Role of estrogen in hepatocellular carcinoma: is inflammation the key? (Q37710885)

22 August 2017

1 reference

17 November 2019

Role of estrogen in hepatocellular carcinoma: is inflammation the key? (English)

1 reference

22 August 2017

1 reference

PubMed publication ID

24708807

hepatocellular carcinoma

1 reference

17 November 2019

1 reference

17 November 2019

1 reference

17 November 2019

4

Rui Ma

1 reference

22 August 2017

Liang Shi

1

1 reference

22 August 2017

Yili Feng

series ordinal

2

1 reference

22 August 2017

Hui Lin

series ordinal

3

1 reference

22 August 2017

Xiujun Cai

series ordinal

5

1 reference

22 August 2017

language of work or name

1 reference

8 April 2014

3 references

Journal of Translational Medicine

22 August 2017

3 April 2019

17 November 2019

3 references

22 August 2017

3 April 2019

17 November 2019

12

1 reference

22 August 2017

93

1 reference

Creative Commons Attribution 2.0 Generic

22 August 2017

2 references

3 April 2019

on focus list of Wikimedia project

17 November 2019

copyright status

copyrighted

0 references

ScienceSource

0 references

cites work

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23 August 2017

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23 August 2017

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miR-22 inhibits estrogen signaling by directly targeting the estrogen receptor alpha mRNA

23 August 2017

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Role of estrogen in liver cancer

23 August 2017

1 reference

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Role of sex steroid receptors in pathobiology of hepatocellular carcinoma

23 August 2017

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NF-kappaB signaling, liver disease and hepatoprotective agents

23 August 2017

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23 August 2017

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Selective estrogen receptor-beta agonists repress transcription of proinflammatory genes

23 August 2017

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Mechanistic and prognostic significance of aberrant methylation in the molecular pathogenesis of human hepatocellular carcinoma

23 August 2017

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The complex role of estrogens in inflammation.

23 August 2017

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23 August 2017

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Oral contraception and the risk of hepatocellular carcinoma

23 August 2017

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23 August 2017

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Sex hormones and risk of liver tumor.

23 August 2017

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The Expression of Estrogen Receptors in Hepatocellular Carcinoma in Korean Patients

23 August 2017

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The Foxa family of transcription factors in development and metabolism

23 August 2017

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23 August 2017

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Foxa1 and Foxa2 interact with the androgen receptor to regulate prostate and epididymal genes differentially.

23 August 2017

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Macrophages: Obligate Partners for Tumor Cell Migration, Invasion, and Metastasis

23 August 2017

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NF-kappaB: linking inflammation and immunity to cancer development and progression

23 August 2017

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Chromosome-wide mapping of estrogen receptor binding reveals long-range regulation requiring the forkhead protein FoxA1

23 August 2017

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Transcription factor cross-talk: the estrogen receptor and NF-kappaB.

23 August 2017

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Primary liver cancer: worldwide incidence and trends

23 August 2017

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Estrogen receptor beta inhibits 17beta-estradiol-stimulated proliferation of the breast cancer cell line T47D.

23 August 2017

1 reference

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Suppression of the protein tyrosine phosphatase receptor type O gene (PTPRO) by methylation in hepatocellular carcinomas

23 August 2017

1 reference

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Impact of oestrogens on the progression of liver disease

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992128

Estrogens receptors and oxidative damage in the liver

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992128

Sex hormones and liver cancer

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992128

The role of tumour-associated macrophages in tumour progression: implications for new anticancer therapies

23 August 2017

1 reference

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Hormonal therapy with megestrol in inoperable hepatocellular carcinoma characterized by variant oestrogen receptors

23 August 2017

1 reference

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Use of tamoxifen in hepatocellular carcinoma: a review and paradigm shift.

