Potential role of IFNα in adult lupus (Q37730992)

22 August 2017

5 references

12 March 2019

13 March 2019

17 June 2019

30 June 2019

20 November 2019

Potential role of IFNα in adult lupus (English)

1 reference

systemic lupus erythematosus

22 August 2017

5 references

12 March 2019

13 March 2019

17 June 2019

30 June 2019

20 November 2019

1 reference

20 November 2019

Lars Rönnblom

1

1 reference

22 August 2017

14 April 2010

6 references

Arthritis Research and Therapy

22 August 2017

12 March 2019

13 March 2019

17 June 2019

30 June 2019

20 November 2019

6 references

22 August 2017

12 March 2019

13 March 2019

17 June 2019

30 June 2019

20 November 2019

12 Suppl 1

1 reference

22 August 2017

S3

1 reference

https://scigraph.springernature.com/pub.10.1186/ar2884

22 August 2017

0 references

cites work

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A STAT4 risk allele is associated with ischaemic cerebrovascular events and anti-phospholipid antibodies in systemic lupus erythematosus

23 August 2017

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Neutralization of interferon-alpha/beta-inducible genes and downstream effect in a phase I trial of an anti-interferon-alpha monoclonal antibody in systemic lupus erythematosus

23 August 2017

1 reference

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Recent insights into the genetic basis of systemic lupus erythematosus

23 August 2017

1 reference

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Identification of IRAK1 as a risk gene with critical role in the pathogenesis of systemic lupus erythematosus

23 August 2017

1 reference

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Multiple polymorphisms in the TNFAIP3 region are independently associated with systemic lupus erythematosus

23 August 2017

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Genetic variants near TNFAIP3 on 6q23 are associated with systemic lupus erythematosus

23 August 2017

1 reference

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Potent induction of IFN-alpha and chemokines by autoantibodies in the cerebrospinal fluid of patients with neuropsychiatric lupus

23 August 2017

1 reference

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Interactions among type I and type II interferon, tumor necrosis factor, and beta-estradiol in the regulation of immune response-related gene expressions in systemic lupus erythematosus

23 August 2017

1 reference

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Cutting edge: autoimmune disease risk variant of STAT4 confers increased sensitivity to IFN-alpha in lupus patients in vivo.

23 August 2017

1 reference

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Autoreactive B cells discriminate CpG-rich and CpG-poor DNA and this response is modulated by IFN-alpha

23 August 2017

1 reference

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Association of elevated transcript levels of interferon-inducible chemokines with disease activity and organ damage in systemic lupus erythematosus patients

23 August 2017

1 reference

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Toll-like receptor-mediated induction of type I interferon in plasmacytoid dendritic cells requires the rapamycin-sensitive PI(3)K-mTOR-p70S6K pathway

23 August 2017

1 reference

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Association of the IRF5 risk haplotype with high serum interferon-alpha activity in systemic lupus erythematosus patients

23 August 2017

1 reference

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Plasmacytoid dendritic cells: sensing nucleic acids in viral infection and autoimmune diseases.

23 August 2017

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Development of TLR inhibitors for the treatment of autoimmune diseases

23 August 2017

1 reference

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A risk haplotype of STAT4 for systemic lupus erythematosus is over-expressed, correlates with anti-dsDNA and shows additive effects with two risk alleles of IRF5.

23 August 2017

1 reference

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Specificity of the STAT4 genetic association for severe disease manifestations of systemic lupus erythematosus

23 August 2017

1 reference

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Systemic IFN-alpha drives kidney nephritis in B6.Sle123 mice

23 August 2017

1 reference

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The innate immune system in SLE: type I interferons and dendritic cells

23 August 2017

1 reference

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Apoptosis in the pathogenesis of systemic lupus erythematosus.

