Shiga toxins--from cell biology to biomedical applications (Q37659792)

21 August 2017

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title

Shiga toxins--from cell biology to biomedical applications (English)

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21 August 2017

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Ludger Johannes

1

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PubMed ID

20023663

21 August 2017

Winfried Römer

series ordinal

2

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PubMed ID

20023663

21 August 2017

language of work or name

English

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publication date

21 December 2009

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Nature Reviews Microbiology

21 August 2017

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21 August 2017

8

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21 August 2017

2

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21 August 2017

105-116

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https://scigraph.springernature.com/pub.10.1038/nrmicro2279

21 August 2017

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cites work

Iron regulation of Shiga-like toxin expression in Escherichia coli is mediated by the fur locus

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

Toxin genotypes and plasmid profiles as determinants of systemic sequelae in Escherichia coli O157:H7 infections

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

Susceptibility to hemolytic-uremic syndrome relates to erythrocyte glycosphingolipid patterns

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

Targeting of Shiga toxin B-subunit to retrograde transport route in association with detergent-resistant membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

Ribotoxic stress response: activation of the stress-activated protein kinase JNK1 by inhibitors of the peptidyl transferase reaction and by sequence-specific RNA damage to the alpha-sarcin/ricin loop in the 28S rRNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

Verotoxin-1 stimulation of macrophage-like THP-1 cells up-regulates tissue factor expression through activation of c-Yes tyrosine kinase: Possible signal transduction in tissue factor up-regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

The B Subunit of Shiga Toxin Fused to a Tumor Antigen Elicits CTL and Targets Dendritic Cells to Allow MHC Class I-Restricted Presentation of Peptides Derived from Exogenous Antigens

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

B subunit of Shiga toxin-based vaccines synergize with alpha-galactosylceramide to break tolerance against self antigen and elicit antiviral immunity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

In vitro assessment of a chemically synthesized Shiga toxin receptor analog attached to chromosorb P (Synsorb Pk) as a specific absorbing agent of Shiga toxin 1 and 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

Shiga-like toxin-converting phages from Escherichia coli strains that cause hemorrhagic colitis or infantile diarrhea.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

Sporadic cases of haemolytic-uraemic syndrome associated with faecal cytotoxin and cytotoxin-producing Escherichia coli in stools

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

Nucleotide sequence analysis of the structural genes for Shiga-like toxin I encoded by bacteriophage 933J from Escherichia coli

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

Structural analysis of phage-borne stx genes and their flanking sequences in shiga toxin-producing Escherichia coli and Shigella dysenteriae type 1 strains

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

Shiga toxin-encoding bacteriophages--genomes in motion

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

Functional and genetic analysis of regulatory regions of coliphage H-19B: location of shiga-like toxin and lysis genes suggest a role for phage functions in toxin release.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

The operator and early promoter region of the Shiga toxin type 2-encoding bacteriophage 933W and control of toxin expression

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

Bacteriophage control of Shiga toxin 1 production and release by Escherichia coli.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

Human neutrophils and their products induce Shiga toxin production by enterohemorrhagic Escherichia coli

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

Pathogenesis of Shiga toxin-associated hemolytic uremic syndrome.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

Role of verotoxin receptors in pathogenesis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

Escherichia coli O157:H7 strains that express Shiga toxin (Stx) 2 alone are more neurotropic for gnotobiotic piglets than are isotypes producing only Stx1 or both Stx1 and Stx2.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

Acute renal failure in children: prognostic features after treatment with acute dialysis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

Crystal structure of the holotoxin from Shigella dysenteriae at 2.5 A resolution

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

Crystal structure of the cell-binding B oligomer of verotoxin-1 from E. coli

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

Mechanism of toxin secretion by Vibrio cholerae investigated in strains harboring plasmids that encode heat-labile enterotoxins of Escherichia coli

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

Site of action of a Vero toxin (VT2) from Escherichia coli O157:H7 and of Shiga toxin on eukaryotic ribosomes. RNA N-glycosidase activity of the toxins.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

