Drug delivery systems and liver targeting for the improved pharmacotherapy of the hepatitis B virus (HBV) infection (Q37718052)

22 August 2017

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Drug delivery systems and liver targeting for the improved pharmacotherapy of the hepatitis B virus (HBV) infection (English)

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22 August 2017

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María L Cuestas

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22 August 2017

Verónica L Mathet

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2

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22 August 2017

José R Oubiña

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22 August 2017

Alejandro Sosnik

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4

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22 August 2017

24 March 2010

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22 August 2017

Pharmaceutical Research

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22 August 2017

27

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22 August 2017

1184-1202

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22 August 2017

7

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Recent advances in hepatitis B virus research: a German point of view

22 August 2017

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https://api.crossref.org/works/10.1007%2FS11095-010-0112-Z

Antiviral therapy and resistance with hepatitis B virus infection

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11095-010-0112-Z

Transmission of hepatitis B virus to gibbons by exposure to human saliva containing hepatitis B surface antigen

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11095-010-0112-Z

Experimental transmission of hepatitis B virus by semen and saliva

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11095-010-0112-Z

Hepatitis B virus resistance to nucleos(t)ide analogues.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11095-010-0112-Z

The accumulation mechanism of cationic mitomycin C-dextran conjugates in the liver: in-vivo cellular localization and in-vitro interaction with hepatocytes

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11095-010-0112-Z

Stealth and cunning: hepatitis B and hepatitis C viruses

21 January 2018

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12 December 2020

Telbivudine for the management of chronic hepatitis B virus infection

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12 December 2020

Clinical significance of hepatitis B virus genotypes, variants, and mutants

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12 December 2020

Hepatitis B virus polymerase variants associated with entecavir drug resistance in treatment-naive patients.

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12 December 2020

Drug targets and molecular mechanisms of drug resistance in chronic hepatitis B.

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12 December 2020

New old challenges in tuberculosis: potentially effective nanotechnologies in drug delivery.

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12 December 2020

Entecavir resistance is rare in nucleoside naïve patients with hepatitis B

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12 December 2020

Nanotechnology solutions for infectious diseases in developing nations. Preface

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12 December 2020

Hepatitis B virus surface antigen and polymerase gene variants: potential virological and clinical significance

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12 December 2020

Recombinant high-density lipoprotein complex as a targeting system of nosiheptide to liver cells

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12 December 2020

The case for combination antiviral therapy for chronic hepatitis B virus infection

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12 December 2020

Efficient in vivo delivery of siRNA to the liver by conjugation of alpha-tocopherol

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12 December 2020

Hepatitis B virus replication within the human spleen.

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12 December 2020

Hepatotropic conjugate of adenine arabinoside monophosphate with lactosaminated poly-L-lysine. Synthesis of the carrier and pharmacological properties of the conjugate

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12 December 2020

Long-term lamivudine therapy reduces the risk of long-term complications of chronic hepatitis B infection even in patients without advanced disease.

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12 December 2020

Galactosylated poly(L-lysine) as a hepatotropic carrier of 9-beta-D-arabinofuranosyladenine 5'-monophosphate

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12 December 2020

The polymerase L528M mutation cooperates with nucleotide binding-site mutations, increasing hepatitis B virus replication and drug resistance

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12 December 2020

Specific targeting of the antiviral drug 5-iodo 2'-deoxyuridine to the parenchymal liver cell using lactosylated poly-L-lysine

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12 December 2020

Recent advances in delivery systems for anti-HIV1 therapy

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12 December 2020

Hepatitis B virus immunopathogenesis

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12 December 2020

[Preparation of nosiheptide liposomes and its inhibitory effect on hepatitics B virus in vitro].

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12 December 2020

Molecular, immunological and clinical properties of mutated hepatitis B viruses.

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12 December 2020

Recombinant lipoproteins: lipoprotein-like lipid particles for drug targeting.

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12 December 2020

Detection of hepatitis B virus DNA in pancreas, kidney and skin of two human carriers of the virus

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12 December 2020

Genotype B and younger patient age associated with better response to low-dose therapy: a trial with pegylated/nonpegylated interferon-alpha-2b for hepatitis B e antigen-positive patients with chronic hepatitis B in China

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12 December 2020

A review of telbivudine for the management of chronic hepatitis B virus infection

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12 December 2020

New drugs for chronic hepatitis B: a review

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12 December 2020

Analysis of intrahepatic HBV-specific cytotoxic T-cells during and after acute HBV infection in humans.