23 August 2017

1 reference

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Plasmacytoid dendritic cells and type I IFN: 50 years of convergent history

23 August 2017

1 reference

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STAT4 and the risk of rheumatoid arthritis and systemic lupus erythematosus

23 August 2017

1 reference

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Interferon-alpha promotes abnormal vasculogenesis in lupus: a potential pathway for premature atherosclerosis

23 August 2017

1 reference

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High serum IFN-alpha activity is a heritable risk factor for systemic lupus erythematosus

23 August 2017

1 reference

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TLR-dependent and TLR-independent pathways of type I interferon induction in systemic autoimmunity

23 August 2017

1 reference

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Toll-like receptor 9-dependent activation by DNA-containing immune complexes is mediated by HMGB1 and RAGE

23 August 2017

1 reference

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Elevated serum levels of interferon-regulated chemokines are biomarkers for active human systemic lupus erythematosus

23 August 2017

1 reference

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Association of increased interferon-inducible gene expression with disease activity and lupus nephritis in patients with systemic lupus erythematosus

23 August 2017

1 reference

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The type I interferon system in systemic lupus erythematosus

23 August 2017

1 reference

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Immune stimulation mediated by autoantigen binding sites within small nuclear RNAs involves Toll-like receptors 7 and 8.

23 August 2017

1 reference

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Cross-regulation of TNF and IFN-alpha in autoimmune diseases

23 August 2017

1 reference

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Neuropsychiatric adverse effects of interferon-alpha: recognition and management

23 August 2017

1 reference

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Polymorphisms in the tyrosine kinase 2 and interferon regulatory factor 5 genes are associated with systemic lupus erythematosus

23 August 2017

1 reference

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Early events in lupus humoral autoimmunity suggest initiation through molecular mimicry

23 August 2017

1 reference

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Interferons, interferon-like cytokines, and their receptors

23 August 2017

1 reference

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Characterization of heterogeneity in the molecular pathogenesis of lupus nephritis from transcriptional profiles of laser-captured glomeruli

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2991776

Microarray analysis of gene expression in lupus

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2991776

Plasmacytoid dendritic cells induce plasma cell differentiation through type I interferon and interleukin 6

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2991776

Type-I interferon receptor deficiency reduces lupus-like disease in NZB mice

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2991776

Interferon and granulopoiesis signatures in systemic lupus erythematosus blood

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2991776

Interferon-inducible gene expression signature in peripheral blood cells of patients with severe lupus

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2991776

The natural interferon-alpha producing cells in systemic lupus erythematosus

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2991776

BDCA-2, a novel plasmacytoid dendritic cell-specific type II C-type lectin, mediates antigen capture and is a potent inhibitor of interferon alpha/beta induction

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2991776

IFNs activate toll-like receptor gene expression in viral infections

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2991776

An etiopathogenic role for the type I IFN system in SLE.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2991776

Current evidence for the induction of autoimmune rheumatic manifestations by cytokine therapy

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2991776

Interferon-induced 2'-5' adenylate synthetase in vivo and interferon production in vitro by lymphocytes from systemic lupus erythematosus patients with and without circulating interferon

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2991776

Comparative analysis of IRF and IFN-alpha expression in human plasmacytoid and monocyte-derived dendritic cells

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2991776

Interferon-alpha induces up-regulation and nuclear translocation of the Ro52 autoantigen as detected by a panel of novel Ro52-specific monoclonal antibodies

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2991776

Pre-assembly of STAT4 with the human IFN-alpha/beta receptor-2 subunit is mediated by the STAT4 N-domain

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2991776

Functional assay of type I interferon in systemic lupus erythematosus plasma and association with anti-RNA binding protein autoantibodies

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2991776

Cutting edge: a T-bet-independent role for IFN-alpha/beta in regulating IL-2 secretion in human CD4+ central memory T cells

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2991776

Interferon-alpha in lupus psychosis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2991776

Induction of interferon-alpha by immune complexes or liposomes containing systemic lupus erythematosus autoantigen- and Sjögren's syndrome autoantigen-associated RNA.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2991776

Plasmacytoid dendritic cells (natural interferon- alpha/beta-producing cells) accumulate in cutaneous lupus erythematosus lesions

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2991776

MX homologous protein in mononuclear cells from patients with systemic lupus erythematosus.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2991776

Possible induction of systemic lupus erythematosus by interferon-α treatment in a patient with a malignant carcinoid tumour