Cytotoxicity of Shigella dysenteriae 1 for cultured mammalian cells.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

Shiga toxin attacks bacterial ribosomes as effectively as eucaryotic ribosomes.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

Pathogenesis of shigella diarrhea. XI. Isolation of a shigella toxin-binding glycolipid from rabbit jejunum and HeLa cells and its identification as globotriaosylceramide

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

Induction of verotoxin sensitivity in receptor-deficient cell lines using the receptor glycolipid globotriosylceramide

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

Isolation and characterization of functional Shiga toxin subunits and renatured holotoxin

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

Modelling of the interaction of verotoxin-1 (VT1) with its glycolipid receptor, globotriaosylceramide (Gb3)

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

Two distinct binding sites for globotriaosyl ceramide on verotoxins: identification by molecular modelling and confirmation using deoxy analogues and a new glycolipid receptor for all verotoxins.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

Localization of the binding site for modified Gb3 on verotoxin 1 using fluorescence analysis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

Structure of the shiga-like toxin I B-pentamer complexed with an analogue of its receptor Gb3

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

The identification of three biologically relevant globotriaosyl ceramide receptor binding sites on the Verotoxin 1 B subunit

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

A mutational analysis of the globotriaosylceramide-binding sites of verotoxin VT1.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

Solution structure of the complex between the B-subunit homopentamer of verotoxin VT-1 from Escherichia coli and the trisaccharide moiety of globotriaosylceramide.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

Interaction of the Shiga-like toxin type 1 B-subunit with its carbohydrate receptor

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRMICRO2279

Binding of verocytotoxin 1 to its receptor is influenced by differences in receptor fatty acid content

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRMICRO2279

Effect of globotriaosyl ceramide fatty acid alpha-hydroxylation on the binding by verotoxin 1 and verotoxin 2.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

Influence of phospholipid chain length on verotoxin/globotriaosyl ceramide binding in model membranes: comparison of a supported bilayer film and liposomes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

Lipid modulation of glycolipid receptor function. Availability of Gal(alpha 1-4)Gal disaccharide for verotoxin binding in natural and synthetic glycolipids

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

Fatty acid-dependent globotriaosyl ceramide receptor function in detergent resistant model membranes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

Kinetic analysis of binding between Shiga toxin and receptor glycolipid Gb3Cer by surface plasmon resonance

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

Retrograde transport from endosomes to the trans-Golgi network

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

Protein toxins: intracellular trafficking for targeted therapy.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

Tracing the retrograde route in protein trafficking.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

Delivery into cells: lessons learned from plant and bacterial toxins

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

Measuring Retrograde Transport to theTrans-Golgi Network

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

Endocytosis from coated pits of Shiga toxin: a glycolipid-binding protein from Shigella dysenteriae 1.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

Efficient endosome-to-Golgi transport of Shiga toxin is dependent on dynamin and clathrin

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

Rapid cycling of lipid raft markers between the cell surface and Golgi complex

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

Clathrin adaptor epsinR is required for retrograde sorting on early endosomal membranes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

Shiga toxin induces tubular membrane invaginations for its uptake into cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

Retrograde transport of endocytosed Shiga toxin to the endoplasmic reticulum

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

Direct pathway from early/recycling endosomes to the Golgi apparatus revealed through the study of shiga toxin B-fragment transport

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

Rab9 functions in transport between late endosomes and the trans Golgi network

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

The retromer component sorting nexin-1 is required for efficient retrograde transport of Shiga toxin from early endosome to the trans Golgi network.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

The retromer complex and clathrin define an early endosomal retrograde exit site.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

SNX1 and SNX2 mediate retrograde transport of Shiga toxin

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

Evidence for a COP-I-independent transport route from the Golgi complex to the endoplasmic reticulum

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

Passage through the Golgi is necessary for Shiga toxin B subunit to reach the endoplasmic reticulum

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

Furin-induced cleavage and activation of Shiga toxin.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

Structural requirements for furin-induced cleavage and activation of Shiga toxin

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

Proteolytic cleavage of the A subunit is essential for maximal cytotoxicity of Escherichia coli O157:H7 Shiga-like toxin-1

