Treatment of chronic obstructive pulmonary disease with roflumilast, a new phosphodiesterase 4 inhibitor (Q37732234)

22 August 2017

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title

Treatment of chronic obstructive pulmonary disease with roflumilast, a new phosphodiesterase 4 inhibitor (English)

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chronic obstructive pulmonary disease

22 August 2017

main subject

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author name string

Nicholas J Gross

series ordinal

1

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22 August 2017

Mark A Giembycz

series ordinal

2

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22 August 2017

Stephen I Rennard

series ordinal

3

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22 August 2017

language of work or name

English

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publication date

1 April 2010

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COPD: Journal of Chronic Obstructive Pulmonary Disease

22 August 2017

published in

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22 August 2017

volume

7

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22 August 2017

issue

2

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22 August 2017

page(s)

141-153

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Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease. NHLBI/WHO Global Initiative for Chronic Obstructive Lung Disease (GOLD) Workshop summary

22 August 2017

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21 January 2018

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Cilomilast: a second generation phosphodiesterase 4 inhibitor for asthma and chronic obstructive pulmonary disease

21 January 2018

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Could isoenzyme-selective phosphodiesterase inhibitors render bronchodilator therapy redundant in the treatment of bronchial asthma?

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Phosphodiesterase 4 inhibitors and the treatment of asthma: where are we now and where do we go from here?

21 January 2018

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Phosphodiesterase 4 inhibitors in chronic obstructive pulmonary disease: a new approach to oral treatment

21 January 2018

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Roflumilast: an oral, once-daily selective PDE-4 inhibitor for the management of COPD and asthma

21 January 2018

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Lack of DNA binding in the rat nasal mucosa and other tissues of the nasal toxicants roflumilast, a phosphodiesterase 4 inhibitor, and a metabolite, 4-amino-3,5-dichloropyridine, in contrast to the nasal carcinogen 2,6-dimethylaniline

21 January 2018

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Roflumilast fully prevents emphysema in mice chronically exposed to cigarette smoke

21 January 2018

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Effect of roflumilast on inflammatory cells in the lungs of cigarette smoke-exposed mice

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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The new phosphodiesterase 4 inhibitor roflumilast is efficacious in exercise-induced asthma and leads to suppression of LPS-stimulated TNF-alpha ex vivo

21 January 2018

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Antiinflammatory effects of the phosphodiesterase-4 inhibitor cilomilast (Ariflo) in chronic obstructive pulmonary disease

21 January 2018

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Investigation of a potential food effect on the pharmacokinetics of roflumilast, an oral, once-daily phosphodiesterase 4 inhibitor, in healthy subjects.

21 January 2018

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Single-dose pharmacokinetics of roflumilast in children and adolescents

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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The targeted oral, once-daily phosphodiesterase 4 inhibitor roflumilast and the leukotriene receptor antagonist montelukast do not exhibit significant pharmacokinetic interactions

21 January 2018

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Influence of Cigarette Smoking on Drug Metabolism in Man

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Deletion of phosphodiesterase 4D in mice shortens alpha(2)-adrenoceptor-mediated anesthesia, a behavioral correlate of emesis

21 January 2018

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Ariflo (SB 207499), a second generation phosphodiesterase 4 inhibitor for the treatment of asthma and COPD: from concept to clinic

21 January 2018

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Roflumilast: a phosphodiesterase-4 inhibitor for the treatment of respiratory disease

21 January 2018

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Effect of theophylline on the rate of moderate to severe exacerbations among patients with chronic obstructive pulmonary disease

21 January 2018

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21 January 2018

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Design of phosphodiesterase 4D (PDE4D) allosteric modulators for enhancing cognition with improved safety

21 January 2018

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Potential adverse effects of bronchodilators in the treatment of airways obstruction in older people: recommendations for prescribing

21 January 2018

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Differences in Airway Inflammation in Patients with Fixed Airflow Obstruction Due to Asthma or Chronic Obstructive Pulmonary Disease

21 January 2018

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Effect of 1-Year Treatment with Roflumilast in Severe Chronic Obstructive Pulmonary Disease

21 January 2018

1 reference

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10.3109/15412551003758304

21 January 2018

Identifiers

DOI

1 reference

22 August 2017

1 reference