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2991776

Immune Interferon in the Circulation of Patients with Autoimmune Disease

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2991776

Regulation of the interferon-alpha production induced by RNA-containing immune complexes in plasmacytoid dendritic cells.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2991776

Cutting edge: enhancement of antibody responses through direct stimulation of B and T cells by type I IFN.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2991776

Peripheral blood lymphocyte apoptosis and circulating dendritic cells in patients with systemic lupus erythematosus: correlation with immunological status and disease-related symptoms

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2991776

Activation of the interferon-alpha pathway identifies a subgroup of systemic lupus erythematosus patients with distinct serologic features and active disease.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2991776

Induction of interferon-alpha production in plasmacytoid dendritic cells by immune complexes containing nucleic acid released by necrotic or late apoptotic cells and lupus IgG.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2991776

Activation of type I interferon system in systemic lupus erythematosus correlates with disease activity but not with antiretroviral antibodies

1 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1186%2FAR2884

Comprehensive evaluation of the genetic variants of interferon regulatory factor 5 (IRF5) reveals a novel 5 bp length polymorphism as strong risk factor for systemic lupus erythematosus

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1186%2FAR2884

Lack of association between the interferon-alpha signature and longitudinal changes in disease activity in systemic lupus erythematosus

21 January 2018

1 reference

12 December 2020

C1q inhibits immune complex-induced interferon-alpha production in plasmacytoid dendritic cells: a novel link between C1q deficiency and systemic lupus erythematosus pathogenesis

1 reference

12 December 2020

Autoimmunity after alpha-interferon therapy for malignant carcinoid tumors

1 reference

12 December 2020

Patients with systemic lupus erythematosus have reduced numbers of circulating natural interferon-alpha- producing cells

1 reference

12 December 2020

Patients with systemic lupus erythematosus (SLE) have a circulating inducer of interferon-alpha (IFN-alpha) production acting on leucocytes resembling immature dendritic cells

1 reference

12 December 2020

Anti-double-stranded DNA antibodies and immunostimulatory plasmid DNA in combination mimic the endogenous IFN-alpha inducer in systemic lupus erythematosus

1 reference

12 December 2020

Presence of cutaneous interferon-alpha producing cells in patients with systemic lupus erythematosus

1 reference

12 December 2020

Activation of natural interferon-alpha producing cells by apoptotic U937 cells combined with lupus IgG and its regulation by cytokines

1 reference

12 December 2020

Type I Interferon controls the onset and severity of autoimmune manifestations in lpr mice

1 reference

12 December 2020

Analysis of gene expression profiles in human systemic lupus erythematosus using oligonucleotide microarray

1 reference

12 December 2020

Fc gamma RIIa is expressed on natural IFN-alpha-producing cells (plasmacytoid dendritic cells) and is required for the IFN-alpha production induced by apoptotic cells combined with lupus IgG

1 reference

12 December 2020

Expression of the markers BDCA-2 and BDCA-4 and production of interferon-alpha by plasmacytoid dendritic cells in systemic lupus erythematosus

1 reference

12 December 2020

Development of Autoantibodies before the Clinical Onset of Systemic Lupus Erythematosus

1 reference

12 December 2020

Serum interferon levels in patients with systemic lupus erythematosus

1 reference

12 December 2020

Association of polymorphisms across the tyrosine kinase gene, TYK2 in UK SLE families

1 reference

12 December 2020

Synergistic proinflammatory effects of the antiviral cytokine interferon-alpha and Toll-like receptor 4 ligands in the atherosclerotic plaque

1 reference

12 December 2020

Glomerular accumulation of plasmacytoid dendritic cells in active lupus nephritis: role of interleukin-18

1 reference

12 December 2020

Sialic acid-binding Ig-like lectin 1 expression in inflammatory and resident monocytes is a potential biomarker for monitoring disease activity and success of therapy in systemic lupus erythematosus

1 reference

12 December 2020

Identifiers

DOI

10.1186/AR2884

1 reference

PMCID

2991776

Dimensions Publication ID

22 August 2017

0 references

1 reference

22 August 2017

1 reference

PMCID

2991776