Calyculins and related marine natural products as serine-threonine protein phosphatase PP1 and PP2A inhibitors and total syntheses of calyculin A, B, and C. (Q37693760)

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scientific article published on 21 January 2010

Language	Label	Description	Also known as
English	Calyculins and related marine natural products as serine-threonine protein phosphatase PP1 and PP2A inhibitors and total syntheses of calyculin A, B, and C.	scientific article published on 21 January 2010

Statements

scholarly article

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20161975%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

3 references

Europe PubMed Central

18 January 2021

20 January 2021

Calyculins and related marine natural products as serine-threonine protein phosphatase PP1 and PP2A inhibitors and total syntheses of calyculin A, B, and C (English)

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20161975%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

1 reference

28 September 2019

mechanism of action

1 reference

2 October 2019

organic compound, having C-P covalent bound

1 reference

12 November 2019

1 reference

20 November 2019

1 reference

18 January 2021

enzyme inhibitor

1 reference

20 January 2021

marine natural product

0 references

natural product

1 reference

based on heuristic

inferred from title

3

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20161975%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

author name string

Annika E Fagerholm

1

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20161975%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Damien Habrant

2

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20161975%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

publication date

21 January 2010

7 references

28 September 2019

2 October 2019

12 November 2019

20 November 2019

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20161975%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

18 January 2021

20 January 2021

7 references

28 September 2019

2 October 2019

12 November 2019

20 November 2019

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20161975%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

18 January 2021

20 January 2021

8

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20161975%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

1

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20161975%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

122-172

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20161975%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

copyright license

Creative Commons Attribution 3.0 Unported

6 references

Europe PubMed Central

28 September 2019

Europe PubMed Central

2 October 2019

Europe PubMed Central

12 November 2019

Europe PubMed Central

20 November 2019

Europe PubMed Central

18 January 2021

Europe PubMed Central

20 January 2021

copyright status

0 references

Highly regio- and stereoselective synthesis of (Z)-trisubstituted alkenes via propyne bromoboration and tandem Pd-catalyzed cross-coupling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817927

23 August 2017

Enzyme inhibitors from marine invertebrates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817927

23 August 2017

Crystal structure of the complex between calyculin A and the catalytic subunit of protein phosphatase 1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817927

23 August 2017

Serine-threonine protein phosphatase inhibitors: development of potential therapeutic strategies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817927

23 August 2017

Role of serine/threonine protein phosphatase 2A in cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817927

23 August 2017

Protein phosphatase 2A: the Trojan Horse of cellular signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817927

23 August 2017

The structure and mechanism of protein phosphatases: insights into catalysis and regulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817927

23 August 2017

Novel protein serine/threonine phosphatases: variety is the spice of life

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817927

23 August 2017

Three-dimensional structure of the catalytic subunit of protein serine/threonine phosphatase-1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817927

23 August 2017

Swinhoeiamide A, a new highly active calyculin derivative from the marine sponge Theonella swinhoei

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817927

23 June 2018

A model for binding of structurally diverse natural product inhibitors of protein phosphatases PP1 and PP2A.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817927

23 June 2018

A molecular modeling analysis of the binding interactions between the okadaic acid class of natural product inhibitors and the Ser-Thr phosphatases, PP1 and PP2A.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817927

23 June 2018

Inhibition of the Ser-Thr phosphatases PP1 and PP2A by naturally occurring toxins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817927

23 June 2018

Inhibition of specific binding of okadaic acid to protein phosphatase 2A by microcystin-LR, calyculin-A and tautomycin: method of analysis of interactions of tight-binding ligands with target protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817927

23 June 2018

Stereochemistry of the allylation and crotylation reactions of alpha-methyl-beta-hydroxy aldehydes with allyl- and crotyltrifluorosilanes. Synthesis of anti,anti-dipropionate stereotriads and stereodivergent pathways for the reactions with 2,3-anti-

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817927

1 September 2018

A new cytotoxic calyculinamide derivative, geometricin A, from the Australian sponge Luffariella geometrica

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817927

1 September 2018

Asymmetric Synthesis of Calyculin C. 2. Synthesis of the C(26)-C(37) Fragment and Model Wittig Couplings

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817927

1 September 2018

Asymmetric Synthesis of Calyculin C. 1. Synthesis of the C(1)-C(25) Fragment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817927

1 September 2018

A study of the binding requirements of calyculin A and dephosphonocalyculin A with PP1, development of a molecular recognition model for the binding interactions of the okadaic acid class of compounds with PP1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817927

1 September 2018

The binding mode of calyculin A to protein phosphatase-1. A novel spiroketal vector model.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817927

1 September 2018

The Synthesis of Naturally Occurring()-Calyculin A

1 reference

https://api.crossref.org/works/10.3390%2FMD80100122

21 January 2018

Inhibition of protein phosphatase-1 by clavosines A and B. Novel members of the calyculin family of toxins

1 reference

https://pubmed.ncbi.nlm.nih.gov/20161975

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isolation of Calyculins, Calyculinamides, and Swinholide H from the New Zealand Deep-Water Marine Sponge Lamellomorpha strongylata

1 reference

https://pubmed.ncbi.nlm.nih.gov/20161975

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isolation of Four New Calyculins from the Marine Sponge Discodermia calyx(1)

1 reference

https://pubmed.ncbi.nlm.nih.gov/20161975

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synthesis of the C(26)-C(32) Oxazole Fragment of Calyculin C: A Test Case for Oxazole Syntheses

1 reference

https://pubmed.ncbi.nlm.nih.gov/20161975

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insight into binding of calyculin A to protein phosphatase 1: isolation of hemicalyculin a and chemical transformation of calyculin A

1 reference

https://pubmed.ncbi.nlm.nih.gov/20161975

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lithistid Sponges: Star Performers or Hosts to the Stars

1 reference

https://pubmed.ncbi.nlm.nih.gov/20161975

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A molecular basis for different interactions of marine toxins with protein phosphatase-1. Molecular models for bound motuporin, microcystins, okadaic acid, and calyculin A

1 reference

https://pubmed.ncbi.nlm.nih.gov/20161975

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.3390/MD80100122

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20161975%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20161975%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20161975%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

ResearchGate publication ID

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