RAR-specific agonist/antagonists which dissociate transactivation and AP1 transrepression inhibit anchorage-independent cell proliferation. (Q37695128)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7720709%20AND%20SRC:MED&resulttype=core&format=json

24 October 2019

title

RAR-specific agonist/antagonists which dissociate transactivation and AP1 transrepression inhibit anchorage-independent cell proliferation (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7720709%20AND%20SRC:MED&resulttype=core&format=json

24 October 2019

author name string

Chen JY

1

1 reference

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24 October 2019

Penco S

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7720709%20AND%20SRC:MED&resulttype=core&format=json

24 October 2019

Ostrowski J

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7720709%20AND%20SRC:MED&resulttype=core&format=json

24 October 2019

Balaguer P

4

1 reference

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24 October 2019

Pons M

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7720709%20AND%20SRC:MED&resulttype=core&format=json

24 October 2019

Starrett JE

6

1 reference

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24 October 2019

Reczek P

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7720709%20AND%20SRC:MED&resulttype=core&format=json

24 October 2019

Chambon P

8

1 reference

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24 October 2019

Gronemeyer H

9

1 reference

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24 October 2019

language of work or name

English

0 references

publication date

1 March 1995

1 reference

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24 October 2019

1 reference

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24 October 2019

volume

14

1 reference

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24 October 2019

issue

6

1 reference

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24 October 2019

page(s)

1187-1197

1 reference

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PMLRAR homodimers: distinct DNA binding properties and heteromeric interactions with RXR

24 October 2019

cites work

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RARs and RXRs: evidence for two autonomous transactivation functions (AF-1 and AF-2) and heterodimerization in vivo

23 August 2017

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Function of retinoic acid receptor gamma in the mouse

23 August 2017

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Efficient transactivation by retinoic acid receptors in yeast requires retinoid X receptors

23 August 2017

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Retinoic acid receptors and retinoid X receptors: interactions with endogenous retinoic acids

23 August 2017

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Retinoic acid inhibition of IL-1-induced IL-6 production by human lung fibroblasts

23 August 2017

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Blocking of tumor promoter-induced AP-1 activity inhibits induced transformation in JB6 mouse epidermal cells

23 August 2017

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The patterns of binding of RAR, RXR and TR homo- and heterodimers to direct repeats are dictated by the binding specificites of the DNA binding domains.

23 August 2017

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The dimerization interfaces formed between the DNA binding domains of RXR, RAR and TR determine the binding specificity and polarity of the full-length receptors to direct repeats.

23 August 2017

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Dimerization interfaces formed between the DNA binding domains determine the cooperative binding of RXR/RAR and RXR/TR heterodimers to DR5 and DR4 elements

23 August 2017

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Firefly luciferase gene: structure and expression in mammalian cells

23 August 2017

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13-cis-retinoic acid in the treatment of oral leukoplakia

23 August 2017

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Prevention of skin cancer in xeroderma pigmentosum with the use of oral isotretinoin

23 August 2017

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Use of all-trans retinoic acid in the treatment of acute promyelocytic leukemia

23 August 2017

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The yeast UASG is a transcriptional enhancer in human HeLa cells in the presence of the GAL4 trans-activator

23 August 2017

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Contragestion and other clinical applications of RU 486, an antiprogesterone at the receptor

23 August 2017

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Interleukin 6 is expressed in high levels in psoriatic skin and stimulates proliferation of cultured human keratinocytes

23 August 2017

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23 August 2017

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v-Ha-ras transgene abrogates the initiation step in mouse skin tumorigenesis: effects of phorbol esters and retinoic acid

23 August 2017

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On the mechanism for efficient repression of the interleukin-6 promoter by glucocorticoids: enhancer, TATA box, and RNA start site (Inr motif) occlusion

23 August 2017

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All-trans retinoic acid in acute promyelocytic leukemias. II. In vitro studies: structure-function relationship.

23 August 2017

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All-trans retinoic acid as a differentiation therapy for acute promyelocytic leukemia. I. Clinical results

23 August 2017

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Negative regulation of the rat stromelysin gene promoter by retinoic acid is mediated by an AP1 binding site

23 August 2017

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Novel pathway for thyroid hormone receptor action through interaction with jun and fos oncogene activities

23 August 2017

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AIDS Kaposi sarcoma-derived cells produce and respond to interleukin 6

23 August 2017

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RXR beta: a coregulator that enhances binding of retinoic acid, thyroid hormone, and vitamin D receptors to their cognate response elements

23 August 2017

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All-trans retinoic acid modulates the retinoic acid receptor-alpha in promyelocytic cells

23 August 2017

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Retinoic acid is a negative regulator of AP-1-responsive genes.