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

Shiga toxin B-subunit binds to the chaperone BiP and the nucleolar protein B23.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

A role for the protease-sensitive loop region of Shiga-like toxin 1 in the retrotranslocation of its A1 domain from the endoplasmic reticulum lumen

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

Shiga toxin is transported from the endoplasmic reticulum following interaction with the luminal chaperone HEDJ/ERdj3.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

A subset of chaperones and folding enzymes form multiprotein complexes in endoplasmic reticulum to bind nascent proteins

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

Membrane cytosolic translocation of verotoxin A1 subunit in target cells.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

Ricin A chain insertion into endoplasmic reticulum membranes is triggered by a temperature increase to 37 {degrees}C

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

Accumulating evidence suggests that several AB-toxins subvert the endoplasmic reticulum-associated protein degradation pathway to enter target cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

The low lysine content of ricin A chain reduces the risk of proteolytic degradation after translocation from the endoplasmic reticulum to the cytosol

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

Dependence of ricin toxicity on translocation of the toxin A-chain from the endoplasmic reticulum to the cytosol

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

Pathogenesis of Shiga toxin-induced hemolytic uremic syndrome

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

Human colorectal tumors and metastases express Gb3 and can be targeted by an intestinal pathogen-based delivery tool

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

Shiga toxin activates p38 MAP kinase through cellular Ca(2+) increase in Vero cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

ZAK: a MAP3Kinase that transduces Shiga toxin- and ricin-induced proinflammatory cytokine expression.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

Shiga toxin 1 triggers a ribotoxic stress response leading to p38 and JNK activation and induction of apoptosis in intestinal epithelial cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

Shiga toxin regulates its entry in a Syk-dependent manner

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

Activation of Src family kinase yes induced by Shiga toxin binding to globotriaosyl ceramide (Gb3/CD77) in low density, detergent-insoluble microdomains

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

Globotriaosyl ceramide (CD77/Gb3) in the glycolipid-enriched membrane domain participates in B-cell receptor–mediated apoptosis by regulating Lyn kinase activity in human B cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

Protein kinase Cdelta is activated by Shiga toxin and regulates its transport.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

An association of 27- and 40-kDa molecules with glycolipids that bind A-B bacterial enterotoxins to cultured cells.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

Shiga toxin facilitates its retrograde transport by modifying microtubule dynamics.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

Shiga toxin binding to globotriaosyl ceramide induces intracellular signals that mediate cytoskeleton remodeling in human renal carcinoma-derived cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

Regulation of proinflammatory cytokine expression by Shiga toxin 1 and/or lipopolysaccharides in the human monocytic cell line THP-1

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

Tumor necrosis factor alpha increases human cerebral endothelial cell Gb3 and sensitivity to Shiga toxin

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

p38 mitogen-activated protein kinase mediates lipopolysaccharide and tumor necrosis factor alpha induction of shiga toxin 2 sensitivity in human umbilical vein endothelial cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

Inhibition of p38 mitogen-activated protein kinase ameliorates cytokine up-regulated shigatoxin-1 toxicity in human brain microvascular endothelial cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

Induction of cytokines in a human colon epithelial cell line by Shiga toxin 1 (Stx1) and Stx2 but not by non-toxic mutant Stx1 which lacks N-glycosidase activity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

Verotoxin activates mitogen-activated protein kinase in human peripheral blood monocytes: role in apoptosis and proinflammatory cytokine release.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

Shiga toxin 1-induced cytokine production is mediated by MAP kinase pathways and translation initiation factor eIF4E in the macrophage-like THP-1 cell line

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

Shiga toxin 1 induces apoptosis through the endoplasmic reticulum stress response in human monocytic cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

Shiga toxin 1 induces apoptosis in the human myelogenous leukemia cell line THP-1 by a caspase-8-dependent, tumor necrosis factor receptor-independent mechanism

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

Rapid Apoptosis Induced by Shiga Toxin in HeLa Cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

