substrate-1 via JAK tyrosine kinases

1 reference

12 December 2020

1 reference

12 December 2020

IL-9 as a mediator of Th17-driven inflammatory disease

1 reference

12 December 2020

Interleukin-9 promotes eosinophilic rejection of mouse heart allografts.

1 reference

12 December 2020

Association and activation of Jak-Tyk kinases by CNTF-LIF-OSM-IL-6 beta receptor components

1 reference

12 December 2020

Beta-catenin stabilization extends regulatory T cell survival and induces anergy in nonregulatory T cells

1 reference

12 December 2020

STAT6 Inhibits TGF-beta1-mediated Foxp3 induction through direct binding to the Foxp3 promoter, which is reverted by retinoic acid receptor

1 reference

12 December 2020

The development of inflammatory T(H)-17 cells requires interferon-regulatory factor 4

1 reference

12 December 2020

The IL-9 receptor gene (IL9R): genomic structure, chromosomal localization in the pseudoautosomal region of the long arm of the sex chromosomes, and identification of IL9R pseudogenes at 9qter, 10pter, 16pter, and 18pter

1 reference

12 December 2020

Transforming growth factor-beta 'reprograms' the differentiation of T helper 2 cells and promotes an interleukin 9-producing subset.

1 reference

12 December 2020

Novel signal transducer and activator of transcription 3 (STAT3) mutations, reduced T(H)17 cell numbers, and variably defective STAT3 phosphorylation in hyper-IgE syndrome

1 reference

12 December 2020

Human P40/IL-9. Expression in activated CD4+ T cells, genomic organization, and comparison with the mouse gene

1 reference

12 December 2020

Impaired T(H)17 cell differentiation in subjects with autosomal dominant hyper-IgE syndrome

1 reference

12 December 2020

Interleukin 9: a candidate gene for asthma

1 reference

12 December 2020

IL-9 production of naive CD4+ T cells depends on IL-2, is synergistically enhanced by a combination of TGF-beta and IL-4, and is inhibited by IFN-gamma

1 reference

12 December 2020

Critical cytoplasmic domains of human interleukin-9 receptor alpha chain in interleukin-9-mediated cell proliferation and signal transduction

1 reference

12 December 2020

Nonredundant roles for Stat5a/b in directly regulating Foxp3

1 reference

12 December 2020

Nonredundant roles for CD1d-restricted natural killer T cells and conventional CD4+ T cells in the induction of immunoglobulin E antibodies in response to interleukin 18 treatment of mice

1 reference

12 December 2020

Immunological aspects of allergic asthma

1 reference

12 December 2020

TH17 cells in development: an updated view of their molecular identity and genetic programming

1 reference

12 December 2020

Distinct roles for STAT1, STAT3, and STAT5 in differentiation gene induction and apoptosis inhibition by interleukin-9

1 reference

12 December 2020

IL-9 expression by human eosinophils: regulation by IL-1beta and TNF-alpha

1 reference

12 December 2020

IL-9/IL-9 receptor signaling selectively protects cortical neurons against developmental apoptosis.

1 reference

12 December 2020

Human recombinant granulocyte-macrophage colony-stimulating factor increases cell-to-cell adhesion and surface expression of adhesion-promoting surface glycoproteins on mature granulocytes

1 reference

12 December 2020

Deficiency of Th17 cells in hyper IgE syndrome due to mutations in STAT3

1 reference

12 December 2020

IL-12 up-regulates IL-18 receptor expression on T cells, Th1 cells, and B cells: synergism with IL-18 for IFN-gamma production

1 reference

12 December 2020

Oxidative burst in lipopolysaccharide-activated human alveolar macrophages is inhibited by interleukin-9.

1 reference

12 December 2020

Cytokines regulate the cellular phenotype of developing neural lineage species

1 reference

12 December 2020

A soluble form of the murine common gamma chain is present at high concentrations in vivo and suppresses cytokine signaling

1 reference

12 December 2020

Human interleukin 4 receptor confers biological responsiveness and defines a novel receptor superfamily

1 reference

12 December 2020

Mutations in STAT3 and IL12RB1 impair the development of human IL-17-producing T cells

1 reference

12 December 2020

STAT3 mutations in the hyper-IgE syndrome

1 reference

12 December 2020

Induction of the IL-9 gene by HTLV-I Tax stimulates the spontaneous proliferation of primary adult T-cell leukemia cells by a paracrine mechanism

1 reference

12 December 2020

Selective regulatory function of Socs3 in the formation of IL-17-secreting T cells

1 reference

12 December 2020

Role of IL-9 in the pathophysiology of allergic diseases.

1 reference

12 December 2020

Interleukin-9 enhances interleukin-5 receptor expression, differentiation, and survival of human eosinophils.

1 reference

12 December 2020

IL-2 dependence of IL-9 expression in human T lymphocytes

1 reference

12 December 2020

Differential regulation of IL-9-expression after infection with Leishmania major in susceptible and resistant mice

1 reference

12 December 2020

Neuron-mediated generation of regulatory T cells from encephalitogenic T cells suppresses EAE.

