Endothelial dysfunction: a strategic target in the treatment of hypertension? (Q37686221)

22 August 2017

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title

Endothelial dysfunction: a strategic target in the treatment of hypertension? (English)

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Paul Michel Georges Remi Vanhoutte

22 August 2017

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arterial hypertension

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author

series ordinal

2

object named as

Paul M Vanhoutte

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22 August 2017

Eva H C Tang

1

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22 August 2017

2 February 2010

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22 August 2017

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22 August 2017

459

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22 August 2017

6

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22 August 2017

995-1004

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https://scigraph.springernature.com/pub.10.1007/s00424-010-0786-4

22 August 2017

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Thromboxane A2 receptor antagonists inhibit endothelium-dependent contractions

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Endothelium-derived hyperpolarizing factor: where are we now?

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High glucose via peroxynitrite causes tyrosine nitration and inactivation of prostacyclin synthase that is associated with thromboxane/prostaglandin H(2) receptor-mediated apoptosis and adhesion molecule expression in cultured human aortic endotheli

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Third-generation beta-blockers stimulate nitric oxide release from endothelial cells through ATP efflux: a novel mechanism for antihypertensive action

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Systemic endothelial dysfunction is related to the extent and severity of coronary artery disease.

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Antioxidant effects and the therapeutic mode of action of calcium channel blockers in hypertension and atherosclerosis

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12 December 2020

Hypertension and the absence of EDHF-mediated responses favour endothelium-dependent contractions in renal arteries of the rat.

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12 December 2020

The calcium channel blocker amlodipine promotes the unclamping of eNOS from caveolin in endothelial cells.

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Contractions to oxygen-derived free radicals are augmented in aorta of the spontaneously hypertensive rat.

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Endothelium-dependent contractions are associated with both augmented expression of prostaglandin H synthase-1 and hypersensitivity to prostaglandin H2 in the SHR aorta

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12 December 2020

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Epoxyeicosatrienoic acids function as selective, endogenous antagonists of native thromboxane receptors: identification of a novel mechanism of vasodilation

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12 December 2020

Endothelin-1 releases endothelium-derived endoperoxides and thromboxane A2 in porcine coronary arteries with regenerated endothelium

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12 December 2020

Endothelium-dependent contractions occur in the aorta of wild-type and COX2-/- knockout but not COX1-/- knockout mice

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12 December 2020

Prostaglandin H2 may be the endothelium-derived contracting factor released by acetylcholine in the aorta of the rat

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12 December 2020

Mechanisms of hydrogen peroxide-induced contraction of rat aorta

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12 December 2020

Impairment of endothelium-dependent vasorelaxation in chronic two-kidney, one clip hypertensive rats.

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12 December 2020

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12 December 2020

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12 December 2020

Cyclooxygenase-2-derived prostaglandin F2alpha mediates endothelium-dependent contractions in the aortae of hamsters with increased impact during aging

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12 December 2020

Angiotensin II-induced superoxide anion generation in human vascular endothelial cells: role of membrane-bound NADH-/NADPH-oxidases

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12 December 2020

Nitric oxide the gatekeeper of endothelial vasomotor control

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12 December 2020

The role of prostacyclin in vascular tissue

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12 December 2020

Nitroglycerin-induced S-nitrosylation and desensitization of soluble guanylyl cyclase contribute to nitrate tolerance

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12 December 2020

Contractions to endothelin in normotensive and spontaneously hypertensive rats: role of endothelium and prostaglandins

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12 December 2020

The role of prostaglandin E and thromboxane-prostanoid receptors in the response to prostaglandin E2 in the aorta of Wistar Kyoto rats and spontaneously hypertensive rats

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12 December 2020

Endothelium-dependent contractions and endothelial dysfunction in human hypertension

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12 December 2020

Superoxide anion is an endothelium-derived contracting factor

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12 December 2020

Hydrogen peroxide is an endothelium-dependent contracting factor in rat renal artery

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12 December 2020

Abnormal endothelium-dependent vascular relaxation in patients with essential hypertension

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12 December 2020

Mechanisms of hydroxyl radical-induced contraction of rat aorta

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12 December 2020

The effects of sustained-release-L-arginine formulation on blood pressure and vascular compliance in 29 healthy individuals.