Shiga toxin 2 causes apoptosis in human brain microvascular endothelial cells via C/EBP homologous protein

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

Escherichia coli Shiga toxins induce apoptosis in epithelial cells that is regulated by the Bcl-2 family

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

Shiga toxin induces decreased expression of the anti-apoptotic protein Mcl-1 concomitant with the onset of endothelial apoptosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

Two distinct Gb3/CD77 signaling pathways leading to apoptosis are triggered by anti-Gb3/CD77 mAb and verotoxin-1.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

Comparison of ribosome-inactivating proteins in the induction of apoptosis.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

Glycosphingolipid antigens and cancer therapy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

The glycosphingolipid globotriaosylceramide in the metastatic transformation of colon cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

Expression of verotoxin-1 receptor Gb3 in breast cancer tissue and verotoxin-1 signal transduction to apoptosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

Monoclonal antibody against a Burkitt lymphoma-associated antigen

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

The bacterial colicin active against tumor cells in vitro and in vivo is verotoxin 1

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

Verotoxin sensitivity of ECV304 cells in vitro and in vivo in a xenograft tumour model: VT1 as a tumour neovascular marker

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

Verotoxin induces rapid elimination of human renal tumor xenografts in SCID mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

The treatment of malignant meningioma with verotoxin

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

In vivo tumor targeting using a novel intestinal pathogen-based delivery approach.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

Shiga toxin-mediated retrograde delivery of a topoisomerase I inhibitor prodrug.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

Synthesis and properties of a mitochondrial peripheral benzodiazepine receptor conjugate.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

Retrograde delivery of photosensitizer (TPPp-O-beta-GluOH)3 selectively potentiates its photodynamic activity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

Shiga-like toxin subunit B (SLTB)-enhanced delivery of chlorin e6 (Ce6) improves cell killing

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

The B subunit of Shiga toxin coupled to full-size antigenic protein elicits humoral and cell-mediated immune responses associated with a Th1-dominant polarization

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

1st class ticket to class I: protein toxins as pathfinders for antigen presentation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

The Shiga toxin B-subunit targets antigen in vivo to dendritic cells and elicits anti-tumor immunity.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

Shiga toxin as a bacterial defense against a eukaryotic predator, Tetrahymena thermophila

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

Grazing protozoa and the evolution of the Escherichia coli O157:H7 Shiga toxin-encoding prophage.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

Risk factors for the progression of Escherichia coli O157:H7 enteritis to hemolytic-uremic syndrome

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

Randomized, controlled trial of antibiotic therapy for Escherichia coli O157:H7 enteritis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

Effect of subinhibitory concentrations of antibiotics on extracellular Shiga-like toxin I.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

Shiga-like toxins are neutralized by tailored multivalent carbohydrate ligands

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

Assessment in mice of the therapeutic potential of tailored, multivalent Shiga toxin carbohydrate ligands

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

In vivo supramolecular templating enhances the activity of multivalent ligands: a potential therapeutic against the Escherichia coli O157 AB5 toxins

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

Effect of an oral Shiga toxin-binding agent on diarrhea-associated hemolytic uremic syndrome in children: a randomized controlled trial

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

A therapeutic agent with oriented carbohydrates for treatment of infections by Shiga toxin-producing Escherichia coli O157:H7.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

Oral therapeutic agents with highly clustered globotriose for treatment of Shiga toxigenic Escherichia coli infections.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

A new biological agent for treatment of Shiga toxigenic Escherichia coli infections and dysentery in humans

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

Refinement of a therapeutic Shiga toxin-binding probiotic for human trials

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

Production and characterization of protective human antibodies against Shiga toxin 1

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

Human Stx2-specific monoclonal antibodies prevent systemic complications of Escherichia coli O157:H7 infection

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

Structure-based design and characterization of novel platforms for ricin and shiga toxin inhibition

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

Exo1: a new chemical inhibitor of the exocytic pathway

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

Retrograde transport of cholera toxin from the plasma membrane to the endoplasmic reticulum requires the trans-Golgi network but not the Golgi apparatus in Exo2-treated cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

The secretion inhibitor Exo2 perturbs trafficking of Shiga toxin between endosomes and the trans-Golgi network.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

Identification and characterization of small molecules that inhibit intracellular toxin transport

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

Golgicide A reveals essential roles for GBF1 in Golgi assembly and function

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2279

Differentiation-associated toxin receptor modulation, cytokine production, and sensitivity to Shiga-like toxins in human monocytes and monocytic cell lines.