23 August 2017

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Hepatocyte nuclear factor 3beta (Foxa2) is dispensable for maintaining the differentiated state of the adult hepatocyte

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992128

Estrogen enhances immunoglobulin production by human PBMCs

23 August 2017

1 reference

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Suppressive effect of oestradiol on chemical hepatocarcinogenesis in rats

23 August 2017

1 reference

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Repression of the Interleukin-6 Promoter by Estrogen Receptor Is Mediated by NF-κB and C/EBPβ

23 August 2017

1 reference

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Prevention of spontaneous tumours in female rats by fadrozole hydrochloride, an aromatase inhibitor

23 August 2017

1 reference

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Dose-response relationships in promotion of rat hepatocarcinogenesis by 17 alpha-ethinylestradiol

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992128

Benign hepatic lesions and orally administered contraceptives. A report of seven cases and a critical analysis of the literature

23 August 2017

1 reference

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Treatment of hepatocellular carcinoma: a systematic review

23 August 2017

1 reference

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Multidisciplinary approach for HCC patients: hepatology for the oncologists

6 September 2017

1 reference

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Estrogen receptor 1 gene as a tumor suppressor gene in hepatocellular carcinoma detected by triple-combination array analysis

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992128

NF-κB and STAT3 signaling pathways collaboratively link inflammation to cancer

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992128

Oestrogen attenuates tumour progression in hepatocellular carcinoma

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992128

Clinical implications of DNA methylation in hepatocellular carcinoma

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992128

An oestrogen receptor β-selective agonist exerts anti-neoplastic effects in experimental intrahepatic cholangiocarcinoma

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992128

miR-22 promotes HBV-related hepatocellular carcinoma development in males

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992128

Expression of wild-type and variant estrogen receptor alpha in liver carcinogenesis and tumor progression

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992128

Estrogen receptor beta binds to and regulates three distinct classes of target genes

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992128

Serum IL-6 levels and the risk for hepatocarcinogenesis in chronic hepatitis C patients: an analysis based on gender differences

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992128

Androgen metabolism and biotransformation in nontumoral and malignant human liver tissues and cells

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992128

High serum interleukin-6 level predicts future hepatocellular carcinoma development in patients with chronic hepatitis B.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992128

MicroRNA-18a prevents estrogen receptor-alpha expression, promoting proliferation of hepatocellular carcinoma cells

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992128

Inhibiting Stat3 signaling in the hematopoietic system elicits multicomponent antitumor immunity

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992128

Hepatic regeneration and growth factors

14 September 2017

1 reference

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Carcinoma of the prostate: the therapeutic dilemma

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992128

Primary liver tumors and oral contraceptives. Results of a survey

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992128

The role of CBP in estrogen receptor cross-talk with nuclear factor-kappaB in HepG2 cells

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992128

Molecular mechanisms of estrogen carcinogenesis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992128

Modulation of transforming growth factor-beta production in normal human osteoblast-like cells by 17 beta-estradiol and parathyroid hormone

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992128

The inflammatory microenvironment in hepatocellular carcinoma: a pivotal role for tumor-associated macrophages

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992128

ER-alpha36, a novel variant of ER-alpha, is expressed in ER-positive and -negative human breast carcinomas

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992128

DNA methylation and environmental exposures in human hepatocellular carcinoma

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992128

Endocrine treatment of hepatocellular carcinoma. Any evidence of benefit?

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992128

Effect of estradiol on cytokine secretion by proteolipid protein-specific T cell clones isolated from multiple sclerosis patients and normal control subjects

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992128

Enhancement of hepatocarcinogenesis in female rats by ethinyl estradiol and mestranol but not estradiol

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992128

Role of estrogens as promoters of hepatic neoplasia

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992128

Progesterone and estradiol modulate interleukin-1 beta messenger ribonucleic acid levels in cultured human peripheral monocytes

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992128

Estrogen-sensitive PTPRO expression represses hepatocellular carcinoma progression by control of STAT3.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992128

Dr. Jekyll and Mr. Hyde: a paradoxical oncogenic and tumor suppressive role of signal transducer and activator of transcription 3 in liver cancer.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992128

Hypomethylation of long interspersed nuclear element-1 in hepatocellular carcinomas.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992128

Inflammation, HCC and sex: IL-6 in the centre of the triangle

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992128

Evaluation of interleukin-6, interleukin-10 and human hepatocyte growth factor as tumor markers for hepatocellular carcinoma.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992128

Deletion of the SOCS3 gene in liver parenchymal cells promotes hepatitis-induced hepatocarcinogenesis.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992128

Ubiquitous activation of Ras and Jak/Stat pathways in human HCC.

