Therapeutic potential of IL-27 in systemic lupus erythematosus. (Q37720703)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20350048%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

review article

1 reference

title

Therapeutic potential of IL-27 in systemic lupus erythematosus (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20350048%20AND%20SRC:MED&resulttype=core&format=json

systemic lupus erythematosus

29 January 2020

main subject

1 reference

1

1 reference

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29 January 2020

Hai-Feng Pan

series ordinal

2

1 reference

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29 January 2020

author name string

Jin-Hui Tao

series ordinal

3

1 reference

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29 January 2020

Dong-Qing Ye

series ordinal

4

1 reference

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29 January 2020

language of work or name

English

0 references

publication date

1 May 2010

1 reference

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Expert Opinion on Therapeutic Targets

29 January 2020

published in

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29 January 2020

volume

14

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29 January 2020

issue

5

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29 January 2020

page(s)

479-484

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Systemic lupus erythematosus.

29 January 2020

cites work

1 reference

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Hyperproduction of IL-23 and IL-17 in patients with systemic lupus erythematosus: implications for Th17-mediated inflammation in auto-immunity.

21 January 2018

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Increased serum interleukin 17 in patients with systemic lupus erythematosus.

21 January 2018

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Expanded double negative T cells in patients with systemic lupus erythematosus produce IL-17 and infiltrate the kidneys

21 January 2018

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Laser microdissection-based analysis of cytokine balance in the kidneys of patients with lupus nephritis

21 January 2018

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Nasal anti-CD3 antibody ameliorates lupus by inducing an IL-10-secreting CD4+ CD25- LAP+ regulatory T cell and is associated with down-regulation of IL-17+ CD4+ ICOS+ CXCR5+ follicular helper T cells

21 January 2018

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Regulation of immune responses by interleukin-27.

21 January 2018

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IL-27 is a key regulator of IL-10 and IL-17 production by human CD4+ T cells

21 January 2018

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IL-27 blocks RORc expression to inhibit lineage commitment of Th17 cells

21 January 2018

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Two-sided roles of IL-27: induction of Th1 differentiation on naive CD4+ T cells versus suppression of proinflammatory cytokine production including IL-23-induced IL-17 on activated CD4+ T cells partially through STAT3-dependent mechanism.

21 January 2018

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IL-27, a heterodimeric cytokine composed of EBI3 and p28 protein, induces proliferation of naive CD4+ T cells

21 January 2018

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Commensal Gram-negative bacteria prime human dendritic cells for enhanced IL-23 and IL-27 expression and enhanced Th1 development

21 January 2018

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IL-27 subunits and its receptor (WSX-1) mRNAs are markedly up-regulated in inflammatory cells in the CNS during experimental autoimmune encephalomyelitis.

21 January 2018

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Production of IL-27 and other IL-12 family cytokines by microglia and their subpopulations.

21 January 2018

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Advances in understanding the anti-inflammatory properties of IL-27.

21 January 2018

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Regulation of IL-27 p28 gene expression in macrophages through MyD88- and interferon-gamma-mediated pathways

21 January 2018

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EBV-induced gene 3 transcription is induced by TLR signaling in primary dendritic cells via NF-kappa B activation.

21 January 2018

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Novel IL-12 family members shed light on the orchestration of Th1 responses

21 January 2018

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WSX-1 and glycoprotein 130 constitute a signal-transducing receptor for IL-27

21 January 2018

1 reference

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IL-27 and IFN-αSignal via Stat1 and Stat3 and Induce T-Bet and IL-12Rβ2 in Naive T Cells

21 January 2018

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Cutting Edge: Role of IL-27/WSX-1 Signaling for Induction of T-Bet Through Activation of STAT1 During Initial Th1 Commitment

21 January 2018

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Regulation of the foxp3 gene by the Th1 cytokines: the role of IL-27-induced STAT1.

21 January 2018

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WSX-1 is required for resistance to Trypanosoma cruzi infection by regulation of proinflammatory cytokine production

21 January 2018

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Interleukin 27 signaling pathways in regulation of immune and autoimmune responses

21 January 2018

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IL-23 drives a pathogenic T cell population that induces autoimmune inflammation

21 January 2018

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Th17 cells in rheumatoid arthritis and systemic lupus erythematosus

21 January 2018

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Interleukin 27 limits autoimmune encephalomyelitis by suppressing the development of interleukin 17-producing T cells

21 January 2018

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Augmentation of antigen-presenting and Th1-promoting functions of dendritic cells by WSX-1(IL-27R) deficiency.

21 January 2018

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Interleukin 27: a double-edged sword for offense and defense

21 January 2018

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Development of Th1-type immune responses requires the type I cytokine receptor TCCR

21 January 2018

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IL-27 regulates IL-12 responsiveness of naive CD4+ T cells through Stat1-dependent and -independent mechanisms

21 January 2018

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Persistent mitochondrial hyperpolarization, increased reactive oxygen intermediate production, and cytoplasmic alkalinization characterize altered IL-10 signaling in patients with systemic lupus erythematosus

21 January 2018

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Aberrant transcription caused by the insertion of an early transposable element in an intron of the Fas antigen gene of lpr mice

21 January 2018

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Deficiency in EBV-induced gene 3 (EBI3) in MRL/lpr mice results in pathological alteration of autoimmune glomerulonephritis and sialadenitis.

21 January 2018

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Amelioration of human lupus-like phenotypes in MRL/lpr mice by overexpression of interleukin 27 receptor alpha (WSX-1).

21 January 2018

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Microarray analysis of glomerular gene expression in murine lupus nephritis

21 January 2018

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Cytokine IL-6 and IL-10 as Biomarkers in Systemic Lupus Erythematosus

21 January 2018

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10.1517/14728221003769911

21 January 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20350048%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

1 reference