Efflux pump inhibitors: a strategy to combat P-glycoprotein and the NorA multidrug resistance pump (Q37725822)

22 August 2017

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title

Efflux pump inhibitors: a strategy to combat P-glycoprotein and the NorA multidrug resistance pump (English)

1 reference

22 August 2017

multiple drug resistance

1 reference

Ling Zhang

1

1 reference

PubMed ID

20373322

22 August 2017

Shutao Ma

series ordinal

2

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22 August 2017

1 June 2010

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22 August 2017

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22 August 2017

5

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22 August 2017

6

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22 August 2017

811-822

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Cell biological mechanisms of multidrug resistance in tumors

22 August 2017

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000006

Biochemistry of multidrug resistance mediated by the multidrug transporter

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000006

Bacteria lacking a multidrug pump: a sensitive tool for drug discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000006

Clinically relevant chromosomally encoded multidrug resistance efflux pumps in bacteria

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000006

Identification and characterization of inhibitors of multidrug resistance efflux pumps in Pseudomonas aeruginosa: novel agents for combination therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000006

New-generation efflux pump inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000006

Potential role of non-antibiotics (helper compounds) in the treatment of multidrug-resistant Gram-negative infections: mechanisms for their direct and indirect activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000006

Inhibitors of efflux pumps in Gram-negative bacteria

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000006

Mechanisms and strategies to overcome multiple drug resistance in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000006

The MRP family of drug efflux pumps

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000006

Efflux-mediated antimicrobial resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000006

The role of multidrug resistance efflux transporters in antifolate resistance and folate homeostasis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000006

Multidrug resistance reversal agent from Jatropha elliptica

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000006

Antibiotic efflux pumps in Gram-negative bacteria: the inhibitor response strategy

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000006

P-glycoprotein multidrug resistance and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000006

Biochemical, cellular, and pharmacological aspects of the multidrug transporter

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000006

Modulation of P-glycoprotein expression and function by curcumin in multidrug-resistant human KB cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000006

A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000006

The biochemistry of P-glycoprotein-mediated multidrug resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000006

Catechin gallates inhibit multidrug resistance (MDR) in Staphylococcus aureus

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000006

2,4,5-Trisubstituted imidazoles: novel nontoxic modulators of P-glycoprotein mediated multidrug resistance. Part 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000006

2,4,5-Trisubstituted imidazoles: novel nontoxic modulators of P-glycoprotein mediated multidrug resistance. Part 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000006

Oral bioavailability of docetaxel in combination with OC144-093 (ONT-093).

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000006

A phase I pharmacokinetic study of the P-glycoprotein inhibitor, ONT-093, in combination with paclitaxel in patients with advanced cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000006

Inhibitory effect of the reversal agents V-104, GF120918 and Pluronic L61 on MDR1 Pgp-, MRP1- and MRP2-mediated transport

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000006

The acridonecarboxamide GF120918 potently reverses P-glycoprotein-mediated resistance in human sarcoma MES-Dx5 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000006

Co-administration of GF120918 significantly increases the systemic exposure to oral paclitaxel in cancer patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000006

Increased oral bioavailability of topotecan in combination with the breast cancer resistance protein and P-glycoprotein inhibitor GF120918.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000006

A phase I and pharmacologic study of the MDR converter GF120918 in combination with doxorubicin in patients with advanced solid tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000006

Impact of novel MDR modulators on human cancer cells: reversal activities and induction studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000006

Ellipticine analogues and related compounds as inhibitors of reverse transcriptase and as inhibitors of the efflux pump

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000006

Multidrug reverting activity toward leukemia cells in a group of new verapamil analogues with low cardiovascular activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000006

Exploratory chemistry toward the identification of a new class of multidrug resistance reverters inspired by pervilleine and verapamil models.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000006

Structure-activity relationships of a series of tariquidar analogs as multidrug resistance modulators

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000006

Small P-gp modulating molecules: SAR studies on tetrahydroisoquinoline derivatives

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000006

Bicalutamide failure in prostate cancer treatment: involvement of Multi Drug Resistance proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000006

Design and synthesis of tetrahydroisoquinoline derivatives as potential multidrug resistance reversal agents in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000006

3-Benzyl-1,3-oxazolidin-2-ones as mGluR2 positive allosteric modulators: Hit-to lead and lead optimization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000006

Inhibition of P-glycoprotein by D-alpha-tocopheryl polyethylene glycol 1000 succinate (TPGS).