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12 December 2020

Angiotensin-converting enzyme inhibition with quinapril improves endothelial vasomotor dysfunction in patients with coronary artery disease. The TREND (Trial on Reversing ENdothelial Dysfunction) Study

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12 December 2020

Uridine adenosine tetraphosphate: a novel endothelium- derived vasoconstrictive factor

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12 December 2020

Oral L-arginine improves endothelial dysfunction in patients with essential hypertension

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12 December 2020

Contractile responses elicited by hydrogen peroxide in aorta from normotensive and hypertensive rats. Endothelial modulation and mechanism involved

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12 December 2020

Oxygen-derived free radicals mediate endothelium-dependent contractions to acetylcholine in aortas from spontaneously hypertensive rats

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12 December 2020

Prostanoids and reactive oxygen species: team players in endothelium-dependent contractions

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12 December 2020

Altered gene expression of prostacyclin synthase and prostacyclin receptor in the thoracic aorta of spontaneously hypertensive rats

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12 December 2020

Superoxide anion is involved in the breakdown of endothelium-derived vascular relaxing factor

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12 December 2020

Effects of antihypertensive drugs on endothelial dysfunction: clinical implications

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12 December 2020

In SHR aorta, calcium ionophore A-23187 releases prostacyclin and thromboxane A2 as endothelium-derived contracting factors

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12 December 2020

Amlodipine activates the endothelial nitric oxide synthase by altering phosphorylation on Ser1177 and Thr495.

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12 December 2020

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12 December 2020

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12 December 2020

Vascular endothelial dysfunction: does tetrahydrobiopterin play a role?

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12 December 2020

The calcium ionophore A23187 induces endothelium-dependent contractions in femoral arteries from rats with streptozotocin-induced diabetes.

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12 December 2020

Role of prostaglandins in acetylcholine-induced contraction of aorta from spontaneously hypertensive and Wistar-Kyoto rats

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12 December 2020

Endothelium-dependent contractions to acetylcholine, ATP and the calcium ionophore A 23187 in aortas from spontaneously hypertensive and normotensive rats

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12 December 2020

Nitric oxide and inactivation of the endothelium-dependent contracting factor released by acetylcholine in spontaneously hypertensive rat.

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12 December 2020

Tetrahydrobiopterin, superoxide, and vascular dysfunction

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12 December 2020

Acetylcholine-induced endothelium-dependent contractions in the SHR aorta: the Janus face of prostacyclin

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12 December 2020

Endothelium-derived contracting factor in carotid artery of hypertensive Dahl rats

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12 December 2020

Central role of mitochondrial aldehyde dehydrogenase and reactive oxygen species in nitroglycerin tolerance and cross-tolerance.

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12 December 2020

Endothelial dysfunction and vascular disease

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12 December 2020

L-Arginine improves endothelial function in renal artery of hypertensive Dahl rats

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12 December 2020

Acetylcholine and sodium nitroprusside cause long-term inhibition of EDCF-mediated contractions

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12 December 2020

Tetrahydrobiopterin enhances forearm vascular response to acetylcholine in both normotensive and hypertensive individuals

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12 December 2020

Inflammation and the metabolic syndrome: role of angiotensin II and oxidative stress

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12 December 2020

Vasodilation to acetylcholine in primary and secondary forms of human hypertension

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12 December 2020

Blunted acetylcholine relaxation and nitric oxide release in arteries from renal hypertensive rats

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12 December 2020

Two isoforms of cyclooxygenase contribute to augmented endothelium-dependent contractions in femoral arteries of 1-year-old rats

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12 December 2020

Responses to endothelium-derived factors and their interaction in mesenteric arteries from Wistar-Kyoto and stroke-prone spontaneously hypertensive rats

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12 December 2020

Gap junction inhibitors reduce endothelium-dependent contractions in the aorta of spontaneously hypertensive rats

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12 December 2020

Calcium and reactive oxygen species increase in endothelial cells in response to releasers of endothelium-derived contracting factor

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12 December 2020

10.1007/S00424-010-0786-4

Identifiers

DOI

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22 August 2017

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PubMed ID

20127126