1 September 2018

1 reference

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Constitutive activation of NF-kappaB in human hepatocellular carcinoma: evidence of a cytoprotective role.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992128

HBsAg and HBx knocked into the p21 locus causes hepatocellular carcinoma in mice.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992128

Estrogen receptor beta inhibits human breast cancer cell proliferation and tumor formation by causing a G2 cell cycle arrest

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992128

Local estrogen formation by nontumoral, cirrhotic, and malignant human liver tissues and cells.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992128

The clinical and pathogenetic significance of estrogen receptor-beta expression in chronic liver diseases and liver carcinoma.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992128

The Role of Hepatocyte Nuclear Factor-3α (Forkhead Box A1) and Androgen Receptor in Transcriptional Regulation of Prostatic Genes

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992128

High-dose tamoxifen in the treatment of inoperable hepatocellular carcinoma: A multicenter randomized controlled trial

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992128

Estrogen inhibition of EAE involves effects on dendritic cell function.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992128

17Beta-estradiol inhibits the adhesion of leukocytes in TNF-alpha stimulated human endothelial cells by blocking IL-8 and MCP-1 secretion, but not its transcription

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992128

17beta-estradiol, progesterone, and dihydrotestosterone suppress the growth of human melanoma by inhibiting interleukin-8 production.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992128

The effect of 17beta-estradiol on production of cytokines in cultures of peripheral blood.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992128

Trends in survival of patients with hepatocellular carcinoma between 1977 and 1996 in the United States.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992128

Complex interactions between sex steroids and cytokines in the human pregnant myometrium: evidence for an autocrine signaling system at term.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992128

Variant liver estrogen receptor transcripts already occur at an early stage of chronic liver disease

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992128

Prevention of DMBA-induced rat mammary carcinomas comparing leuprolide, oophorectomy, and tamoxifen.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992128

Does postmenopausal estrogen administration increase the risk of breast cancer? Contributions of animal, biochemical, and clinical investigative studies to a resolution of the controversy

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992128

Estrogen Receptor Classification for Hepatocellular Carcinoma: Comparison With Clinical Staging Systems

1 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1186%2F1479-5876-12-93

Sorafenib use in hepatocellular carcinoma: more questions than answers

21 January 2018

1 reference

12 December 2020

Intratumoral aromatase in human breast, endometrial, and ovarian malignancies

1 reference

12 December 2020

Natural history of inoperable hepatocellular carcinoma: estrogen receptors' status in the tumor is the strongest prognostic factor for survival

1 reference

12 December 2020

Effects of estrogen on interleukin-6 production in rheumatoid fibroblast-like synoviocytes

1 reference

12 December 2020

Localized aberrant expression of cytochrome P450 aromatase in primary and metastatic malignant tumors of human liver

1 reference

12 December 2020

Role of reproductive factors in hepatocellular carcinoma: Impact on hepatitis B- and C-related risk

1 reference

12 December 2020

Type of estrogen receptor determines response to antiestrogen therapy

1 reference

12 December 2020

Promotive effects of ethinyl estradiol in hepatocarcinogenesis initiated by diethylnitrosamine in male rats

1 reference

12 December 2020

Hepatocellular carcinoma in alcoholic cirrhosis: is sex hormone imbalance a pathogenetic factor?

1 reference

12 December 2020

Variant estrogen receptor messenger RNA species detected in human primary hepatocellular carcinoma

1 reference

12 December 2020

Experimental models for the study of prostatic adenocarcinoma

1 reference

12 December 2020

Oral contraceptive steroids as promoters of hepatocarcinogenesis in female Sprague-Dawley rats

1 reference

12 December 2020

Identifiers

DOI

10.1186/1479-5876-12-93

1 reference

Dimensions Publication ID

22 August 2017

0 references

1 reference

22 August 2017

PubMed publication ID

24708807

1 reference