23 August 2017

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17 beta-estradiol inhibits interleukin-6 production by bone marrow-derived stromal cells and osteoblasts in vitro: a potential mechanism for the antiosteoporotic effect of estrogens

23 August 2017

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Retinoids in cancer prevention and therapy

23 August 2017

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Interleukin-6 and its receptor: a paradigm for cytokines

23 August 2017

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Retinoids selective for retinoid X receptor response pathways

23 August 2017

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Multiplicity generates diversity in the retinoic acid signalling pathways

23 August 2017

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Convergence of 9-cis retinoic acid and peroxisome proliferator signalling pathways through heterodimer formation of their receptors

23 August 2017

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Identification of synthetic retinoids with selectivity for human nuclear retinoic acid receptor gamma

23 August 2017

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A retinoic acid receptor alpha antagonist selectively counteracts retinoic acid effects

23 August 2017

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H-2RIIBP (RXR beta) heterodimerization provides a mechanism for combinatorial diversity in the regulation of retinoic acid and thyroid hormone responsive genes

23 August 2017

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RXR alpha, a promiscuous partner of retinoic acid and thyroid hormone receptors

23 August 2017

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Characterization of three RXR genes that mediate the action of 9-cis retinoic acid

23 August 2017

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9-cis retinoic acid is a high affinity ligand for the retinoid X receptor

23 August 2017

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Purification, cloning, and RXR identity of the HeLa cell factor with which RAR or TR heterodimerizes to bind target sequences efficiently

23 August 2017

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9-Cis retinoic acid stereoisomer binds and activates the nuclear receptor RXRα

23 August 2017

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Structure of the retinoid X receptor alpha DNA binding domain: a helix required for homodimeric DNA binding

23 August 2017

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Multiple parameters control the selectivity of nuclear receptors for their response elements. Selectivity and promiscuity in response element recognition by retinoic acid receptors and retinoid X receptors

6 September 2017

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Down-modulation of interleukin-6 gene expression by 17 beta-estradiol in the absence of high affinity DNA binding by the estrogen receptor

6 September 2017

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Comparative assessment of the toxicology of vitamin A and retinoids in man.

6 September 2017

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Distinct classes of transcriptional activating domains function by different mechanisms

6 September 2017

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Antitumor promotion and antiinflammation: down-modulation of AP-1 (Fos/Jun) activity by glucocorticoid hormone

6 September 2017

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Activation of the ovalbumin gene by the estrogen receptor involves the fos-jun complex

6 September 2017

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A single amino acid that determines the sensitivity of progesterone receptors to RU486.

6 September 2017

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Differential regulation of collagenase gene expression by retinoic acid receptors—α, β and γ

6 September 2017

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Interference between pathway-specific transcription factors: glucocorticoids antagonize phorbol ester-induced AP-1 activity without altering AP-1 site occupation in vivo

6 September 2017

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The retinoid signaling pathway: molecular and genetic analyses

6 September 2017

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14 September 2017

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The contribution of the N- and C-terminal regions of steroid receptors to activation of transcription is both receptor and cell-specific.

14 September 2017

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Nuclear receptor/AP-1 interaction

14 September 2017

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Retinoic acid receptors and cellular retinoid binding proteins: complex interplay in retinoid signaling

28 September 2017

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A distinct modulating domain in glucocorticoid receptor monomers in the repression of activity of the transcription factor AP-1.

28 September 2017

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Differential recognition of target genes by nuclear receptor monomers, dimers, and heterodimers

28 September 2017

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The cellular response to induction of the p21 c-Ha-ras oncoprotein includes stimulation of jun gene expression

28 September 2017

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Cell-specific inhibitory and stimulatory effects of Fos and Jun on transcription activation by nuclear receptors

28 September 2017

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Retinoic acid receptors and cellular retinoid binding proteins. II. Their differential pattern of transcription during early morphogenesis in mouse embryos

28 September 2017

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A new class of retinoids with selective inhibition of AP-1 inhibits proliferation

28 September 2017

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Determinants for selective RAR and TR recognition of direct repeat HREs.

28 September 2017

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Retinoic acid receptors and retinoid X receptor-alpha down-regulate the transforming growth factor-beta 1 promoter by antagonizing AP-1 activity

23 June 2018

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Mechanism of action of a dominant-negative mutant of c-Jun.

23 June 2018

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Functional antagonism between oncoprotein c-Jun and the glucocorticoid receptor

23 June 2018

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Transcriptional interference between c-Jun and the glucocorticoid receptor: mutual inhibition of DNA binding due to direct protein-protein interaction.

23 June 2018

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Specific spatial and temporal distribution of retinoic acid receptor gamma transcripts during mouse embryogenesis

23 June 2018

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Expression of retinoic acid receptor genes and the ligand-binding selectivity of retinoic acid receptors (RAR's).