31 March 2020

1 reference

12 December 2020

Shiga toxin-associated hemolytic-uremic syndrome: combined cytotoxic effects of Shiga toxin, interleukin-1 beta, and tumor necrosis factor alpha on human vascular endothelial cells in vitro

1 reference

12 December 2020

Shiga-toxin-producing Escherichia coli and haemolytic uraemic syndrome

1 reference

12 December 2020

Glycosphingolipid receptor function is modified by fatty acid content. Verotoxin 1 and verotoxin 2c preferentially recognize different globotriaosyl ceramide fatty acid homologues

1 reference

12 December 2020

Associations between virulence factors of Shiga toxin-producing Escherichia coli and disease in humans

1 reference

12 December 2020

Vero response to a cytotoxin of Escherichia coli

1 reference

12 December 2020

Expression of the verotoxin receptor glycolipid, globotriaosylceramide, in ovarian hyperplasias.

1 reference

12 December 2020

Shiga toxins stimulate secretion of interleukin-8 from intestinal epithelial cells

1 reference

12 December 2020

Shigella dysenteriae 1 cytotoxin: periplasmic protein releasable by polymyxin B and osmotic shock.

1 reference

12 December 2020

Bcl-2 antiapoptotic protein mediates verotoxin II-induced cell death: possible association between bcl-2 and tissue failure by E. coli O157:H7.

1 reference

12 December 2020

Caspase-3 activation and apoptosis induction coupled with the retrograde transport of shiga toxin: inhibition by brefeldin A.

1 reference

12 December 2020

Subunit structure of Shigella cytotoxin.

1 reference

12 December 2020

Shiga toxin 1-induced activation of c-Jun NH(2)-terminal kinase and p38 in the human monocytic cell line THP-1: possible involvement in the production of TNF-alpha.

1 reference

12 December 2020

Preparation of VT1 and VT2 hybrid toxins from their purified dissociated subunits. Evidence for B subunit modulation of a subunit function

1 reference

12 December 2020

Shiga-like toxin purges human lymphoma from bone marrow of severe combined immunodeficient mice

1 reference

12 December 2020

Shiga and Shiga-like toxins

1 reference

12 December 2020

Shiga toxin, Shiga-like toxin II variant, and ricin are all single-site RNA N-glycosidases of 28 S RNA when microinjected into Xenopus oocytes

1 reference

12 December 2020

Role of lipid rafts in Shiga toxin 1 interaction with the apical surface of Caco-2 cells.

1 reference

12 December 2020

Pathogenesis of Shigella diarrhea: rabbit intestinal cell microvillus membrane binding site for Shigella toxin

1 reference

12 December 2020

Identification of the carbohydrate receptor for Shiga toxin produced by Shigella dysenteriae type 1.

1 reference

12 December 2020

Shiga toxin B-subunit as a tool to study retrograde transport

1 reference

12 December 2020

In vivo tumor targeting by the B-subunit of shiga toxin

1 reference

12 December 2020

Comparison of the relative toxicities of Shiga-like toxins type I and type II for mice

1 reference

12 December 2020

Shiga-like toxin-1 receptor on human breast cancer, lymphoma, and myeloma and absence from CD34(+) hematopoietic stem cells: implications for ex vivo tumor purging and autologous stem cell transplantation.

1 reference

12 December 2020

Major histocompatibility complex class I presentation of exogenous soluble tumor antigen fused to the B-fragment of Shiga toxin

1 reference

12 December 2020

Identifiers

DOI

10.1038/NRMICRO2279

1 reference

21 August 2017

1 reference

PubMed ID

20023663