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12 December 2020

Potent efficacy of entecavir (BMS-200475) in a duck model of hepatitis B virus replication

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12 December 2020

Hydrophobization and bioconjugation for enhanced siRNA delivery and targeting

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12 December 2020

Characterization of bio-nanocapsule as a transfer vector targeting human hepatocyte carcinoma by disulfide linkage modification

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12 December 2020

Therapy of chronic hepatitis B virus infection: inhibition of the viral polymerase and other antiviral strategies

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12 December 2020

Resistance to adefovir dipivoxil therapy associated with the selection of a novel mutation in the HBV polymerase

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12 December 2020

Mutations of the core promoter and response to interferon treatment in chronic replicative hepatitis B

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12 December 2020

The hepatitis B virus polymerase mutation rtV173L is selected during lamivudine therapy and enhances viral replication in vitro.

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12 December 2020

RNAi for treating hepatitis B viral infection

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12 December 2020

Nitazoxanide, tizoxanide and other thiazolides are potent inhibitors of hepatitis B virus and hepatitis C virus replication

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12 December 2020

Immunoassay detection of hepatitis B surface antigen mutants

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12 December 2020

Treatment of chronic viral hepatitis with nitazoxanide and second generation thiazolides

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12 December 2020

Identification of scavenger receptor SR-BI as a high density lipoprotein receptor

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12 December 2020

Phenylpropenamide derivatives AT-61 and AT-130 inhibit replication of wild-type and lamivudine-resistant strains of hepatitis B virus in vitro

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12 December 2020

Inhibition of hepatitis B virus replication by small interference RNA induces expression of MICA in HepG2.2.15 cells.

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12 December 2020

Antisense RNA gene therapy for studying and modulating biological processes

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12 December 2020

Drug delivery systems in HIV pharmacotherapy: what has been done and the challenges standing ahead.

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12 December 2020

Suppression of hepatitis B virus-derived human hepatocellular carcinoma by NF-kappaB-inducing kinase-specific siRNA using liver-targeting liposomes

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12 December 2020

Virus-like particles in serum of patients with Australia-antigen-associated hepatitis

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12 December 2020

Nanoparticles for human liver-specific drug and gene delivery systems: in vitro and in vivo advances

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12 December 2020

Toward controlling gene expression at will: selection and design of zinc finger domains recognizing each of the 5'-GNN-3' DNA target sequences

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12 December 2020

Lamivudine for patients with chronic hepatitis B and advanced liver disease

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12 December 2020

Selective penetration and pharmacological activity of lactosaminated albumin conjugates of adenine arabinoside 5-monophosphate (ara-AMP) in mouse liver

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12 December 2020

HBeAg-positive chronic hepatitis B: why do I treat my patients with pegylated interferon

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12 December 2020

Mechanisms of co-modified liver-targeting liposomes as gene delivery carriers based on cellular uptake and antigens inhibition effect

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12 December 2020

Enhanced inhibition of hepatitis B virus production by asialoglycoprotein receptor-directed interferon

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12 December 2020

Expression, purification, and characterization of an active RNase H domain of the hepatitis B viral polymerase

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12 December 2020

A randomized, double-blind trial comparing pegylated interferon alfa-2b to interferon alfa-2b as initial treatment for chronic hepatitis C.

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12 December 2020

Potent and persistent in vivo anti-HBV activity of chemically modified siRNAs

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12 December 2020

Resolution of liver cirrhosis using vitamin A-coupled liposomes to deliver siRNA against a collagen-specific chaperone.

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12 December 2020

Controlling HBV replication in vivo by intravenous administration of triggered PEGylated siRNA-nanoparticles

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12 December 2020

Natural products as promising drug candidates for the treatment of hepatitis B and C.

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12 December 2020

Systemic and specific delivery of small interfering RNAs to the liver mediated by apolipoprotein A-I.

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12 December 2020

Antiviral L-nucleosides specific for hepatitis B virus infection

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12 December 2020

Molecular virology of hepatitis B virus for clinicians

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12 December 2020

The immunology of hepatitis B.

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12 December 2020

Reviews for APASL guidelines: immunomodulator therapy of chronic hepatitis B.

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12 December 2020

The virological and clinical significance of mutations in the overlapping envelope and polymerase genes of hepatitis B virus

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12 December 2020

Unusual naturally occurring humoral and cellular mutated epitopes of hepatitis B virus in a chronically infected argentine patient with anti-HBs antibodies

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12 December 2020

Design, synthesis, and characterization of a series of cytochrome P(450) 3A-activated prodrugs (HepDirect prodrugs) useful for targeting phosph(on)ate-based drugs to the liver

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12 December 2020

Zinc finger proteins designed to specifically target duck hepatitis B virus covalently closed circular DNA inhibit viral transcription in tissue culture

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12 December 2020

Inhibition of human hepatitis B virus replication by AT-61, a phenylpropenamide derivative, alone and in combination with (-)beta-L-2',3'-dideoxy-3'-thiacytidine

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12 December 2020

The galactose-specific recognition system of mammalian liver: the route of ligand internalization in rat hepatocytes

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12 December 2020

Characteristics and biodistribution of soybean sterylglucoside and polyethylene glycol-modified cationic liposomes and their complexes with antisense oligodeoxynucleotide

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12 December 2020

Cooperation of HDL Receptor and Hepatic Lipase in the Selective Uptake of HDL(2)-CE by Rat Hepatic Sinusoidal Cells.