23 June 2018

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Transcription factor interactions: selectors of positive or negative regulation from a single DNA element.

23 June 2018

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Inhibition of tumor cell growth by retinoids

23 June 2018

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Retinoic acid receptors and cellular retinoid binding proteins. I. A systematic study of their differential pattern of transcription during mouse organogenesis

23 June 2018

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Transformation suppressor activity of a Jun transcription factor lacking its activation domain

23 June 2018

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The retinoic acid alpha receptor gene is frequently disrupted in its 5' part in Chinese patients with acute promyelocytic leukemia

23 June 2018

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Inhibition of Estrogen Receptor Activity by the Tumor Promoter 12-O-Tetradeconylphorbol-13-Acetate: A Molecular Analysis

23 June 2018

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13-cis-Retinoic Acid Plus Interferon -2a: Highly Active Systemic Theraphy for Squamous Cell Carcinoma of the Cervix

23 June 2018

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13-cis-Retinoic Acid and Interferon -2a: Effective Combination. Therapy for Advanced Squamous Cell Carcinoma of the Skin

23 June 2018

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Antagonism between retinoic acid receptors and AP-1: implications for tumor promotion and inflammation

23 June 2018

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Switching agonistic, antagonistic, and mixed transcriptional responses to 11 beta-substituted progestins by mutation of the progesterone receptor

23 June 2018

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Homodimer formation of retinoid X receptor induced by 9-cis retinoic acid

23 June 2018

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Suppression of oncogene-induced transformation by a deletion mutant of c-jun.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=398196

Retinoic acid receptors and cellular retinoid binding proteins. III. Their differential transcript distribution during mouse nervous system development.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=398196

Differential orientations of the DNA-binding domain and carboxy-terminal dimerization interface regulate binding site selection by nuclear receptor heterodimers.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=398196

Developmental expression of murine retinoid X receptor (RXR) genes.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=398196

Ordered binding of retinoic acid and retinoid-X receptors to asymmetric response elements involves determinants adjacent to the DNA-binding domain.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=398196

RXR alpha mutant mice establish a genetic basis for vitamin A signaling in heart morphogenesis.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=398196

Role of retinoids in differentiation and carcinogenesis.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=398196

Molecular evaluation of response to all-trans-retinoic acid therapy in patients with acute promyelocytic leukemia

1 September 2018

1 reference

12 December 2020

Differentiation Therapy of Acute Promyelocytic Leukemia with Tretinoin (All-trans-Retinoic Acid)

1 reference

12 December 2020

Topical treatment of epidemic Kaposi's sarcoma with all-trans-retinoic acid

1 reference

12 December 2020

Increased osteoclast development after estrogen loss: mediation by interleukin-6

1 reference

12 December 2020

Induction of IL-6 gene expression in Kaposi's sarcoma cells

1 reference

12 December 2020

Using examples of firefly luciferase gene for the study of biological activities (estrogens, retinoids, phorbol esters)

1 reference

12 December 2020

Prevention of local relapses and new localisations of oral leukoplakias with the synthetic retinoid fenretinide (4-HPR). Preliminary results

1 reference

12 December 2020

Inhibition by Retinoic Acid of Collagenase Production in Rheumatoid Synovial Cells

1 reference

12 December 2020

An improved radioreceptor assay for 1,25-dihydroxyvitamin D in human plasma

1 reference

12 December 2020

Inflammation and collagenase production in rats with adjuvant arthritis reduced with 13-cis-retinoic acid

1 reference

12 December 2020

Inhibition of both stage I and stage II mouse skin tumour promotion by retinoic acid and the dependence of inhibition of tumor promotion on the duration of retinoic acid treatment

1 reference

12 December 2020

Autocrine generation and requirement of BSF-2/IL-6 for human multiple myelomas

1 reference

12 December 2020

A Harvey-ras responsive transcription element is also responsive to a tumour-promoter and to serum

1 reference

12 December 2020

Excessive production of interleukin 6/B cell stimulatory factor-2 in rheumatoid arthritis

1 reference

12 December 2020

Steroid hormone receptors compete for factors that mediate their enhancer function

1 reference

12 December 2020

Differential expression of genes encoding α, β and γ retinoic acid receptors and CRABP in the developing limbs of the mouse

1 reference

12 December 2020

Prevention of second primary tumors with isotretinoin in squamous-cell carcinoma of the head and neck

1 reference

12 December 2020

Interleukin-1 stimulates and all-trans-retinoic acid inhibits collagenase gene expression through its 5' activator protein-1-binding site

1 reference

12 December 2020

10.1002/J.1460-2075.1995.TB07102.X

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7720709%20AND%20SRC:MED&resulttype=core&format=json

24 October 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7720709%20AND%20SRC:MED&resulttype=core&format=json

24 October 2019

PubMed publication ID

7720709

1 reference