Differential roles of PI3-kinase and Kit tyrosine 821 in Kit receptor-mediated proliferation, survival and cell adhesion in mast cells. (Q37693932)

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20 October 2019

title

Differential roles of PI3-kinase and Kit tyrosine 821 in Kit receptor-mediated proliferation, survival and cell adhesion in mast cells (English)

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20 October 2019

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1 reference

4

L Sepp-Lorenzino

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20 October 2019

author name string

H Serve

1

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20 October 2019

N S Yee

2

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20 October 2019

G Stella

3

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20 October 2019

J C Tan

5

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20 October 2019

P Besmer

6

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language of work or name

English

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publication date

1 February 1995

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20 October 2019

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20 October 2019

volume

14

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issue

3

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20 October 2019

page(s)

473-483

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Complexes of Ras.GTP with Raf-1 and mitogen-activated protein kinase kinase

20 October 2019

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23 August 2017

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23 August 2017

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23 August 2017

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Role of kit-ligand in proliferation and suppression of apoptosis in mast cells: basis for radiosensitivity of white spotting and steel mutant mice

23 August 2017

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Tyrosine residue 719 of the c-kit receptor is essential for binding of the P85 subunit of phosphatidylinositol (PI) 3-kinase and for c-kit-associated PI 3-kinase activity in COS-1 cells

23 August 2017

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Expression of the Kit and KitA receptor isoforms in human acute myelogenous leukemia

23 August 2017

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Inhibition of histamine secretion by wortmannin through the blockade of phosphatidylinositol 3-kinase in RBL-2H3 cells.

23 August 2017

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23 August 2017

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Autophosphorylation of the PDGF receptor in the kinase insert region regulates interactions with cell proteins

23 August 2017

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The proto-oncogene c-kit encoding a transmembrane tyrosine kinase receptor maps to the mouse W locus

23 August 2017

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Primary structure of c-kit: relationship with the CSF-1/PDGF receptor kinase family--oncogenic activation of v-kit involves deletion of extracellular domain and C terminus.

23 August 2017

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Human proto-oncogene c-kit: a new cell surface receptor tyrosine kinase for an unidentified ligand

23 August 2017

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A point mutation at tyrosine-809 in the human colony-stimulating factor 1 receptor impairs mitogenesis without abrogating tyrosine kinase activity, association with phosphatidylinositol 3-kinase, or induction of c-fos and junB genes

23 August 2017

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23 August 2017

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Signal transduction by normal isoforms and W mutant variants of the Kit receptor tyrosine kinase

23 August 2017

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Induction of mast cell proliferation, maturation, and heparin synthesis by the rat c-kit ligand, stem cell factor

23 August 2017

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The Steel/W transduction pathway: kit autophosphorylation and its association with a unique subset of cytoplasmic signaling proteins is induced by the Steel factor.

23 August 2017

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Exon skipping by mutation of an authentic splice site of c-kit gene in W/W mouse

23 August 2017

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A specific combination of substrates is involved in signal transduction by the kit-encoded receptor.

23 August 2017

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Candidate ligand for the c-kit transmembrane kinase receptor: KL, a fibroblast derived growth factor stimulates mast cells and erythroid progenitors

23 August 2017

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The hematopoietic growth factor KL is encoded by the Sl locus and is the ligand of the c-kit receptor, the gene product of the W locus

23 August 2017

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Tyrosine 706 and 807 phosphorylation site mutants in the murine colony-stimulating factor-1 receptor are unaffected in their ability to bind or phosphorylate phosphatidylinositol-3 kinase but show differential defects in their ability to induce earl

23 August 2017

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23 August 2017

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Steel factor stimulates the tyrosine phosphorylation of the proto-oncogene product, p95vav, in human hemopoietic cells

23 August 2017

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The human recombinant c-kit receptor ligand, rhSCF, induces mediator release from human cutaneous mast cells and enhances IgE-dependent mediator release from both skin mast cells and peripheral blood basophils.

23 August 2017

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p21ras activation via hemopoietin receptors and c-kit requires tyrosine kinase activity but not tyrosine phosphorylation of p21ras GTPase-activating protein

23 August 2017

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23 August 2017

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23 August 2017

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The SH2 and SH3 domain-containing protein GRB2 links receptor tyrosine kinases to ras signaling

23 August 2017

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The when and how of Src regulation

23 August 2017

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Mutations of the platelet-derived growth factor receptor that cause a loss of ligand-induced conformational change, subtle changes in kinase activity, and impaired ability to stimulate DNA synthesis

14 September 2017

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14 September 2017

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W-sash affects positive and negative elements controlling c-kit expression: ectopic c-kit expression at sites of kit-ligand expression affects melanogenesis

14 September 2017

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Multiple cytokines induce the tyrosine phosphorylation of Shc and its association with Grb2 in hemopoietic cells

28 September 2017

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Mechanism of kit ligand, phorbol ester, and calcium-induced down-regulation of c-kit receptors in mast cells

23 June 2018

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Steel factor and c-kit regulate cell-matrix adhesion.

23 June 2018

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Stem cell factor induces mast cell adhesion to fibronectin.

23 June 2018

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A new acute transforming feline retrovirus and relationship of its oncogene v-kit with the protein kinase gene family.

23 June 2018

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23 June 2018

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Identification of multiple epidermal growth factor-stimulated protein serine/threonine kinases from Swiss 3T3 cells

23 June 2018

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Mast cell adhesion to fibronectin.

23 June 2018

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A new allele sash (Wsh) at the W-locus and a spontaneous recessive lethal in mice

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12 December 2020

Mast cells in spotted mutant mice (W Ph mi)

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The Dominant W 42 Spotting Phenotype Results from a Missense Mutation in the c- kit Receptor Kinase

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The c-kit receptor ligand functions as a mast cell chemoattractant

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c-kit Gene was not transcribed in cultured mast cells of mast cell-deficient Wsh/Wsh mice that have a normal number of erythrocytes and a normal c-kit coding region

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In a concerted action kit ligand and interleukin 3 control the synthesis of serotonin in murine bone marrow-derived mast cells. Up-regulation of GTP cyclohydrolase I and tryptophan 5-monooxygenase activity by the kit ligand

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Mechanism of down-regulation of c-kit receptor. Roles of receptor tyrosine kinase, phosphatidylinositol 3'-kinase, and protein kinase C

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Competitive repopulation: a new assay for long-term stem cell functional capacity

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10.1002/J.1460-2075.1995.TB07023.X

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20 October 2019

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20 October 2019

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