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12 December 2020

Liver-targeted drug delivery using HepDirect prodrugs

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12 December 2020

Combination of small interfering RNAs mediates greater suppression on hepatitis B virus cccDNA in HepG2.2.15 cells

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12 December 2020

Efficacy of triple therapy with thymalfasin, peginterferon alpha-2a, and ribavirin for the treatment of hispanic chronic HCV nonresponders

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12 December 2020

Drug targeting in antiviral chemotherapy. A chemically stable conjugate of 9-beta-D-arabinofuranosyl-adenine 5'-monophosphate with lactosaminated albumin accomplishes a selective delivery of the drug to liver cells

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12 December 2020

The current status of antiviral therapy of chronic hepatitis B.

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12 December 2020

Liver targeting and anti-HBV activity of reconstituted HDL-acyclovir palmitate complex.

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12 December 2020

A practical guide to the use of interferons in the management of hepatitis virus infections

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12 December 2020

Selection of a hepatitis B virus strain resistant to adefovir in a liver transplantation patient.

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12 December 2020

Novel hepatotrophic prodrugs of the antiviral nucleoside 9-(2-phosphonylmethoxyethyl)adenine with improved pharmacokinetics and antiviral activity

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12 December 2020

Galactose-specific receptors on liver cells. I. Hepatocyte and liver macrophage receptors differ in their membrane anchorage

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12 December 2020

HBV pathogenesis in animal models: recent advances on the role of platelets

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12 December 2020

Synthesis and pharmacokinetics of a new liver-specific carrier, glycosylated carboxymethyl-dextran, and its application to drug targeting

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12 December 2020

Liver targeting of antiviral nucleoside analogues through the asialoglycoprotein receptor.

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12 December 2020

Prolonged gene silencing in hepatoma cells and primary hepatocytes after small interfering RNA delivery with biodegradable poly(beta-amino esters).

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12 December 2020

Antiviral-resistant hepatitis B virus: can we prevent this monster from growing?

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12 December 2020

Nitazoxanide: a review of its use in the treatment of gastrointestinal infections

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12 December 2020

Antivirals interacting with hepatitis B virus core protein and core mutations may misdirect capsid assembly in a similar fashion

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12 December 2020

Hepatitis B genotypes and the response to interferon therapy

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12 December 2020

Ectopic beta-chain of ATP synthase is an apolipoprotein A-I receptor in hepatic HDL endocytosis

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12 December 2020

Differential receptor targeting of liver cells using 99mTc-neoglycosylated human serum albumins.

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12 December 2020

Comparison of the efficacy of thymosin alpha-1 and interferon alpha in the treatment of chronic hepatitis B: a meta-analysis

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12 December 2020

Designing transcription factor architectures for drug discovery.

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12 December 2020

Vaccine-induced escape mutant of hepatitis B virus

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12 December 2020

Hepatitis B virus infection: epidemiology and vaccination

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12 December 2020

Combinations of adefovir with nucleoside analogs produce additive antiviral effects against hepatitis B virus in vitro

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12 December 2020

The hepatitis B virus

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12 December 2020

Liver targeting of hepatitis-B antiviral lamivudine using the HepDirect prodrug technology

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12 December 2020

Optimal design and validation of antiviral siRNA for targeting hepatitis B virus

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12 December 2020

Tenofovir disoproxil fumarate versus adefovir dipivoxil for chronic hepatitis B.

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12 December 2020

The role of cytotoxic T cells and cytokines in the control of hepatitis B virus infection

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12 December 2020

Hepadnavirus assembly and reverse transcription require a multi-component chaperone complex which is incorporated into nucleocapsids

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12 December 2020

Relationship of genotypes of hepatitis B virus to mutations, disease progression and response to antiviral therapy

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12 December 2020

Bicyclol: a novel drug for treating chronic viral hepatitis B and C.

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12 December 2020

Genotyping and genomic sequencing in clinical practice

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12 December 2020

Synthesis, analysis, in vitro characterization, and in vivo disposition of a lamivudine-dextran conjugate for selective antiviral delivery to the liver.

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12 December 2020

10.1007/S11095-010-0112-Z

Identifiers

DOI

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22 August 2017

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