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000006

Influence of vitamin E TPGS poly(ethylene glycol) chain length on apical efflux transporters in Caco-2 cell monolayers

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000006

Inhibiting efflux with novel non-ionic surfactants: Rational design based on vitamin E TPGS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000006

Reversal of p-glycoprotein-mediated multidrug resistance by macrocyclic bisbibenzyl derivatives in adriamycin-resistant human myelogenous leukemia (K562/A02) cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000006

Efflux in bacteria: what do we really know about it?

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000006

Vancomycin-resistant Staphylococcus aureus: a new model of antibiotic resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000006

Quinupristin-dalfopristin resistance in gram-positive bacteria: mechanism of resistance and epidemiology

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000006

Fluoroquinolone resistance protein NorA of Staphylococcus aureus is a multidrug efflux transporter

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000006

Two flavonols from Artemisa annua which potentiate the activity of berberine and norfloxacin against a resistant strain of Staphylococcus aureus

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000006

Flavonolignan and flavone inhibitors of a Staphylococcus aureus multidrug resistance pump: structure-activity relationships

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000006

Structure-activity relationships of 2-aryl-1H-indole inhibitors of the NorA efflux pump in Staphylococcus aureus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000006

Synthesis of functionalized 2-aryl-5-nitro-1H-indoles and their activity as bacterial NorA efflux pump inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000006

DFT and GA studies on the QSAR of 2-aryl-5-nitro-1H-indole derivatives as NorA efflux pump inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000006

Piperine analogs as potent Staphylococcus aureus NorA efflux pump inhibitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000006

Novel structural analogues of piperine as inhibitors of the NorA efflux pump of Staphylococcus aureus

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000006

Synthesis and evaluation of PSSRI-based inhibitors of Staphylococcus aureus multidrug efflux pumps

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000006

Synthesis and evaluation of fluoroquinolone derivatives as substrate-based inhibitors of bacterial efflux pumps

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000006

Phenylpiperidine selective serotonin reuptake inhibitors interfere with multidrug efflux pump activity in Staphylococcus aureus

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000006

Synthesis and evaluation of new arylbenzo[b]thiophene and diarylthiophene derivatives as inhibitors of the NorA multidrug transporter of Staphylococcus aureus

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000006

Bacterial resistance modifying tetrasaccharide agents from Ipomoea murucoides

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000006

Synthesis of omeprazole analogues and evaluation of these as potential inhibitors of the multidrug efflux pump NorA of Staphylococcus aureus

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000006

Identification and biological evaluation of grapefruit oil components as potential novel efflux pump modulators in methicillin-resistant Staphylococcus aureus bacterial strains

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000006

Citral derived amides as potent bacterial NorA efflux pump inhibitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000006

The functions and structure of ABC transporters: implications for the design of new inhibitors of Pgp and MRP1 to control multidrug resistance (MDR).

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000006

Overcoming multidrug resistance in cancer: clinical studies of p-glycoprotein inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000006

7 January 2021

Diverse effects of P-glycoprotein inhibitory agents on human leukemia cells expressing the multidrug resistance protein (MRP)

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000006

7 January 2021

Design, synthesis, and in vitro activity of catamphiphilic reverters of multidrug resistance: discovery of a selective, highly efficacious chemosensitizer with potency in the nanomolar range

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000006

7 January 2021

Reversal of P-glycoprotein mediated multidrug resistance by novel anthranilamide derivatives

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000006

7 January 2021

Direct synthesis of chrysosplenol D

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000006

7 January 2021

Conjugating berberine to a multidrug efflux pump inhibitor creates an effective antimicrobial

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000006

7 January 2021

N-caffeoylphenalkylamide derivatives as bacterial efflux pump inhibitors

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000006

7 January 2021

Polyacylated oligosaccharides from medicinal Mexican morning glory species as antibacterials and inhibitors of multidrug resistance in Staphylococcus aureus

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000006

7 January 2021

Identifiers

DOI

10.1002/CMDC.201000006

1 reference

22 August 2017

1 reference

PubMed ID

20373322