1 reference

12 December 2020

Foxp3 inhibits RORgammat-mediated IL-17A mRNA transcription through direct interaction with RORgammat

1 reference

12 December 2020

Linked T cell receptor and cytokine signaling govern the development of the regulatory T cell repertoire.

1 reference

12 December 2020

Janus tyrosine kinases and signal transducers and activators of transcription regulate critical functions of T cells in allograft rejection and transplantation tolerance

1 reference

12 December 2020

Interleukin-2 signaling via STAT5 constrains T helper 17 cell generation

1 reference

12 December 2020

TGF-beta: receptors, signaling pathways and autoimmunity

1 reference

12 December 2020

IL-9 is associated with an impaired Th1 immune response in patients with tuberculosis

1 reference

12 December 2020

T helper 17 lineage differentiation is programmed by orphan nuclear receptors ROR alpha and ROR gamma

1 reference

12 December 2020

Inhibitors of JAKs/STATs and the kinases: a possible new cluster of drugs

1 reference

12 December 2020

Interleukin-9 (IL-9) induces cell growth arrest associated with sustained signal transducer and activator of transcription activation in lymphoma cells overexpressing the IL-9 receptor

1 reference

12 December 2020

Migration of Hematogenous Cells Through the Blood-Brain Barrier and the Initiation of CNS Inflammation

1 reference

12 December 2020

Anti-IL-9 vaccination prevents worm expulsion and blood eosinophilia in Trichuris muris-infected mice.

1 reference

12 December 2020

Expression of the common cytokine receptor gamma chain by murine dendritic cells including epidermal Langerhans cells

1 reference

12 December 2020

Point mutation of tyrosine 759 of the IL-6 family cytokine receptor, gp130, augments collagen-induced arthritis in DBA/1J mice

1 reference

12 December 2020

IL-21 initiates an alternative pathway to induce proinflammatory T(H)17 cells

1 reference

12 December 2020

Aryl hydrocarbon receptor regulates Stat1 activation and participates in the development of Th17 cells.

1 reference

12 December 2020

Immune reactivity in the nervous system: modulation of T-lymphocyte activation by glial cells.

1 reference

12 December 2020

Resveratrol (trans-3,5,4'-trihydroxystilbene) ameliorates experimental allergic encephalomyelitis, primarily via induction of apoptosis in T cells involving activation of aryl hydrocarbon receptor and estrogen receptor

1 reference

12 December 2020

A cascade of cytokines is responsible for IL-9 expression in human T cells. Involvement of IL-2, IL-4, and IL-10

1 reference

12 December 2020

Interleukin 9-induced in vivo expansion of the B-1 lymphocyte population

1 reference

12 December 2020

Interleukin-9 stimulates the production of interleukin-5 in CD4+ T cells

1 reference

12 December 2020

The Current STATus of lymphocyte signaling: new roles for old players.

1 reference

12 December 2020

Glia maturation factor regulation of STAT expression: a novel mechanism in experimental autoimmune encephalomyelitis.

1 reference

12 December 2020

Priming for T helper type 2 differentiation by interleukin 2-mediated induction of interleukin 4 receptor alpha-chain expression

1 reference

12 December 2020

Functional and biochemical characterization of mouse P40/IL-9 receptors.

1 reference

12 December 2020

Allergen-induced IL-9 directly stimulates mucin transcription in respiratory epithelial cells.

1 reference

12 December 2020

Cytokine regulation of neuronal differentiation of hippocampal progenitor cells

1 reference

12 December 2020

STAT5 activation is required for interleukin-9-dependent growth and transformation of lymphoid cells.

1 reference

12 December 2020

A mutant Stat5b with weaker DNA binding affinity defines a key defective pathway in nonobese diabetic mice

1 reference

12 December 2020

Autoimmune T cells protect neurons from secondary degeneration after central nervous system axotomy

1 reference

12 December 2020

T helper cell effector fates--who, how and where?

1 reference

12 December 2020

Autocrine release of interleukin-9 promotes Jak3-dependent survival of ALK+ anaplastic large-cell lymphoma cells

1 reference

12 December 2020

Cutting edge: regulatory T cells induce CD4+CD25-Foxp3- T cells or are self-induced to become Th17 cells in the absence of exogenous TGF-beta

1 reference

12 December 2020

Dominant-negative mutations in the DNA-binding domain of STAT3 cause hyper-IgE syndrome

1 reference

12 December 2020

Epstein-Barr virus (EBV)-encoded RNA promotes growth of EBV-infected T cells through interleukin-9 induction

1 reference

12 December 2020

Expression cloning of the murine and human interleukin 9 receptor cDNAs

1 reference

12 December 2020

Cytokines, chemokines, and cytokine receptors in human microglia

1 reference

12 December 2020

Expression cloning of cDNA encoding a novel human hematopoietic growth factor: human homologue of murine T-cell growth factor P40

1 reference

12 December 2020

Activation of the IL-4 STAT pathway in rheumatoid synovium

1 reference

12 December 2020

10.1007/S11481-009-9186-Y

Identifiers

DOI

1 reference

21 August 2017

1 reference

PubMed ID

20020328